Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Troy E. Metzger"'
Autor:
Troy E. Metzger, Chao Jiang, Stephanie Atencio, Christina M. Mailloux, Hilda L. Enriquez, Loren D. Erickson, María Rosa Bono, Trine N. Jørgensen, William M. Loo, Jennifer Alfaro, Mario Rosemblatt, Brian L. Kotzin, Shannon Flannery, Stephen J. Rozzo, Melanie R. Gubbels Bupp
Publikováno v:
JOURNAL OF IMMUNOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Autoantibodies are of central importance in the pathogenesis of Ab-mediated autoimmune disorders. The murine lupus susceptibility locus Nba2 on chromosome 1 and the syntenic human locus are associated with a loss of immune tolerance that leads to ant
Autor:
B. L. Kotzin, Michael T. Falta, Trine N. Jørgensen, Johne Kappler, Pilippa Marrack, S. A. Flannery, Troy E. Metzger, Shozo Izui, Joshua M. Thurman
Publikováno v:
Genes and Immunity, Vol. 7, No 7 (2006) pp. 555-567
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology. Associations between viral infections and the onset of SLE have been suggested, and recent studies have provided evidence that type I interferons (IFNalpha/beta) might p
Autor:
Troy E. Metzger, Heather Steele, Stephen J. Rozzo, Melanie R. Gubbels, Brian L. Kotzin, Shannon Flannery, Katherine Menze, Trine N. Jørgensen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(9)
The lupus-like disease that develops in hybrids of NZB and NZW mice is genetically complex, involving both MHC- and non-MHC-encoded genes. Studies in this model have indicated that the H2d/z MHC type, compared with H2d/d or H2z/z, is critical for dis
Autor:
Brian L. Kotzin, Fabienne Mackay, Bisram Deocharan, Dong Xu, Chaim Putterman, Trine N. Jørgensen, Christine Ambrose, Kyoung Soo Kim, Sarah A. Bixler, William Stohl, Susan L. Kalled, Troy E. Metzger, Yeon Sik Hong, Michael Koss, Laurence Morel
Publikováno v:
Arthritis and rheumatism. 52(7)
Objective To determine whether overexpression of BAFF can accelerate the development of systemic lupus erythematosus–associated end-organ disease in hosts with an underlying autoimmune diathesis. Methods We introduced a BAFF transgene (Tg) into aut
Publikováno v:
Arthritis and rheumatism. 50(7)
Objective To assess the effects of altered class II major histocompatibility complex (MHCII) expression on circulating autoantibody levels in C57BL/6 (B6) mice congenic for the Sle1 (B6.Sle1 mice) or Nba2 (B6.Nba2 mice) regions. Methods H-2Ab+/+ (MHC
Autor:
William Stohl, Dong Xu, Kyoung Soo Kim, Michael N. Koss, Trine N. Jorgensen, Bisram Deocharan, Troy E. Metzger, Sarah A. Bixler, Yeon Sik Hong, Christine M. Ambrose, Fabienne Mackay, Laurence Morel, Chaim Putterman, Brian L. Kotzin, Susan L. Kalled
Publikováno v:
Arthritis & Rheumatism; Jul2005, Vol. 52 Issue 7, p2080-2091, 12p
Publikováno v:
Arthritis & Rheumatism; Jul2004, Vol. 50 Issue 7, p2227-2239, 13p