Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Trude, Anderssen"'
Autor:
Susannah von Hofsten, Manuel K. Langer, Katja Korelin, Synnøve Magnussen, Dominik Ausbacher, Trude Anderssen, Tuula Salo, Morten B. Strøm, Annette Bayer, Ahmed Al-Samadi, Gerd Berge
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The incidence of head and neck squamous cell carcinoma (HNSCC) is increasing and the conventional treatments for this form of cancer can be tough. Despite the success of existing immunotherapies in some HNSCC patients, many do not respond to this typ
Externí odkaz:
https://doaj.org/article/4ae4b24904eb41559c8b9a2b94c79d64
Autor:
Hymonti Dey, Danijela Simonovic, Ingrid Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Trude Anderssen, Morten B. Strøm, Tor Haug
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13844
We have synthesised short analogues of the marine antimicrobial peptide Turgencin A from the colonial Arctic ascidian Synoicum turgens. In this study, we focused on a central, cationic 12-residue Cys-Cys loop region within the sequence. Modified (try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e0f86fb7635e0ad6aaccbb6c576b18
https://pubmed.ncbi.nlm.nih.gov/36430320
https://pubmed.ncbi.nlm.nih.gov/36430320
Autor:
Manuel K. Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug, Klara Stensvåg, Morten B. Strøm, Annette Bayer
Publikováno v:
European Journal of Medicinal Chemistry. 249:115147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09ded1530601480f4bb4691f7288543
https://doi.org/10.1016/j.ejmech.2023.115147
https://doi.org/10.1016/j.ejmech.2023.115147
Autor:
Manuel K. Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Francesco Zilioli, Tor Haug, Hans-Matti Blencke, Klara Stensvåg, Morten B. Strøm, Annette Bayer
Publikováno v:
European Journal of Medicinal Chemistry. 241:114632
An amphipathic barbiturate mimic of the marine eusynstyelamides is reported as a promising class of antimicrobial agents. We hereby report a detailed analysis of the structure-activity relationship for cationic amphipathic N,N′ -dialkylated-5,5-dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9160fcfce483db116bf350bd267febfa
https://doi.org/10.1016/j.ejmech.2022.114632
https://doi.org/10.1016/j.ejmech.2022.114632
Autor:
Dominik Ausbacher, Trude Anderssen, Glenn R. Morello, Hans-Matti Blencke, Manuel K Langer, Eric Juskewitz, Morten B. Strøm, Tor Haug, Laura Liikanen, Annette Bayer, Johan Isaksson, Marianne Hagensen Paulsen, Magnus Engqvist
Publikováno v:
Journal of medicinal chemistry. 64(15)
We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides. These N,N'-dialkylated-5,5-disubstituted barbiturates consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669c12a4ab3020d9d14a0f4200f8913f
https://pubmed.ncbi.nlm.nih.gov/34314189
https://pubmed.ncbi.nlm.nih.gov/34314189
Autor:
Dominik Ausbacher, Johanna U. Ericson Sollid, Terkel Hansen, Marianne Hagensen Paulsen, Annette Bayer, Tor Haug, Magnus Engqvist, Morten B. Strøm, Trude Anderssen, Jeanette Hammer Andersen
Source at https://doi.org/10.1016/j.ejmech.2019.111671. The rapid emergence and spread of multi-resistant bacteria have created an urgent need for new antimicrobial agents. We report here a series of amphipathic α,α-disubstituted β-amino amide der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e52239e41a7ff50a8b7b5706d8fdef1
https://hdl.handle.net/10037/16259
https://hdl.handle.net/10037/16259
Autor:
Marianne H, Paulsen, Eskil André, Karlsen, Dominik, Ausbacher, Trude, Anderssen, Annette, Bayer, Philipp, Ochtrop, Christian, Hedberg, Tor, Haug, Johanna U, Ericson Sollid, Morten B, Strøm
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 24(10)
The present study describes the synthesis and biological studies of a small series of head-to-tail cyclic tetrapeptides of the general structure c(Lys-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3b4062f6f2e8d07c2f5471af814bde2
https://pubmed.ncbi.nlm.nih.gov/30112781
https://pubmed.ncbi.nlm.nih.gov/30112781
Autor:
Dominik Ausbacher, Annfrid Sivertsen, Johan Isaksson, Martina Havelkova, Trude Anderssen, Morten B. Strøm, Veronika Tørfoss, Anne Elisabeth Skjørholm, Bjørn-Olav Brandsdal
Publikováno v:
Journal of Peptide Science. 20:279-291
We have in the present study explored the anticancer activity against human Burkitt's lymphoma cells (Ramos) of a series of small linear and cyclic tetrapeptides containing a β2,2-amino acid with either two 2-naphthyl-methylene or two para-CF3-benzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ac0b1b775827b7dd079af138b2ac3e
https://doi.org/10.1002/psc.2615
https://doi.org/10.1002/psc.2615
Autor:
Zack George Zachariassen, Terkel Hansen, Dominik Ausbacher, Martina Havelkova, Trude Anderssen, Morten B. Strøm
Publikováno v:
European Journal of Medicinal Chemistry. 58:22-29
We report the anticancer activity from screening of a series of synthetic β(2,2)-amino acid derivatives that were prepared to confirm the pharmacophore model of short cationic antimicrobial peptides with high anti-Staphylococcal activity. The most p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3ae876033c43de95039eb92d794cf0
https://doi.org/10.1016/j.ejmech.2012.09.048
https://doi.org/10.1016/j.ejmech.2012.09.048
Autor:
Johan Isaksson, Veronika Tørfoss, Bjørn-Olav Brandsdal, Cristiane de A. Cavalcanti-Jacobsen, Morten B. Strøm, Hans J. Vogel, Trude Anderssen, Gøril Eide Flaten, Leonard T. Nguyen, Dominik Ausbacher, Martina Havelkova
Publikováno v:
Journal of Peptide Science. 18:609-619
We have recently reported a series of synthetic anticancer heptapeptides (H-KKWβ(2,2) WKK-NH(2) ) containing a central achiral and lipophilic β(2,2) -amino acid that display low toxicity against non-malignant cells and high proteolytic stability. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cfb765b043a40caa1438570450e39a2
https://doi.org/10.1002/psc.2441
https://doi.org/10.1002/psc.2441