Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Troy A Harkness"'
Autor:
Zheng Hu, Bo Xia, Spike DL Postnikoff, Zih-Jie Shen, Alin S Tomoiaga, Troy A Harkness, Ja Hwan Seol, Wei Li, Kaifu Chen, Jessica K Tyler
Publikováno v:
eLife, Vol 7 (2018)
Translational efficiency correlates with longevity, yet its role in lifespan determination remains unclear. Using ribosome profiling, translation efficiency is globally reduced during replicative aging in budding yeast by at least two mechanisms: Fir
Externí odkaz:
https://doaj.org/article/f4bd1d018dd843abad7bcb3c16a77f25
Autor:
Ata Ghavidel, Kunal Baxi, Martin Prusinkiewicz, Cynthia Swan, Zach R. Belak, Christopher H. Eskiw, Carlos E. Carvalho, Troy A. Harkness
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1579-1592 (2018)
The yeast, Saccharomyces cerevisiae, like other higher eukaryotes, undergo a finite number of cell divisions before exiting the cell cycle due to the effects of aging. Here, we show that yeast aging begins with the nuclear exclusion of Hcm1 in young
Externí odkaz:
https://doaj.org/article/5102f45718a241e8b263a725b4e00d9f
Autor:
Rubin Jiao, Liubov Lobanova, Amanda Waldner, Anthony Fu, Linda Xiao, Troy A. Harkness, Terra G. Arnason
Publikováno v:
Microbial Cell, Vol 3, Iss 11, Pp 540-553 (2016)
The SNF1 kinase in Saccharomyces cerevisiae is an excellent model to study the regulation and function of the AMP-dependent protein kinase (AMPK) family of serine-threonine protein kinases. Yeast discoveries regarding the regulation of this non-hormo
Externí odkaz:
https://doaj.org/article/17cbe6117c364b14a28b23abd75eaf3e
Publikováno v:
Drug Design, Development and Therapy, Vol 2009, Iss default, Pp 79-88 (2009)
Gerald F Davies1, Bernhard HJ Juurlink2, Troy AA Harkness11Department of Anatomy and Cell Biology, College of Medicine, University of Saskatchewan, Saskatoon, Canada; 2College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi ArabiaAbstract:
Externí odkaz:
https://doaj.org/article/1ed2a8004aa940a78382401e4b2297e0
Antagonistic Gcn5-Hda1 interactions revealed by mutations to the Anaphase Promoting Complex in yeast
Publikováno v:
Cell Division
Cell Division, Vol 6, Iss 1, p 13 (2011)
Cell Division, Vol 6, Iss 1, p 13 (2011)
BackgroundHistone post-translational modifications are critical for gene expression and cell viability. A broad spectrum of histone lysine residues have been identified in yeast that are targeted by a variety of modifying enzymes. However, the regula