In vivo multiphoton-microscopy of picosecond-laser-induced optical breakdown in human skin

Autor: Balu, M, Lentsch, G, Korta, DZ, König, K, Kelly, KM, Tromberg, BJ, Zachary, CB

Publikováno v: Balu, M; Lentsch, G; Korta, DZ; König, K; Kelly, KM; Tromberg, BJ; et al.(2017). In vivo multiphoton-microscopy of picosecond-laser-induced optical breakdown in human skin. Lasers in Surgery and Medicine, 49(6), 555-562. doi: 10.1002/lsm.22655. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2xp2s3zv

© 2017 Wiley Periodicals, Inc. Importance: Improvements in skin appearance resulting from treatment with fractionated picosecond-lasers have been noted, but optimizing the treatment efficacy depends on a thorough understanding of the specific skin r

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Cell and brain tissue imaging of the flavonoid fisetin using label-free two-photon microscopy

Autor: Krasieva, TB, Ehren, J, O'Sullivan, T, Tromberg, BJ, Maher, P

Publikováno v: Krasieva, TB; Ehren, J; Ehren, J; O'Sullivan, T; Tromberg, BJ; & Maher, P. (2015). Cell and brain tissue imaging of the flavonoid fisetin using label-free two-photon microscopy. Neurochemistry International. doi: 10.1016/j.neuint.2015.08.003. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7zv9n02s

© 2015 Elsevier Ltd. Over the last few years, we have identified an orally active, novel neuroprotective and cognition-enhancing molecule, the flavonoid fisetin. Fisetin not only has direct antioxidant activity but it can also increase the intracell

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Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy

Autor: Balu, M, Kelly, KM, Zachary, CB, Harris, RM, Krasieva, TB, König, K, Durkin, AJ, Tromberg, BJ

Publikováno v: Cancer research, vol 74, iss 10
Balu, M; Kelly, KM; Zachary, CB; Harris, RM; Krasieva, TB; König, K; et al.(2014). Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy. Cancer Research, 74(10), 2688-2697. doi: 10.1158/0008-5472.CAN-13-2582. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/84m3196c

Monitoring of atypical nevi is an important step in early detection of melanoma, a clinical imperative in preventing the disease progression. Current standard diagnosis is based on biopsy and histopathologic examination, a method that is invasive and

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Monitoring cerebral tissue oxygen saturation during surgery: A clinician's perspective

Autor: Meng, L, Gelb, AW, Cerussi, AE, Mantulin, WW, Tromberg, BJ

Publikováno v: Meng, L; Gelb, AW; Cerussi, AE; Mantulin, WW; & Tromberg, BJ. (2013). Monitoring cerebral tissue oxygen saturation during surgery: A clinician's perspective. Progress in Biomedical Optics and Imaging-Proceedings of SPIE, 8578. doi: 10.1117/12.2014090. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4h53p9q4

Organ protection and physiology optimization are important goals when taking care of anesthetized patients undergoing surgery. Postoperative cognitive dysfunction and perioperative stroke are unwarranted potential outcomes. Neurovascular coupling, th

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First-in-human pilot study of a spatial frequency domain oxygenation imaging system

Autor: Gioux, S, Mazhar, A, Lee, BT, Lin, SJ, Tobias, AM, Cuccia, DJ, Stockdale, A, Oketokoun, R, Ashitate, Y, Kelly, E, Weinmann, M, Durr, NJ, Moffitt, LA, Durkin, AJ, Tromberg, BJ, Frangionia, JV

Publikováno v: Gioux, S; Mazhar, A; Lee, BT; Lin, SJ; Tobias, AM; Cuccia, DJ; et al.(2011). First-in-human pilot study of a spatial frequency domain oxygenation imaging system. Journal of Biomedical Optics, 16(8). doi: 10.1117/1.3614566. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8933r3gv

Oxygenation measurements are widely used in patient care. However, most clinically available instruments currently consist of contact probes that only provide global monitoring of the patient (e.g., pulse oximetry probes) or local monitoring of small

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