Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Truman Wong"'
Autor:
Danna Lynn Skea, Truman Wong, Robin Hedge, Barbara Dabek, David Nicholson Bell, Brian Wettlaufer
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 8:525-538
Adoptive cellular immunotherapy is considered a potential treatment for a wide range of diseases, including cancer, infectious diseases, and autoimmune disorders. We have developed a method using a conditioned medium, XLCM, that selectively expands s
Autor:
Robin Hedge, Barbara Dabek, Truman Wong, David Nicholson Bell, Nan-Hua Chang, Brian Wettlaufer, Danna Lynn Skea
Publikováno v:
Journal of Hematotherapy. 8:129-139
The use of human umbilical cord (UC) blood as a source of transplantable hematopoietic stem cells and progenitor cells may present some advantages over the use of BM. For example, it has been suggested that the degree of HLA matching may be less stri
Publikováno v:
Thrombosis and Haemostasis. 76:1047-1052
SummaryWe have previously reported that platelets from bleeding Simmental cattle do not aggregate in vitro in response to ADP, collagen and calcium ionophore A23187, though calcium mobilization and myosin light chain phosphorylation do occur. The agg
Publikováno v:
Thrombosis and Haemostasis. 74:1152-1162
SummaryAnti-platelet autoantibodies may be responsible for hematological complications in patients with systemic lupus erythematosus (SLE), but the mechanisms by which these antibodies cause abnormal hemostasis remain unknown. In the present study, u
Publikováno v:
Thrombosis and Haemostasis. 71:078-090
The effect of shear rate and fibrinogen concentration on adenosine diphosphate-induced aggregation of suspensions of washed human platelets in Poiseuille flow at 23 degrees C was studied using a previously described double infusion technique and resi
Publikováno v:
Biophysical Journal. 59(4):815-827
Platelet aggregation, which occurs within seconds of activation, is generally considered to be mediated by fibrinogen binding to glycoprotein IIb-IIIa which becomes expressed as a fibrinogen receptor (FbR) on the activated platelet surface. This rece
Autor:
Truman Wong, Mony M. Frojmovic
Publikováno v:
Thrombosis and Haemostasis. 64:582-588
SummaryExtinction (E) or light transmission measurements of platelet suspensions have been widely used to evaluate platelet structure and aggregation for platelet populations of varying mean platelet size (V). However, useful comparisons of platelet
Publikováno v:
Journal of autoimmunity. 8(1)
We have previously described an SLE-derived human hybridoma autoantibody, 9604, which binds to activated but not to resting platelets, inhibits platelet aggregation, and immunoprecipitates a surface-labelled polypeptide of 32,000 molecular weight (MW
We have previously reported that maximal platelet activation with adenosine diphosphate (100 microM ADP) causes rapid expression of all GPIIb-IIIa receptors for fibrinogen (FgR) (< 1-3 s), measured with FITC-labeled PAC1 by flow cytometry. We have ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b6de823ed9f878475585b9098ae492
https://europepmc.org/articles/PMC1225581/
https://europepmc.org/articles/PMC1225581/
Autor:
Truman Wong, Mony M. Frojmovic
Publikováno v:
Biophysical journal. 59(4)
Platelet aggregation has previously been shown to occur within 1 s of activation with 100 microM adenosine diphosphate (ADP) for both large (L) and small (S) platelet subpopulations, but L platelets were about twofold more sensitive and more rapidly