Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Troy KE"'
Autor:
Miriam S. Reuter, Dustin J. Sokolowski, J. Javier Diaz-Mejia, Johannes Keunen, Barbra de Vrijer, Cadia Chan, Liangxi Wang, Greg Ryan, David A. Chiasson, Troy Ketela, Stephen W. Scherer, Michael D. Wilson, Edgar Jaeggi, Rajiv R. Chaturvedi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic left heart syndrome (HLHS). To investigate if a decrease in left heart flow results in growth failure, we generate left ventricular inflow obstru
Externí odkaz:
https://doaj.org/article/8284083b8cd142eb97e9e9c59d7a03d6
Autor:
Maria Kondratyev, Aleksandra Pesic, Troy Ketela, Natalie Stickle, Christine Beswick, Zvi Shalev, Stefano Marastoni, Soroush Samadian, Anna Dvorkin-Gheva, Azin Sayad, Mikhail Bashkurov, Pedro Boasquevisque, Alessandro Datti, Trevor J. Pugh, Carl Virtanen, Jason Moffat, Reidar A. Grénman, Marianne Koritzinsky, Bradly G. Wouters
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract During cancer development, tumor cells acquire changes that enable them to invade surrounding tissues and seed metastasis at distant sites. These changes contribute to the aggressiveness of metastatic cancer and interfere with success of the
Externí odkaz:
https://doaj.org/article/886fde5b19b44a0c8e8d3f024a37afbb
Autor:
TaeHyung Kim, Hyewon Lee, Jose‐Mario Capo‐Chichi, Myung Hee Chang, Young Seok Yoo, Gurbaksh Basi, Troy Ketela, Adam C. Smith, Anne Tierens, Zhaolei Zhang, Mark D. Minden, Dennis Dong Hwan Kim
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 426-433 (2022)
Abstract Internal tandem duplication of the Feline McDonough Sarcoma (FMS)‐like tyrosine kinase 3 (FLT3‐ITD) is one of the most clinically relevant mutations in acute myeloid leukemia (AML), with a high FLT3‐ITD allelic ratio (AR) (≥0.5) bein
Externí odkaz:
https://doaj.org/article/94e0cbce20e349ae92143d8d42e6bf1b
Autor:
Deborah Watson-Jones, ProfPhD, John Changalucha, MSc, Hilary Whitworth, PhD, Ligia Pinto, PhD, Paul Mutani, MD, Jackton Indangasi, MSc, Troy Kemp, PhD, Ramadhan Hashim, BSc, Beatrice Kamala, Dip, Rebecca Wiggins, PhD, Twaib Songoro, BA, Nicholas Connor, MSc, Gladys Mbwanji, MSc, Miquel A Pavon, PhD, Brett Lowe, MSc, Devis Mmbando, BSc, Saidi Kapiga, ProfPhD, Philippe Mayaud, ProfMD, Silvia de SanJosé, MD, Joakim Dillner, ProfPhD, Richard J Hayes, ProfDSc, Charles J Lacey, ProfMD, Kathy Baisley, MSc
Publikováno v:
The Lancet Global Health, Vol 10, Iss 10, Pp e1473-e1484 (2022)
Summary: Background: An estimated 15% of girls aged 9–14 years worldwide have been vaccinated against human papillomavirus (HPV) with the recommended two-dose or three-dose schedules. A one-dose HPV vaccine schedule would be simpler and cheaper to
Externí odkaz:
https://doaj.org/article/b52f22f640384d13ab341ba7a8d80f06
Autor:
Samir H. Barghout, Ahmed Aman, Kazem Nouri, Zachary Blatman, Karen Arevalo, Geethu E. Thomas, Neil MacLean, Rose Hurren, Troy Ketela, Mehakpreet Saini, Moustafa Abohawya, Taira Kiyota, Rima Al-Awar, Aaron D. Schimmer
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
TAK-243 is a first-in-class inhibitor of ubiquitin-like modifier activating enzyme 1 that catalyzes ubiquitin activation, the first step in the ubiquitylation cascade. Based on its preclinical efficacy and tolerability, TAK-243 has been advanced to p
Externí odkaz:
https://doaj.org/article/d082e4930596459b8898e21f8ca1f16d
Akademický článek
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Autor:
Wallace LD, Troy KE
Publikováno v:
Journal of the American Academy of Nurse Practitioners; Sep2006, Vol. 18 Issue 9, p414-421, 8p
Autor:
Scott A. Yuzwa, Michael J. Borrett, Brendan T. Innes, Anastassia Voronova, Troy Ketela, David R. Kaplan, Gary D. Bader, Freda D. Miller
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3970-3986 (2017)
Adult neural stem cells (NSCs) derive from embryonic precursors, but little is known about how or when this occurs. We have addressed this issue using single-cell RNA sequencing at multiple developmental time points to analyze the embryonic murine co
Externí odkaz:
https://doaj.org/article/42cb4d38b3de47c5ab51b0e8c197f9ce
Autor:
Jinglin L. Xie, Longguang Qin, Zhengqiang Miao, Ben T. Grys, Jacinto De La Cruz Diaz, Kenneth Ting, Jonathan R. Krieger, Jiefei Tong, Kaeling Tan, Michelle D. Leach, Troy Ketela, Michael F. Moran, Damian J. Krysan, Charles Boone, Brenda J. Andrews, Anna Selmecki, Koon Ho Wong, Nicole Robbins, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Cas5 is a transcriptional regulator of responses to cell wall stress in the fungal pathogen Candida albicans. Here, Xie et al. show that Cas5 also modulates cell cycle dynamics and responses to antifungal drugs.
Externí odkaz:
https://doaj.org/article/ffb813afe4d54f829962b3863b93dbc3
Autor:
J. Javier Diaz-Mejia, Elaine C. Meng, Alexander R. Pico, Sonya A. MacParland, Troy Ketela, Trevor J. Pugh, Gary D. Bader, John H. Morris
Publikováno v:
F1000Research, Vol 8 (2019)
Background: Identification of cell type subpopulations from complex cell mixtures using single-cell RNA-sequencing (scRNA-seq) data includes automated steps from normalization to cell clustering. However, assigning cell type labels to cell clusters i
Externí odkaz:
https://doaj.org/article/25cf40df8e1541cc95186df61d5529c0