Zobrazeno 1 - 10
of 786
pro vyhledávání: '"Trpc channels"'
Autor:
Isaac S. Demaree, Sanjay Kumar, Kayla Tennessen, Quyen Q. Hoang, Fletcher A. White, Alexander G. Obukhov
Publikováno v:
Cells, Vol 13, Iss 23, p 2019 (2024)
Background: TRPC5 proteins form plasma membrane cation channels and are expressed in the nervous and cardiovascular systems. TRPC5 activation leads to cell depolarization and increases neuronal excitability, whereas a homologous TRPC1 inhibits TRPC5
Externí odkaz:
https://doaj.org/article/b68e04031a56411a86e0a959fc5ee365
Publikováno v:
Neurology International, Vol 15, Iss 4, Pp 1469-1479 (2023)
Canonical transient receptor potential channels (TRPCs) are a family of calcium-permeable cation channels. Previous studies have shown that heteromeric channels comprising TRPC1 and TRPC4 mediate epileptiform bursting in lateral septal neurons and hi
Externí odkaz:
https://doaj.org/article/a93e8a15c193476eb969cb3b3dce86e3
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Skin is the largest organ in the human body with ∼95% of its surface made up of keratinocytes. These cells maintain a healthy skin barrier through regulated differentiation driven by Ca2+-transcriptional coupling. Many important skin conditions ari
Externí odkaz:
https://doaj.org/article/1317014dd76c41ca905a8a9e417c8a4a
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control,
Externí odkaz:
https://doaj.org/article/e461626578524c618f5ebf7ea02e6bee
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
We investigated the contribution of excitatory transient receptor potential canonical (TRPC) cation channels to posttraumatic hyperexcitability in the brain 7 days following controlled cortical impact model of traumatic brain injury (TBI) to the pari
Externí odkaz:
https://doaj.org/article/82acaacb1a83472a8e7534a1596ed35b
Autor:
Xingjuan Chen, Natalie N. Taylor-Nguyen, Ashley M. Riley, B. Paul Herring, Fletcher A. White, Alexander G. Obukhov
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background The incidence of traumatic brain injuries (TBIs) is on the rise in the USA. Concussions, or mild TBIs without skull fracture, account for about 75% of all TBIs. Mild TBIs (mTBIs) lead to memory and cognitive deficits, headaches, i
Externí odkaz:
https://doaj.org/article/71f396e364e0435a8031f75854f568b8
Autor:
Hazel Erkan-Candag, Denis Krivic, Mathias A. F. Gsell, Mina Aleksanyan, Thomas Stockner, Rumiana Dimova, Oleksandra Tiapko, Klaus Groschner
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 799 (2022)
Azobenzene-based photochromic lipids are valuable probes for the analysis of ion channel–lipid interactions. Rapid photoisomerization of these molecules enables the analysis of lipid gating kinetics and provides information on lipid sensing. Therma
Externí odkaz:
https://doaj.org/article/95339a7f22194a6886b802bc99783e5c
Akademický článek
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