Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Troy J, Kieran"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract In vivo assessments of influenza A virus (IAV) pathogenicity and transmissibility in ferrets represent a crucial component of many pandemic risk assessment rubrics, but few systematic efforts to identify which data from in vivo experimentati
Externí odkaz:
https://doaj.org/article/62cb470c5f9f4bab9b0201229abbbaa8
Autor:
Troy J. Kieran, Xiangjie Sun, Hannah M. Creager, Terrence M. Tumpey, Taronna R. Maines, Jessica A. Belser
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-5 (2024)
Abstract Data from influenza A virus (IAV) infected ferrets provides invaluable information towards the study of novel and emerging viruses that pose a threat to human health. This gold standard model can recapitulate many clinical signs of infection
Externí odkaz:
https://doaj.org/article/300754138ad84eaaaf572c77d9e43fc0
Autor:
Joanna A. Pulit-Penaloza, Nicole Brock, Jessica A. Belser, Xiangjie Sun, Claudia Pappas, Troy J. Kieran, Poulami Basu Thakur, Hui Zeng, Dan Cui, Julia Frederick, Rodrigo Fasce, Terrence M. Tumpey, Taronna R. Maines
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses have caused large outbreaks within avian populations on five continents, with concurrent spillover into a variety of mammalian species. Mutations associated with mammalian adaptation ha
Externí odkaz:
https://doaj.org/article/c8630d5a996c44fd85855f67f6a3ca97
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012460 (2024)
Externí odkaz:
https://doaj.org/article/d99164c4580d4550a5db9062dc5ff190
Autor:
Jessica A. Belser, Troy J. Kieran, Zoë A. Mitchell, Xiangjie Sun, Kristin Mayfield, Terrence M. Tumpey, Jessica R. Spengler, Taronna R. Maines
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/73b082c9a78642089970fbfda09f67ef
Autor:
Andrea Gómez-Bravo, Sebastián Cirignoli, Diana Wehrendt, Alejandro Schijman, Cielo M. León, María Flores-Chaves, Javier Nieto, Troy J. Kieran, Marcelo Abril, Felipe Guhl
Publikováno v:
Insects, Vol 15, Iss 7, p 471 (2024)
Trypanosoma cruzi, the causative agent of Chagas disease (American trypanosomiasis), is a highly complex zoonosis that is present throughout South America, Central America, and Mexico. The transmission of this disease is influenced by various factors
Externí odkaz:
https://doaj.org/article/94e3d325af5c4e6795bb47ca117973fc
Autor:
Xiangjie Sun, Jessica A. Belser, Joanna A. Pulit-Penaloza, Nicole Brock, Troy J. Kieran, Hui Zeng, Claudia Pappas, Terrence M. Tumpey, Taronna R. Maines
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTAirborne transmissibility is a prerequisite for a pandemic influenza A virus (IAV), and a better understanding of how zoonotic IAV evolves to acquire a transmissible phenotype is essential for pandemic preparedness. Select contemporary influe
Externí odkaz:
https://doaj.org/article/73e41272b5d84883b63cd66611fc56a6
Autor:
Troy J. Kieran, Juliana DaSilva, Thomas J. Stark, Ian A. York, Claudia Pappas, John R. Barnes, Taronna R. Maines, Jessica A. Belser
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT While primarily considered a respiratory pathogen, influenza A virus (IAV) is nonetheless capable of spreading to, and replicating in, numerous extrapulmonary tissues in humans. However, within-host assessments of genetic diversity during mu
Externí odkaz:
https://doaj.org/article/ca453c11d6ca44df831d9437225bbd5f
Autor:
Christina P. Varian, Azael Saldaña, Jose E. Calzada, Fernando Abad‐Franch, Troy J. Kieran, Anchal Padukone, Jennifer K. Peterson, Nicole L. Gottdenker
Publikováno v:
Ecosphere, Vol 14, Iss 1, Pp n/a-n/a (2023)
Abstract Vector‐borne pathogen transmission is shaped by multiple abiotic and biotic factors. Understanding the relative importance of these factors on vector abundance and infection is important for developing vector‐borne disease control strate
Externí odkaz:
https://doaj.org/article/73e2ec46058146c6bf817fadeda70d08
Autor:
Joanna A. Pulit-Penaloza, Jessica A. Belser, Xiangjie Sun, Claudia Pappas, Nicole Brock, Troy J. Kieran, Jana M. Ritter, Josilene N. Seixas, Joyce Jones, Poulami Basu Thakur, Elizabeth Pusch, Li Wang, Terrence M. Tumpey, David E. Wentworth, Bin Zhou, Taronna R. Maines
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT The continued spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans necessitates evaluation of variants for enhanced virulence and transmission. We used the ferret model to perform a comparative analysis of four SA
Externí odkaz:
https://doaj.org/article/8b0bcee95c4d42dfb473b80e6866be3b