Výsledky vyhledávání - "Troy Randall"

Manipulating the epigenetic framework of T cells with histone deacetylase inhibitors for more robust and durable anti-tumor responses

Autor: Tyler R. McCaw, Mingyong Liu, Mei Li, Dmytro Starenki, Sara Cooper, Rebecca Arend, Andres Forero, Donald Buchsbaum, Troy Randall

Publikováno v: The Journal of Immunology. 200:57.41-57.41

Malignant cells often harbor an imbalance in histone acetyltransferase and histone deacetylase (HDAC) activity, which can be disrupted by HDAC inhibitors. We hypothesized that HDAC inhibition can boost anti-tumor T cell responses by modifying tumor c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eba303ba2e420347c2291c0a544ec24
https://doi.org/10.4049/jimmunol.200.supp.57.41

Zobrazit plný text záznamu

Sterile-activated cDC1 cells in neonatal lung induce T cell IL-4 production and lymph node maturation

Autor: Aaron Silva-Sanchez, Selene Meza-Perez, Sara L Stone, Troy Randall

Publikováno v: The Journal of Immunology. 198:153.16-153.16

Neonates are susceptible to respiratory tract infections, possibly due to immature pulmonary dendritic cells (cDCs). Here we assessed the development and function of conventional DCs in the lung and the lung-draining mediastinal lymph node (MedLN). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ca3caa8af5a2475524b479fde248f95
https://doi.org/10.4049/jimmunol.198.supp.153.16

Zobrazit plný text záznamu

Synthesis of thiophene-2-carboxamidines containing 2-amino-thiazoles and their biological evaluation as urokinase inhibitors

Autor: John C. Spurlino, Renee L. DesJarlais, Bruce L. Grasberger, Richard Soll, David Green, Nalin L. Subasinghe, Zhao Zhou, Christopher J. Molloy, Frank A. Lewandowski, Celia Sharp, James B. Hoffman, Kenneth J. Wilson, Troy Randall, Marie Zhang, Diane M. Maguire, Roger F. Bone, Carl R. Illig, M. Jonathan Rudolph

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 11:915-918

The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ba1899d356c2e7aa7bd0173d2b9f47
https://doi.org/10.1016/s0960-894x(01)00102-0

Zobrazit plný text záznamu

Increased PKC signaling in lupus La reactive B cells promotes development of the transitional T3 population and memory B cells in autoimmune BXD2 mice (BA3P.108)

Autor: Jennie Hamilton, Jun Li, Qi Wu, PingAr Yang, Bao Luo, Hao Li, John Bradley, Justin Taylor, Troy Randall, John Mountz, Hui-Chen Hsu

Publikováno v: The Journal of Immunology. 194:46.5-46.5

We recently identified that lupus prone BXD2 mice exhibited defective clearance of apoptotic debris. In vivo administration of excessive autologous apoptotic cells lead to elevation of IgG anti-La13-27 responses in BXD2 mice but not normal B6 mice, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::970c50dc42fedfb0f97b342cc99d5677
https://doi.org/10.4049/jimmunol.194.supp.46.5

Zobrazit plný text záznamu

Intestinal microbiota alters omental tumor growth (TUM9P.1004)

Autor: Selene Meza-Perez, Aaron Silva-Sanchez, Maria de la Luz Garcia-Hernandez, Uma Mudunuru, Javier Rangel-Moreno, Scott Simpler, Stacey Sinclair, Casey Weaver, Trenton Schoeb, Edith Lord, Troy Randall

Publikováno v: The Journal of Immunology. 194:210.6-210.6

The omentum is an adipose tissue that contains milky spots (MS). The MS are similar to secondary lymphoid organs and can generate B and T cell immune responses to peritoneal antigens. Additionally, omentum CD4+CD25+FoxP3+ T regulatory cells (Tregs) d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be06ce114bee2cde6e80c9a8561a85fd
https://doi.org/10.4049/jimmunol.194.supp.210.6

Zobrazit plný text záznamu

Deficiency in transient receptor potential melastatin 2 impairs alveolar macrophage activation and protects mice against endotoxin-induced lung inflammation and injury (INC5P.333)

Autor: Davide Botta, Uma Mudunuru, Kristen Southworth, Thomas Simpler, John Bradley, Troy Randall, Christopher Stevenson, Frances Lund

Publikováno v: The Journal of Immunology. 192:120.13-120.13

Cellular responses to reactive oxygen species (ROS) are induced by many receptors including the non-selective cation channel TRPM2 that promotes cation influx and membrane depolarization following ROS exposure, and potentiates inflammatory cytokine p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7316b16a7fe6d1cea488232ec1d74fdf
https://doi.org/10.4049/jimmunol.192.supp.120.13

Zobrazit plný text záznamu

Autoreactive B cell tetramer analysis reveals a type I interferon-mediated marginal zone precursor B cell defect in autoimmune BXD2 mice (BA12P.102)

Autor: Jennie Hamilton, Jun Li, Qi Wu, PingAr Yang, Bao Luo, John Bradley, Justin Taylor, Troy Randall, John Mountz, Hui-Chen Hsu

Publikováno v: The Journal of Immunology. 192:176.3-176.3

In human systemic lupus erythematosus and rheumatoid arthritis, development of self-reactive B cells has been associated with defective B-cell checkpoints prior to somatic hypermutation and class-switch recombination in germinal centers (GCs). To ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e86079ef89fbeda3075f7aa465ba343
https://doi.org/10.4049/jimmunol.192.supp.176.3

Zobrazit plný text záznamu

An exploration of archaeological representation : people and the domestic dog on the Great Plains of North America

Autor: Lovata, Troy Randall

Publikováno v: Digital version accessible at.

Thesis (Ph. D.)--University of Texas at Austin, 2000.
Vita. Includes bibliographical references (leaves 164-192). Available also in a digital version from Dissertation Abstracts.

Externí odkaz: http://wwwlib.umi.com/cr/utexas/main

Zobrazit plný text záznamu

Inducible bronchus-associated lymphoid tissue reduces Th2-driven pathology by redistributing leukocytes within the lung (P6214)

Autor: Ji Young Hwang, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Troy Randall

Publikováno v: The Journal of Immunology. 190:62.6-62.6

Inducible bronchus-associated lymphoid tissue (iBALT) is an ectopic lymphoid tissue formed in the lung after pulmonary infection or inflammation. This local lymphoid tissue is structurally similar to conventional secondary lymphoid organs, with separ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70ff83acdeb6c5b6f0113dfed038a059
https://doi.org/10.4049/jimmunol.190.supp.62.6

Zobrazit plný text záznamu

Specialized microenvironment within the lymph node controls antigen-presentation properties of dendritic cells and Th2 differentiation. (P1119)

Autor: Beatriz León Ruiz, André Ballesteros Tato, Troy Randall, Frances Lund

Publikováno v: The Journal of Immunology. 190:50.2-50.2

T cells need to encounter antigen-bearing dendritic cells (DCs) to undergo clonal expansion and effector development. These interactions, within lymphoid tissues, are orchestrated by the expression of chemokines and chemokine receptors. Indeed, CCR7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8adaa8e066f761eafcaeb614037ebb79
https://doi.org/10.4049/jimmunol.190.supp.50.2

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání