Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Trude G Simonsen"'
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40006 (2012)
PURPOSE: Interstitial fluid pressure (IFP) is highly elevated in many solid tumors. High IFP has been associated with low radiocurability and high metastatic frequency in human melanoma xenografts and with poor survival after radiation therapy in cer
Externí odkaz:
https://doaj.org/article/eec65a4510b8409e939350dfe92034a6
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Melanoma patients with metastatic growth in the meninges have poor prognosis and few treatment options. Although treatment with BRAF inhibitors or immune checkpoint inhibitors has provided promising results, most patients with adv
Externí odkaz:
https://doaj.org/article/f2712a4d4a734033b684fe552de5049e
Autor:
Anette Hauge, Catherine S. Wegner, Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen, Einar K. Rofstad
Publikováno v:
Translational Oncology, Vol 11, Iss 5, Pp 1128-1136 (2018)
Antiangiogenic treatment (AAT) used in combination with radiation therapy or chemotherapy is a promising strategy for the treatment of several cancer diseases. The vascularity and oxygenation of tumors may be changed significantly by AAT, and consequ
Externí odkaz:
https://doaj.org/article/1a785b7b66934e1eb7b2d5dc3a241198
Publikováno v:
Translational Oncology, Vol 10, Iss 2, Pp 158-167 (2017)
The effect of antiangiogenic agents targeting the vascular endothelial growth factor A (VEGF-A) pathway has been reported to vary substantially in preclinical studies. The purpose of this study was to investigate the effect of sunitinib treatment on
Externí odkaz:
https://doaj.org/article/e666aa00b7ff4c43aa10f86e0bc9fb07
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose The purpose of the study was to demonstrate the performance and possible applications of an intravital microscopy assay using a standard fluorescence microscope. Methods Melanoma and pancreatic ductal adenocarcinoma xenografts were initiated
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background Melanoma patients with metastatic growth in the meninges have poor prognosis and few treatment options. Although treatment with BRAF inhibitors or immune checkpoint inhibitors has provided promising results, most patients with advanced mel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 3, Pp 277-285 (2009)
Tumor blood supply was related to the morphology of the tumor microvasculature and the supplying arteries (SAs) of A-07-GFP and D-12-GFP melanoma xenografts growing in window chamber preparations in BALB/c nu/nu mice. Blood supply and morphologic par
Externí odkaz:
https://doaj.org/article/88b7e189d5e04f12b368ef90b95b489b
Autor:
Jon-Vidar Gaustad, Kjetil G. Brurberg, Trude G. Simonsen, Camilla S. Mollatt, Einar K. Rofstad
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 354-362 (2008)
Gadopentetate dimeglumine (Gd-DTPA)-based dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is considered to be a useful method for characterizing the vascularity of tumors. However, detailed studies of experimental tumors comparing DCE-
Externí odkaz:
https://doaj.org/article/764df4f4504e4b0cb3c718edafb33d2b
Autor:
Anette Hauge, Ruixia Huang, Catherine S. Wegner, Lise Mari K. Hansem, Einar K. Rofstad, Trude G. Simonsen, Jon-Vidar Gaustad
Publikováno v:
Translational Oncology, Vol 12, Iss 8, Pp 1079-1085 (2019)
Preclinical studies have suggested that interstitial fluid pressure (IFP) is uniformly elevated in the central region of tumors, whereas clinical studies have revealed that IFP may vary among different measurement sites in the tumor center. IFP measu
Autor:
Catherine S. Wegner, Kjersti V. Lund, Lise Mari K. Hansem, Anette Hauge, Einar K. Rofstad, Trude G. Simonsen, Jon-Vidar Gaustad
Publikováno v:
Cancers, Vol 12, Iss 1979, p 1979 (2020)
Cancers
Cancers
Tumor hypoxia is associated with resistance to treatment, aggressive growth, metastatic dissemination, and poor clinical outcome in many cancer types. The potential of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to assess the exten