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Imaging-defined necrosis after treatment with single-fraction stereotactic radiosurgery and immune checkpoint inhibitors and its potential association with improved outcomes in patients with brain metastases: an international multicenter study of 697 patients.

Autor: Lehrer EJ; 1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Ahluwalia MS; 2Department of Medical Oncology, Miami Cancer Institute, Miami, Florida., Gurewitz J; Departments of3Radiation Oncology and., Bernstein K; Departments of3Radiation Oncology and., Kondziolka D; 4Neurosurgery, NYU Langone Medical Center, New York, New York., Niranjan A; 5Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Wei Z; 5Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Lunsford LD; 5Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Fakhoury KR; 6Department of Radiation Oncology, University of Colorado, Aurora, Colorado., Rusthoven CG; 6Department of Radiation Oncology, University of Colorado, Aurora, Colorado., Mathieu D; Departments of7Neurosurgery and., Trudel C; 8Medicine, Université de Sherbrooke, Centre de recherche du CHUS, Sherbrooke, Québec, Canada., Malouff TD; 9Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida., Ruiz-Garcia H; 9Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida., Bonney P; Departments of10Neurosurgery and., Hwang L; 11Radiation Oncology, University of Southern California, Los Angeles, California., Yu C; Departments of10Neurosurgery and., Zada G; Departments of10Neurosurgery and., Patel S; 12Division of Radiation Oncology, Department of Oncology, University of Alberta, Edmonton, Alberta, Canada., Deibert CP; 13Department of Neurological Surgery, Emory University, Atlanta, Georgia., Picozzi P; 14Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Italy., Franzini A; 14Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Italy., Attuati L; 14Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Italy., Prasad RN; 15Department of Radiation Oncology, Ohio State University Wexner Medical Center, Columbus, Ohio., Raval RR; 15Department of Radiation Oncology, Ohio State University Wexner Medical Center, Columbus, Ohio., Palmer JD; 15Department of Radiation Oncology, Ohio State University Wexner Medical Center, Columbus, Ohio., Lee CC; 16Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; and., Yang HC; 16Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; and., Jones BM; 1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Green S; 1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Sheehan JP; 17Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Trifiletti DM; 9Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida.

Publikováno v: Journal of neurosurgery [J Neurosurg] 2022 Sep 16; Vol. 138 (5), pp. 1178-1187. Date of Electronic Publication: 2022 Sep 16 (Print Publication: 2023).