Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Troels Bo Thomsen"'
Publikováno v:
Thomsen, T B, Li, L & Howard, K 2014, ' Mucus barrier-triggered disassembly of siRNA nanocarriers ', Nanoscale, vol. 6, no. 21, pp. 12547-54 . https://doi.org/10.1039/c4nr01584c
The mucus overlying mucosal epithelial surfaces presents not only a biological barrier to the penetration of potential pathogens, but also therapeutic modalities including RNAi-based nanocarriers. Movement of nanomedicines across the mucus barriers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4519e3c5703c87bb59a1adbf88ba8349
https://doi.org/10.1039/c4nr01584c
https://doi.org/10.1039/c4nr01584c
Publikováno v:
Drug Delivery and Translational Research
Gonzalez, B B, Thomsen, T B & Howard, K 2013, ' Clinical translation of RNAi-based treatments for respiratory diseases ', Drug Delivery and Translational Research, vol. 3, no. 1, pp. 84-99 . https://doi.org/10.1007/s13346-012-0098-7
Gonzalez, B B, Thomsen, T B & Howard, K 2013, ' Clinical translation of RNAi-based treatments for respiratory diseases ', Drug Delivery and Translational Research, vol. 3, no. 1, pp. 84-99 . https://doi.org/10.1007/s13346-012-0098-7
The ability to harness the RNA interference (RNAi) mechanism as a potential potent therapeutic has attracted great interest from academia and industry. Numerous preclinical and recent clinical trials have demonstrated the effectiveness of RNAi trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8a935b91f67dde8cd70dfbc636aee0
https://pubmed.ncbi.nlm.nih.gov/25787868
https://pubmed.ncbi.nlm.nih.gov/25787868
Publikováno v:
Advances in Delivery Science and Technology ISBN: 9781461447436
Gonzalez, B B, Nielsen, E J B, Thomsen, T B & Howard, K 2013, Mucosal Delivery of RNAi Therapeutics . in K A Howard (ed.), RNA Interference from Biology to Therapeutics . Springer, Advances in Delivery Science and Technology, pp. 97-125 . < http://link.springer.com/chapter/10.1007%2F978-1-4614-4744-3_5#page-1 >
Gonzalez, B B, Nielsen, E J B, Thomsen, T B & Howard, K 2013, Mucosal Delivery of RNAi Therapeutics . in K A Howard (ed.), RNA Interference from Biology to Therapeutics . Springer, Advances in Delivery Science and Technology, pp. 97-125 . < http://link.springer.com/chapter/10.1007%2F978-1-4614-4744-3_5#page-1 >
The effectiveness of RNA interference-based drugs is dependent on accumulation at the target site in therapeutically relevant amounts. Local administration to the mucosal surfaces lining the respiratory, gastrointestinal and genitourinary tracts allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0bc07944d09180d2d794887d0e9471
https://doi.org/10.1007/978-1-4614-4744-3_5
https://doi.org/10.1007/978-1-4614-4744-3_5
