Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Trypanocidal Drugs"'
Autor:
Dikeledi P. Malatji
Publikováno v:
Veterinary World, Vol 15, Iss 4, Pp 1031-1043 (2022)
Trypanosomiasis is a disease caused by unicellular protozoan parasites. Small ruminants succumb to trypanosomiasis in areas of high tsetse fly challenge, resulting in serious economic loss often to farmers in low-input smallholder systems. At present
Externí odkaz:
https://doaj.org/article/b4b6f2208a9343cd9172a297b0cd0a97
Publikováno v:
Open Veterinary Science, Vol 2, Iss 1, Pp 81-90 (2021)
Trypanosomiasis is an impediment to cattle production and other agricultural development in tsetse-infested areas. It is a severe parasitic disease that causes loss in the production and performance of cattle. Hence, the aim of this paper is to revie
Externí odkaz:
https://doaj.org/article/634d3b9e1b9a41a095e39ea9b06356a2
Autor:
Cynthia Vanesa Rivero, Santiago José Martínez, Paul Novick, Juan Agustín Cueto, Betiana Nebaí Salassa, María Cristina Vanrell, Xiaomo Li, Carlos Alberto Labriola, Luis Mariano Polo, David M. Engman, Joachim Clos, Patricia Silvia Romano
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts. These qualities and the lack of an effective treatment for the chronic stage
Externí odkaz:
https://doaj.org/article/666fd847b79d4112a600e54b6516dd1b
Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing
Autor:
Chantal Reigada, Melisa Sayé, Otto Phanstiel, Edward Valera-Vera, Mariana R. Miranda, Claudio A. Pereira
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo. Therefore, the upt
Externí odkaz:
https://doaj.org/article/6bb2ba388e5243ae9d06912e36271213
Akademický článek
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Autor:
Sloan, MA, Ligoxygakis, P
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 5, Pp 1613-1616 (2020)
Trypanosomatid parasites are causative agents of important human and animal diseases such as sleeping sickness and leishmaniasis. Most trypanosomatids are transmitted to their mammalian hosts by insects, often belonging to Diptera (or true flies). Wi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 40, Iss 1, Pp 33-39 (2007)
No fully effective treatment has been developed since the discovery of Chagas' disease by Carlos Chagas in 1909. Since drug-resistant Trypanosoma cruzi strains are occurring and the current therapy is effectiveness in the acute phase but with various
Externí odkaz:
https://doaj.org/article/6f51151398a640b18c3a8b379e492973
Autor:
Gracious M. Diiro, Beatrice Muriithi, Michael Kidoido, Daniel K. Masiga, Nancy G. Gathogo, Michael N. Okal
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009663 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Tsetse-transmitted Animal African Trypanosomosis (AAT) is one of the most important constraints to livestock development in Africa. Use of trypanocides has been the most widespread approach for the management of AAT, despite the associated drug resis
Autor:
María Cristina Vanrell, Joachim Clos, Patricia Silvia Romano, Paul Novick, David M. Engman, Cynthia Vanesa Rivero, Luis Mariano Polo, Betiana Nebaí Salassa, Xiaomo Li, Carlos Labriola, Santiago J. Martinez, Juan Agustín Cueto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts. These qualities and the lack of an effective treatment for the chronic stage
Autor:
Hagos Ashenafi, Nigatu Kebede, Efrem Degneh, Tesfu Kassa, Getachew Terefe, Workineh Shibeshi, Kaleab Asres
Publikováno v:
Preventive Veterinary Medicine. 168:103-107
This study was conducted from May 08 to June 08, 2017 in Gidami District, Kellem Wollega Zone, Oromia Regional State, Ethiopia. The objective of the study was to assess the occurrence of trypanocidal drug resistance in naturally infected cattle in id