Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Trudi Hengeveld"'
Publikováno v:
Journal of Biological Chemistry. 276:8544-8549
Cell-cell communication via connexin-43 (Cx43)-based gap junctions is transiently inhibited by certain mitogens, but the underlying regulatory mechanisms are incompletely understood. Our previous studies have implicated the c-Src tyrosine kinase in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b63772fb5f281a14a4350d90b743706
https://doi.org/10.1074/jbc.m005847200
https://doi.org/10.1074/jbc.m005847200
Publikováno v:
Current Biology. 11:121-124
Loss of membrane potential (membrane depolarization) is one of the earliest and most striking responses of quiescent cells to stimulation with serum or G protein-coupled receptor (GPCR) agonists such as lysophosphatidic acid and thrombin [1–3]. Mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c19ebc855e23a360b4f13973a56b447
https://doi.org/10.1016/s0960-9822(01)00030-6
https://doi.org/10.1016/s0960-9822(01)00030-6
Publikováno v:
The EMBO Journal. 15:2388-2392
Sphingosine-1-phosphate (S1P) is a bioactive lysosphingolipid implicated in mitogenesis and cytoskeletal remodelling, but its mechanism of action is poorly understood. We report here that in N1E-115 neuronal cells, S1P mimics the G protein-coupled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be41f47045a427428bab6e41606fb64d
https://doi.org/10.1002/j.1460-2075.1996.tb00595.x
https://doi.org/10.1002/j.1460-2075.1996.tb00595.x
Autor:
Jacqueline Alblas, A. G. M. Bot, Kees Jalink, Friso R. Postma, H. R. De Jonge, Wouter H. Moolenaar, Trudi Hengeveld
Publikováno v:
The EMBO Journal. 15:63-72
Serum stimulation of quiescent fibroblasts leads to a dramatic depolarization of the plasma membrane; however, the identity of the active serum factor(s) and the underlying mechanism are unknown. We find that this serum activity is attributable to al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34c496d845b804bbf847d1510769aaa
https://doi.org/10.1002/j.1460-2075.1996.tb00334.x
https://doi.org/10.1002/j.1460-2075.1996.tb00334.x
Autor:
Marie-Françoise Simon, Hugues Chap, W J van Blitterswijk, Kees Jalink, G. A. Van Der Marel, Trudi Hengeveld, S Mulder, J. H. Van Boom, Wouter H. Moolenaar, Friso R. Postma
Publikováno v:
Biochemical Journal. 307:609-616
Lysophosphatidic acid (LPA; 1-acyl-sn-glycero-3-phosphate) is a platelet-derived lipid mediator that activates its own G-protein-coupled receptor to trigger phospholipase C-mediated Ca2+ mobilization and other effector pathways in numerous cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9511dc4522c532d256379d7add14250d
https://doi.org/10.1042/bj3070609
https://doi.org/10.1042/bj3070609
Publikováno v:
The Journal of Cell Biology
Addition of the bioactive phospholipid lysophosphatidic acid (LPA) or a thrombin receptor-activating peptide (TRP) to serum-starved N1E-115 or NG108-15 neuronal cells causes rapid growth cone collapse, neurite retraction, and transient rounding of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a2c8a037278fdb387dc66c9631d54e
http://europepmc.org/articles/PMC2120149
http://europepmc.org/articles/PMC2120149
Publikováno v:
Journal of Biological Chemistry. 268:5131-5138
Monoclonal antibodies were raised against purified bovine and human brain G-proteins. The epitopes recognized by three monoclonal antibodies (MONO, 3C2, and 3E7) were mapped by expressing defined parts of the bovine G(o) alpha-cDNA in bacteria, follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9202788ba60054ad7fd1fcd5d2b36f24
https://doi.org/10.1016/s0021-9258(18)53511-0
https://doi.org/10.1016/s0021-9258(18)53511-0
Publikováno v:
FEBS Letters. 308:75-78
The monoclonal antibody, MONO, recognizes an epitope on the G protein alpha o-subunit [van der Voorn et al., submitted] and readily immunoprecipitates heterotrimeric Go proteins from solubilized, crude bovine brain membranes, as well as from a purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1561b24ff4d922faebd80053adc4fb4
https://doi.org/10.1016/0014-5793(92)81054-p
https://doi.org/10.1016/0014-5793(92)81054-p
Autor:
Matthias M. Falk, Trudi Hengeveld, Hans Janssen, Wouter H. Moolenaar, Jero Calafat, Ben N G Giepmans, Ingrid Verlaan
Publikováno v:
Current biology : CB. 11(17)
Gap junctions are specialized cell-cell junctions that mediate intercellular communication. They are composed of connexin proteins, which form transmembrane channels for small molecules [1, 2]. The C-terminal tail of connexin-43 (Cx43), the most wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2b56612fa9c4f5b488b07094646ddf
https://pubmed.ncbi.nlm.nih.gov/11553331
https://pubmed.ncbi.nlm.nih.gov/11553331
Autor:
Friso R. Postma, Kees Jalink, Ben N G Giepmans, Wouter H. Moolenaar, Gerben C.M. Zondag, Trudi Hengeveld, Jacqueline Alblas
Publikováno v:
Journal of Cell Biology, 140(5), 1199-1209. ROCKEFELLER UNIV PRESS
The Journal of Cell Biology
The Journal of Cell Biology
Gap junctions mediate cell–cell communication in almost all tissues, but little is known about their regulation by physiological stimuli. Using a novel single-electrode technique, together with dye coupling studies, we show that in cells expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cfa9a81aba1831994f2de028a3b8c8
https://research.rug.nl/en/publications/60ca5d42-5cbb-4072-a5c7-8679c5ad18c3
https://research.rug.nl/en/publications/60ca5d42-5cbb-4072-a5c7-8679c5ad18c3
