Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Troy D, Ryba"'
Autor:
Troy D. Ryba, Maurice D. Lee, Stephen J. Haggarty, Surya A. Reis, Eamon Comer, Nathan T. Ross, Jingqiang Wei, Byung-Chul Suh, Michael Foley, Lakshmi B. Akella, Haibo Liu, Jason T. Lowe, Yan-Ling Zhang, Wen-Ning Zhao, Jeremy R. Duvall, Daniel M. Fass, Damian W. Young, Carol Mulrooney, Lisa A. Marcaurelle, Bhaumik A. Pandya, Ann Rowley, Michelle Palmer, Baudouin Gerard, Sivaraman Dandapani, Sarathy Kesavan, Jean-Charles Marie
Publikováno v:
Journal of the American Chemical Society. 132:16962-16976
An aldol-based ‘build/couple/pair’ (B/C/P) strategy was applied to generate a collection of stereochemically and skeletally diverse small molecules. In the build phase, a series of asymmetric syn- and anti- aldol reactions were performed to produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c575c3dd482cf0fdfd0443c446a3da8
https://doi.org/10.1021/ja105119r
https://doi.org/10.1021/ja105119r
Publikováno v:
Angewandte Chemie International Edition. 49:6151-6155
A convergent total synthesis of peloruside A (1) is described. The key strategic features are a diastereoselective lactonization to generate a C5-C9 valerolactone from the C2-symmetric ketone 4, which comprises C1–C9 of 1, and a relay ring closing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcdb8fc149279d82c6b95cd04c63c3a
https://doi.org/10.1002/anie.201002293
https://doi.org/10.1002/anie.201002293
Publikováno v:
Angewandte Chemie. 122:6287-6291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef0f1ac56f92dbb831e935a4811f4d6
https://doi.org/10.1002/ange.201002293
https://doi.org/10.1002/ange.201002293
Publikováno v:
Organic Letters. 7:2205-2208
The concentration of reactive metal hydride (Met-H) reducing agents can be determined (inor = 20 min) using No-D NMR spectroscopy. The method involves (i) reacting Met-H with an excess of p-methoxybenzaldehyde, (ii) quenching with excess acetic acid,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01ce488e6f64ec8e07b66613e29cb52
https://doi.org/10.1021/ol0506011
https://doi.org/10.1021/ol0506011
Publikováno v:
Organic Letters. 6:953-956
[reaction: see text] The title technique is a convenient and powerful method for directly monitoring or assaying any reaction mixture or reagent solution. Examples of some common processes (Fischer esterification, lithiation, butyllithium/THF compati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6fb9fd788f0f1826e166b259b9cde91
https://doi.org/10.1021/ol049979+
https://doi.org/10.1021/ol049979+
Autor:
Marie Harton, Carol A. Mulrooney, Michael Dombrowski, Sivaraman Dandapani, Troy D. Ryba, Bhaumik A. Pandya, Jeremy R. Duvall, Ann Rowley, Damian W. Young, Lisa A. Marcaurelle
Orthogonally protected chiral β-hydroxy-γ-amino acids can be accessed in >100 g quantities from readily available starting materials and reagents in 3-4 steps. These chiral synthons contain two adjacent stereocenters along with suitably protected f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e619990768c8d08db0d81ca04f16f169
https://europepmc.org/articles/PMC3150486/
https://europepmc.org/articles/PMC3150486/
Publikováno v:
Journal of combinatorial chemistry. 11(1)
The two-step functionalization of 30 000 SynPhase Polystyrene (PS) Lanterns in a 30-L glass process reactor is described. The first step involves bromination of the polystyrene backbone to afford an aryl bromide handle. Subsequent Suzuki cross coupli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ff5b551912d0b207d90fb9ba2e5feb
https://pubmed.ncbi.nlm.nih.gov/19049425
https://pubmed.ncbi.nlm.nih.gov/19049425
Publikováno v:
ChemInform. 37
A procedure is described for the in situ generation of functional equivalents of glutaric. succinic, and malonic dialdehydes. DIBAL-H reduction of the corresponding 1,n-dioates followed by in situ addition of a nucleophilic trapping agent allows for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077facdc9e9771d005a09554f5162e30
https://doi.org/10.1002/chin.200636060
https://doi.org/10.1002/chin.200636060
Publikováno v:
Organic letters. 6(6)
[reaction: see text] The title technique is a convenient and powerful method for directly monitoring or assaying any reaction mixture or reagent solution. Examples of some common processes (Fischer esterification, lithiation, butyllithium/THF compati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f84522030f355b3fc934d37e54a191e4
https://pubmed.ncbi.nlm.nih.gov/15012073
https://pubmed.ncbi.nlm.nih.gov/15012073
Publikováno v:
Synfacts. 2010:1331-1331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc91f463b987d5f5a1a5cfe8bb93da22
https://doi.org/10.1055/s-0030-1258876
https://doi.org/10.1055/s-0030-1258876