Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Truc Quynh Thai"'
Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function
Autor:
Mami Matsumoto, Katsuyoshi Matsushita, Masaya Hane, Chentao Wen, Chihiro Kurematsu, Haruko Ota, Huy Bang Nguyen, Truc Quynh Thai, Vicente Herranz-Pérez, Masato Sawada, Koichi Fujimoto, José Manuel García-Verdugo, Koutarou D Kimura, Tatsunori Seki, Chihiro Sato, Nobuhiko Ohno, Kazunobu Sawamoto
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1228-1253 (2024)
Abstract In the injured brain, new neurons produced from endogenous neural stem cells form chains and migrate to injured areas and contribute to the regeneration of lost neurons. However, this endogenous regenerative capacity of the brain has not yet
Externí odkaz:
https://doaj.org/article/38a75c2192bc4cdea63491e9304280eb
Autor:
Sei Saitoh, Takashi Takaki, Kazuki Nakajima, Bao Wo, Hiroshi Terashima, Satoshi Shimo, Huy Bang Nguyen, Truc Quynh Thai, Kanako Kumamoto, Kazuo Kunisawa, Shizuko Nagao, Akihiro Tojo, Nobuhiko Ohno, Kazuo Takahashi
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281770 (2023)
A long-term high-fat diet (HFD) causes obesity and changes in renal lipid metabolism and lysosomal dysfunction in mice, causing renal damage. Sodium-glucose co-transporter inhibitors, including phlorizin, exert nephroprotective effects in patients wi
Externí odkaz:
https://doaj.org/article/480b788ebb394b8aa85d01e5bfcc0fff
Autor:
Mitsuhiko Katoh, Bao Wu, Huy Bang Nguyen, Truc Quynh Thai, Ryo Yamasaki, Haiyan Lu, Anna M. Rietsch, Musab M. Zorlu, Youichi Shinozaki, Yurika Saitoh, Sei Saitoh, Takashi Sakoh, Kazuhiro Ikenaka, Schuichi Koizumi, Richard M. Ransohoff, Nobuhiko Ohno
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Microglia are the resident macrophages of the central nervous system and play complex roles in the milieu of diseases including the primary diseases of myelin. Although mitochondria are critical for cellular functions and survival in the ner
Externí odkaz:
https://doaj.org/article/52abb5ec19ee44a2bc3a37aaeb839825
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Recent advancements in electron microscope volume imaging, such as serial imaging using scanning electron microscopy (SEM), have facilitated the acquisition of three-dimensional ultrastructural information of biological samples. These advancements he
Externí odkaz:
https://doaj.org/article/b7f091520a694179afa34e4658f7a5f7
Autor:
Chihiro Kurematsu, Masato Sawada, Masaki Ohmuraya, Motoki Tanaka, Kazuya Kuboyama, Takashi Ogino, Mami Matsumoto, Hisashi Oishi, Hiroyuki Inada, Yuri Ishido, Yukina Sakakibara, Huy Bang Nguyen, Truc Quynh Thai, Shinichi Kohsaka, Nobuhiko Ohno, Maki K. Yamada, Masato Asai, Masahiro Sokabe, Junichi Nabekura, Kenichi Asano, Masato Tanaka, Kazunobu Sawamoto
Publikováno v:
Journal of Experimental Medicine. 219
New neurons, continuously added in the adult olfactory bulb (OB) and hippocampus, are involved in information processing in neural circuits. Here, we show that synaptic pruning of adult-born neurons by microglia depends on phosphatidylserine (PS), wh
Autor:
Truc Quynh Thai, Kazuya Nishimura, Shoko Takemura, Nobuhiko Ohno, Takeaki Shinjo, Tatsuhide Tanaka, Kouko Tatsumi, Sei Saitoh, Yasuyuki Osanai, Akio Wanaka
Publikováno v:
GliaREFERENCES. 69(10)
Single oligodendrocytes produce myelin sheaths around multiple axons in the central nervous system. Interfascicular oligodendrocytes (IOs) facilitate nerve conduction, but their detailed morphologies remain largely unknown. In the present study, we t
Publikováno v:
Medical Molecular Morphology. 52:135-146
Demyelination leads to axonal changes that involve the functions and dynamics of axonal mitochondria supporting metabolism and survival of axons. However, the changes in the physical interactions between mitochondria and endoplasmic reticulum, called
Autor:
Ken Muramatsu, Sei Saitoh, Satoshi Shimo, Nobuhiko Ohno, Truc Quynh Thai, Masako Ikutomo, Huy Bang Nguyen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Diabetes impairs enteric nervous system functions; however, ultrastructural changes underlying the pathophysiology of the myenteric plexus and the effects of sodium-glucose co-transporter (SGLT) inhibitors are poorly understood. This study aimed to i
Publikováno v:
Advances in experimental medicine and biology. 1190
Mitochondria play essential roles in neurons and abnormal functions of mitochondria have been implicated in neurological disorders including myelin diseases. Since mitochondrial functions are regulated and maintained by their dynamic behavior involvi
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