Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Tropomyosin kinase"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 3992 (2024)
Tropomyosin kinase receptor B (TrkB) has been explored as a therapeutic target for neurological and psychiatric disorders. However, the development of TrkB agonists was hindered by our poor understanding of the TrkB agonist binding location and affin
Externí odkaz:
https://doaj.org/article/590fb702e0d34603a7b1cdd736c75b11
Akademický článek
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Autor:
Qianli Wang, Yong Zhao, Xin Dong, Cong Li, Lin Zhou, Chengwei Zou, Xiaodong Li, Nannan Zhou, Junni Liu, Yuanyuan Sun, Jianchun Wang
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 12, Pp 1379-1386 (2021)
Objective Nerve growth factor (NGF) and tropomyosin kinase receptors A (TrKA) exert a crucial effect on the regulation of autonomic nervous system which contributes to the progress of atrial fibrillation (AF). Valvular heart disease (VHD) patients ar
Externí odkaz:
https://doaj.org/article/6056bbdbeeed43d2a5148423e95e7cb5
Autor:
Ge Li, Bao Zhang, Jia-hui Sun, Li-yang Shi, Meng-yao Huang, Li-jun Huang, Zi-jing Lin, Qiong-yu Lin, Bi-qin Lai, Yuan-huan Ma, Bin Jiang, Ying Ding, Hong-bo Zhang, Miao-xin Li, Ping Zhu, Ya-qiong Wang, Xiang Zeng, Yuan-shan Zeng
Publikováno v:
Bioactive Materials, Vol 6, Iss 11, Pp 3766-3781 (2021)
The mechanism underlying neurogenesis during embryonic spinal cord development involves a specific ligand/receptor interaction, which may be help guide neuroengineering to boost stem cell-based neural regeneration for the structural and functional re
Externí odkaz:
https://doaj.org/article/f0bfc344f9fa4db5a13cab39f61eb7e5
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Tracey Williams, Rajendran Vairagoundar, Julie A. White, Dennis L Huczek, Respondek Tomasz, Jason T. Ross, Johnson Paul D, Carolyn Hedke, Andrea J Gonzales, Govindan Subramanian, Christopher Javens, Todd Maddux, Brian A. Duclos, Theresa Zachary, Mark R Cox, Wendy Collard, Yaqi Zhu, Steven Kamerling, Scott J. Bowen
Publikováno v:
ACS Medicinal Chemistry Letters. 12:1847-1852
Human β-nerve growth factor (β-NGF) and its associated receptor, human tropomyosin receptor kinase A (hTrkA), have been demonstrated to be key factors in the perception of pain. However, efficacious small molecule therapies targeting the intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6630b824f3daa850025a3853fdae724
https://doi.org/10.1021/acsmedchemlett.1c00483
https://doi.org/10.1021/acsmedchemlett.1c00483
Autor:
Bi-Qin Lai, Yuan-Huan Ma, Bao Zhang, Ya-Qiong Wang, Xiang Zeng, Zi-jing Lin, Ge Li, Miao-xin Li, Li-yang Shi, Ying Ding, Qiong-yu Lin, Yuan-Shan Zeng, Bin Jiang, Meng-Yao Huang, Hong-bo Zhang, Jia-Hui Sun, Li-Jun Huang, Ping Zhu
Publikováno v:
Bioactive Materials
Bioactive Materials, Vol 6, Iss 11, Pp 3766-3781 (2021)
Bioactive Materials, Vol 6, Iss 11, Pp 3766-3781 (2021)
The mechanism underlying neurogenesis during embryonic spinal cord development involves a specific ligand/receptor interaction, which may be help guide neuroengineering to boost stem cell-based neural regeneration for the structural and functional re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d064833c1088eefee586cf8da9381
http://europepmc.org/articles/PMC8044869
http://europepmc.org/articles/PMC8044869
Autor:
Fabricio T Romagnol, Eliana M Caran, Sérgio Cavalheiro, Marcelo de Toledo Petrilli, Henrique Manoel Lederman, Fernanda Teresa de Lima, Maria Teresa de Seixas Alves, Leticia Yasuda Carreira, Antonio Sérgio Petrilli
Publikováno v:
Clinical Oncology and Research. :1-6
This case report describes the outcomes of tropomyosin receptor kinase (TRK) inhibitor treatment in an infant with an infantile fibrosarcoma (IFS) with a TPM3–NTRK1 gene fusion. The IFS on the left foot was refractory to chemotherapy and was partia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12081ac71da64ec7eb6e9f0542d8380
https://doi.org/10.31487/j.cor.2021.03.03
https://doi.org/10.31487/j.cor.2021.03.03
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10249
The activation of tropomyosin receptor kinase B (TrkB), the receptor of brain-derived neurotrophic factor (BDNF), plays a key role in induced juvenile-like plasticity (iPlasticity), which allows restructuring of neural networks in adulthood. Opticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813d1077057f5aea76089152c25f6525
https://pubmed.ncbi.nlm.nih.gov/36142154
https://pubmed.ncbi.nlm.nih.gov/36142154
Publikováno v:
Molecular Medicine Reports
Optogenetics combined with protein engineering based on natural light‑sensitive dimerizing proteins has evolved as a powerful strategy to study cellular functions. The present study focused on tropomyosin kinase receptors (Trks) that have been engi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b79e66fd6d55ca22b0a31e38701d378
http://europepmc.org/articles/PMC8767455
http://europepmc.org/articles/PMC8767455