Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Troy Bankhead"'
Publikováno v:
Pathogens, Vol 13, Iss 6, p 487 (2024)
The bacterial agent of Lyme disease, Borrelia burgdorferi, exists in an enzootic cycle by adapting to dissimilar mammalian and tick environments. The genetic elements necessary for host and vector adaptation are spread across a bacterial genome compr
Externí odkaz:
https://doaj.org/article/391142d80ac141d2ae3f4c4966c50d48
Autor:
Michael A. Crowley, Troy Bankhead
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The bacterial agent of Lyme disease, Borrelia burgdorferi, relies on an intricate gene regulatory network to transit between the disparate Ixodes tick vector and mammalian host environments. We recently reported that a B. burgdorferi mutant lacking a
Externí odkaz:
https://doaj.org/article/99843995a07e4257a69e4507eae0a950
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Borrelia burgdorferi, the Lyme disease pathogen, is maintained in its enzootic life cycle through complex gene regulatory pathways encoded on its uniquely fragmented genome. This genome consists of over 20 plasmids, and the regulatory mechanisms of p
Externí odkaz:
https://doaj.org/article/cf51cbbb3b824bbb84d4cf9cac6152b8
Autor:
Sam T. Donta, Leith J. States, Wendy A. Adams, Troy Bankhead, Nicole Baumgarth, Monica E. Embers, Robert B. Lochhead, Brian Stevenson
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis
Externí odkaz:
https://doaj.org/article/e67b6010a66548ae8ddc98a3e67e583f
Autor:
Abdul G. Lone, Troy Bankhead
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3663-3670.e5 (2020)
Summary: Arp is an immunogenic protein of the Lyme disease spirochete Borrelia burgdorferi and contributes to joint inflammation during infection. Despite Arp eliciting a strong humoral response, antibodies fail to clear the infection. Given previous
Externí odkaz:
https://doaj.org/article/9e90d2371c604ebcb9698806c587352a
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155798 (2016)
DNA methyltransferases have been implicated in the regulation of virulence genes in a number of pathogens. Relapsing fever Borrelia species harbor a conserved, putative DNA methyltransferase gene on their chromosome, while no such ortholog can be fou
Externí odkaz:
https://doaj.org/article/ad8c0d62a6d943bb96e86b580fb612fd
Autor:
Artem S Rogovskyy, Timothy Casselli, Yvonne Tourand, Cami R Jones, Jeb P Owen, Kathleen L Mason, Glen A Scoles, Troy Bankhead
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124268 (2015)
Efficient acquisition and transmission of Borrelia burgdorferi by the tick vector, and the ability to persistently infect both vector and host, are important elements for the life cycle of the Lyme disease pathogen. Previous work has provided strong
Externí odkaz:
https://doaj.org/article/d019bf6248dd4eba9d7b700a6cca12c2
Autor:
Artem S Rogovskyy, Troy Bankhead
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61226 (2013)
Many pathogens make use of antigenic variation as a way to evade the host immune response. A key mechanism for immune evasion and persistent infection by the Lyme disease spirochete, Borrelia burgdorferi, is antigenic variation of the VlsE surface pr
Externí odkaz:
https://doaj.org/article/6e9447d814124e5e95b7afe2c28f3b69
Publikováno v:
PLoS Pathogens, Vol 4, Iss 6, p e1000090 (2008)
Pathogenic spirochetes are bacteria that cause a number of emerging and re-emerging diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis. They navigate efficiently through dense extracellular matrix and cross t
Externí odkaz:
https://doaj.org/article/4964ec69776245e59909e226ad196f9f
Autor:
Troy Bankhead, Nicole Baumgarth, Brian Stevenson, Wendy A. Adams, Robert B. Lochhead, Monica E. Embers, Sam T. Donta, Leith J. States
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine, Vol 8 (2021)
An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d4970376c13574819f524c9395cf93
http://europepmc.org/articles/PMC8215209
http://europepmc.org/articles/PMC8215209