Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Troy C Lund"'
Autor:
Tina M Slusher, ProfMD, Hendrik J Vreman, PhD, Ann M Brearley, PhD, Yvonne E Vaucher, ProfMD, Ronald J Wong, BS, David K Stevenson, ProfMD, Olumide T Adeleke, MBBS, Ifelayo P Ojo, MPH, Grace Edowhorhu, FMLS, Troy C Lund, PhD, Daniel A Gbadero, MBBS
Publikováno v:
The Lancet Global Health, Vol 6, Iss 10, Pp e1122-e1131 (2018)
Summary: Background: Kernicterus resulting from severe neonatal hyperbilirubinaemia is a leading cause of preventable deaths and disabilities in low-income and middle-income countries, partly because high-quality intensive phototherapy is unavailable
Externí odkaz:
https://doaj.org/article/d297e5f8cce845858e54fc113d9f738c
Autor:
Yorrick R. J. Jaspers, Hemmo A. F. Yska, Caroline G. Bergner, Inge M. E. Dijkstra, Irene C. Huffnagel, Marije M. C. Voermans, Eric Wever, Gajja S. Salomons, Frédéric M. Vaz, Aldo Jongejan, Jill Hermans, Rebecca K. Tryon, Troy C. Lund, Wolfgang Köhler, Marc Engelen, Stephan Kemp
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-16 (2024)
Abstract Background X-linked adrenoleukodystrophy (ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1 resulting very long-chain fatty acids (VLCFA) accumulation in plasma and tissues. Males can present with various clinical mani
Externí odkaz:
https://doaj.org/article/d97e5ad3080540c59c9d92f89579ba8b
Autor:
Ericka G Jaramillo, Ezekiel Mupere, Robert O Opoka, James S Hodges, Troy C Lund, Michael K Georgieff, Chandy C John, Sarah E Cusick
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183977 (2017)
We evaluated the incidence of all-cause and malaria-specific clinic visits during follow-up of a recent trial of iron therapy. In the main trial, Ugandan children 6-59 months with smear-confirmed malaria and iron deficiency [zinc protoporphyrin (ZPP
Externí odkaz:
https://doaj.org/article/666ea1b81a9c45b2a2fd551526a71a9a
Autor:
Paul S Stadem, Megan V Hilgers, Derrick Bengo, Sarah E Cusick, Susan Ndidde, Tina M Slusher, Troy C Lund
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172980 (2017)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder that affects as many as 400 million people worldwide, making it the most common enzymatic defect. Subjects with G6PD deficiency are more likely to develop neonatal hyperbilir
Externí odkaz:
https://doaj.org/article/6a68d17eaf644c00bb755c8c43deb9ef
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113185 (2014)
Vitamin D plays an increasingly recognized role in the innate and adaptive immune response to infection. Based on demonstrated roles in up-regulating innate immunity, decreasing inflammation, and reducing the severity of disease in illnesses such as
Externí odkaz:
https://doaj.org/article/afcedd87125640f3b8f71f244d903cd9
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68800 (2013)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzymopathy and in Sub-Saharan Africa, is a significant cause of infection- and drug-induced hemolysis and neonatal jaundice. Our goals were to determine the prevalence of G
Externí odkaz:
https://doaj.org/article/ef2c83c1ac27422385b97580a6229e14
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73745 (2013)
Although exceptionally high radiation dose-rates are currently attaining clinical feasibility, there have been relatively few studies reporting the biological consequences of these dose-rates in hematopoietic cell transplant (HCT). In zebrafish model
Externí odkaz:
https://doaj.org/article/17eb2c9a0e5c4a169f4d3d307e06bc90
Autor:
Troy C Lund, Amanda J Kobs, Ashley Kramer, Mick Nyquist, Marcos T Kuroki, John Osborn, Diane S Lidke, Shalini T Low-Nam, Bruce R Blazar, Jakub Tolar
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58945 (2013)
The ability of cells to detect changes in the microenvironment is important in cell signaling and responsiveness to environmental fluctuations. Our interest is in understanding how human bone marrow stromal-derived cells (MSC) and their relatives, va
Externí odkaz:
https://doaj.org/article/d7fc5c7d85da45d1a727b6acf791b772
Autor:
Troy C Lund, Paul S Stadem, Angela Panoskaltsis-Mortari, Gerald Raymond, Weston P Miller, Jakub Tolar, Paul J Orchard
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32218 (2012)
BackgroundX-linked adrenoleukodystrophy (ALD) is a metabolic, peroxisomal disease that results from a mutation in the ABCD1 gene. The most severe course of ALD progression is the cerebral inflammatory and demyelinating form of the disease, cALD. To d
Externí odkaz:
https://doaj.org/article/54b0c4fa51ac4e8bb4b17460f9972de5
Autor:
Kathryn A Thibert, Gerald V Raymond, David R Nascene, Weston P Miller, Jakub Tolar, Paul J Orchard, Troy C Lund
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50430 (2012)
X-linked adrenoleukodystrophy results from mutations in the ABCD1 gene disrupting the metabolism of very-long-chain fatty acids. The most serious form of ALD, cerebral adrenoleukodystrophy (cALD), causes neuroinflammation and demyelination. Neuroimag
Externí odkaz:
https://doaj.org/article/ed5bc9d739fa49a28aa2472305bae472