Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Trophoblast differentiation"'
Publikováno v:
Organoids, Vol 3, Iss 3, Pp 174-193 (2024)
First trimester placental development comprises some of the most critical yet understudied events that impact fetal development. Improper placentation leads to a host of health issues that not only impact the fetal period but also influence offspring
Externí odkaz:
https://doaj.org/article/af2ff85bb2624a9a81e2cb8d6304e50f
Autor:
Bai-Mei Zhuang, Dan-Dan Cao, Tian-Xi Li, Xiao-Feng Liu, Min-Min Lyu, Si-Dong Wang, Xin-Yuan Cui, Li Wang, Xiao-Lin Chen, Xiao-Li Lin, Cheuk-Lun Lee, Philip C.N. Chiu, William S.B. Yeung, Yuan-Qing Yao
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Extravillous trophoblast cell (EVT) differentiation and its communication with maternal decidua especially the leading immune cell type natural killer (NK) cell are critical events for placentation. However, appropriate in vitro m
Externí odkaz:
https://doaj.org/article/9896094096ac49c888855cc0e2f4137f
Autor:
Chien-Chu Huang, Ya-Wen Hsueh, Chia-Wei Chang, Hsi-Chen Hsu, Tung-Chuan Yang, Wu-Chou Lin, Hsun-Ming Chang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Early pregnancy is a complex and well-orchestrated differentiation process that involves all the cellular elements of the fetal-maternal interface. Aberrant trophoblast-decidual interactions can lead to miscarriage and disorders that occur later in p
Externí odkaz:
https://doaj.org/article/e60536f72a8c485abba81241d9b20a70
Autor:
Andy Chun Hang Chen, Yin Lau Lee, Hanzhang Ruan, Wen Huang, Sze Wan Fong, Siyu Tian, Kai Chuen Lee, Genie Minju Wu, Yongqi Tan, Timothy Chun Hin Wong, Jian Wu, Weiyu Zhang, Dandan Cao, Judy Fung Cheung Chow, Pengtao Liu, William Shu Biu Yeung
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Human expanded potential stem cells (hEPSC) have been derived from human embryonic stem cells and induced pluripotent stem cells. Here direct derivation of hEPSC from human pre‐implantation embryos is reported. Like the reported hEPSC, the
Externí odkaz:
https://doaj.org/article/f94f3373081d41d3ac0c4b6056104e39
Autor:
Bai-Mei Zhuang, Dan-Dan Cao, Xiao-Feng Liu, Li Wang, Xiao-Li Lin, Yong-Gang Duan, Cheuk-Lun Lee, Philip C. N. Chiu, William S. B. Yeung, Yuan-Qing Yao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The human placenta is a unique temporary organ with a mysterious immune tolerance. The formation of trophoblast organoids has advanced the study of placental development. HLA-G is uniquely expressed in the extravillous trophoblast (EVT) and has been
Externí odkaz:
https://doaj.org/article/f528649c194348db8cddd91da0773daa
Akademický článek
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Publikováno v:
Nutrients, Vol 15, Iss 16, p 3564 (2023)
Placental development is a tightly controlled event, in which cell expansion from the trophectoderm occurs in a spatiotemporal manner. Proper trophoblast differentiation is crucial to the vitality of this gestational organ. Obstructions to its develo
Externí odkaz:
https://doaj.org/article/bd03fcb38bad49f0a393589b526ae006
Autor:
Yiming Wang, Xiangxiang Jiang, Lei Jia, Xulun Wu, Hao Wu, Yue Wang, Qian Li, Ruoxuan Yu, Hongmei Wang, Zhenyu Xiao, Xiaoyan Liang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Implantation of the human blastocyst is a milestone event in embryonic development. The trophoblast is the first cell lineage to differentiate during implantation. Failures in trophoblast differentiation during implantation are correlated to the defe
Externí odkaz:
https://doaj.org/article/037cbec3e90d45308fbf93efb797da03
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Preeclampsia (PE) occurs only in humans and some non‐human primates, making its pathogenesis difficult to study. The aetiology of PE is mainly caused by a deficiency in trophoblast differentiation and spiral artery remodelling. The angioge
Externí odkaz:
https://doaj.org/article/f4d8ad2a4dc74c6eb11ee63066bfc936
Autor:
Yukako Kayashima, W. H. Davin Townley-Tilson, Neeta L. Vora, Kim Boggess, Jonathon W. Homeister, Nobuyo Maeda-Smithies, Feng Li
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2149 (2023)
Obesity is a risk factor for preeclampsia. We investigated how obesity influences preeclampsia in mice lacking ankyrin-repeat-and-SOCS-box-containing-protein 4 (ASB4), which promotes trophoblast differentiation via degrading the inhibitor of DNA-bind
Externí odkaz:
https://doaj.org/article/66cc9aa8ecdb463dafe2600ddd17d9d3