Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Troy, Stevens"'
Autor:
Navneet Singh, Carsten Eickhoff, Augusto Garcia-Agundez, Paul Bertone, Sunita S. Paudel, Dhananjay T. Tambe, Leslie A. Litzky, Katherine Cox-Flaherty, James R. Klinger, Sean F. Monaghan, Christopher J. Mullin, Mandy Pereira, Thomas Walsh, Mary Whittenhall, Troy Stevens, Elizabeth O. Harrington, Corey E. Ventetuolo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes,
Externí odkaz:
https://doaj.org/article/fe02a15d8bc348fbaf794a7a71a2d29c
Autor:
Phoibe Renema, Jean-Francois Pittet, Angela P Brandon, Sixto M Leal, Steven Gu, Grace Promer, Andrew Hackney, Phillip Braswell, Andrew Pickering, Grace Rafield, Sarah Voth, Ron Balczon, Mike T Lin, K Adam Morrow, Jessica Bell, Jonathon P Audia, Diego Alvarez, Troy Stevens, Brant M Wagener
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298816 (2024)
BackgroundBacterial pneumonia and sepsis are both common causes of end-organ dysfunction, especially in immunocompromised and critically ill patients. Pre-clinical data demonstrate that bacterial pneumonia and sepsis elicit the production of cytotoxi
Externí odkaz:
https://doaj.org/article/7e24ba0ec0fc45c7b6da14ffbca953db
Autor:
Ron Balczon, Kyle A. Morrow, Silas Leavesley, Christopher M. Francis, Trevor C. Stevens, Ezinne Agwaramgbo, Christopher Williams, Reece P. Stevens, Geri Langham, Sarah Voth, Eugene A. Cioffi, Susan E. Weintraub, Troy Stevens
Publikováno v:
FEBS Open Bio, Vol 10, Iss 11, Pp 2464-2477 (2020)
Infection of rat pulmonary microvascular endothelial cells with the bacterium Pseudomonas aeruginosa induces the production and release of cytotoxic oligomeric tau and beta amyloid (Aβ). Here, we characterized these cytotoxic amyloids. Cytotoxic beh
Externí odkaz:
https://doaj.org/article/3cdc32ec572c4bfbb3f4d01d03b3fc1a
Autor:
Ningyong Xu, Linn Ayers, Viktoriya Pastukh, Mikhail Alexeyev, Troy Stevens, Dhananjay T Tambe
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250095 (2021)
Collective migration of endothelial cells is important for wound healing and angiogenesis. During such migration, each constituent endothelial cell coordinates its magnitude and direction of migration with its neighbors while retaining intercellular
Externí odkaz:
https://doaj.org/article/236f15db273a4cc98e7bc0419fc5a591
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension is a fatal disease, where death is associated with right heart failure and reduced cardiorespiratory reserve. The Sugen 5416, hypoxia and normoxia Fischer rat model mimics human pulmonary arterial hypertension, althoug
Externí odkaz:
https://doaj.org/article/41f3ed03a42b4cca8a5e1dba4f468d1d
Autor:
Kierra S. Hardy, Amanda N. Tuckey, Phoibe Renema, Mita Patel, Abu-Bakr Al-Mehdi, Domenico Spadafora, Cody A. Schlumpf, Robert A. Barrington, Mikhail F. Alexeyev, Troy Stevens, Jean-Francois Pittet, Brant M. Wagener, Jon D. Simmons, Diego F. Alvarez, Jonathon P. Audia
Publikováno v:
Toxins, Vol 14, Iss 2, p 152 (2022)
The Gram-negative, opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system to inject exoenzyme effectors into a target host cell. Of the four best-studied exoenzymes, ExoU causes rapid cell damage and death. ExoU is a phosp
Externí odkaz:
https://doaj.org/article/c9f84dac36d44282a31de0221c698954
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C936-C949
The pulmonary artery endothelium forms a semipermeable barrier that limits macromolecular flux through intercellular junctions. This barrier is maintained by an intrinsic forward protrusion of the interacting membranes between adjacent cells. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73177b68e50b34c1d25cf66bd625aee
https://doi.org/10.1152/ajpcell.00339.2021
https://doi.org/10.1152/ajpcell.00339.2021
Autor:
Reece P. Stevens, Mikhail F. Alexeyev, Natalia Kozhukhar, Viktoria Pastukh, Sunita S. Paudel, Jessica Bell, Dhananjay T. Tambe, Troy Stevens, Ji Young Lee
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
The lungs of patients with acute respiratory distress syndrome (ARDS) have hyperpermeable capillaries that must undergo repair in an acidic microenvironment. Pulmonary microvascular endothelial cells (PMVECs) have an acid-resistant phenotype, in part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4d9b7894d8e223421e706d2b7e018d
https://doi.org/10.1152/ajplung.00337.2021
https://doi.org/10.1152/ajplung.00337.2021
Autor:
William J. Cleveland, Josephine E. Hees, Claudius Balzer, Hunter F. Douglas, Troy Stevens, Matthias L. Riess
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe66039e8c46301c0dab40cd3baa8892
https://doi.org/10.3791/64740
https://doi.org/10.3791/64740
Autor:
Ji Young Lee, Reece P. Stevens, Viktoriya V Pastukh, Viktor M Pastukh, Natalya Kozhukhar, Mikhail F. Alexeyev, Julie A Reisz, David Nerguizian, Angelo D'Alessandro, Anna Koloteva, Meredith S. Gwin, Justin T Roberts, Glen M Borchert, Brant M. Wagener, Jean-François Pittet, Brian B Graham, Kurt R Stenmark, Troy Stevens
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf646eec6d252b885a30f92f1fd7d541
https://doi.org/10.1165/rcmb.2022-0443oc
https://doi.org/10.1165/rcmb.2022-0443oc