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Pembrolizumab activity in patients with Fanconi anemia repair pathway competent and deficient tumors
Autor:
Miguel A. Villalona-Calero, John P. Diaz, Wenrui Duan, Zuanel Diaz, Eric D. Schroeder, Santiago Aparo, Troy Gatcliffe, Federico Albrecht, Siddhartha Venkatappa, Victor Guardiola, Sara Garrido, Muni Rubens, Fernando DeZarraga, Hao Vuong
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Background Given the observed antitumor activity of immune-checkpoint-inhibitors in patients with mismatch-repair deficient (MSI-H) tumors, we hypothesized that deficiency in homologous-recombination-repair (HRR) can also influence susceptib
Externí odkaz:
https://doaj.org/article/638687a2c44a4b188f5880b1264f5ad8
Publikováno v:
Archives of Pathology & Laboratory Medicine. 144:918-919