Zobrazeno 1 - 10
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pro vyhledávání: '"Troast DM"'
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Akademický článek
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Akademický článek
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Autor:
Harrison BA; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Dowling JE; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Bursavich MG; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Troast DM; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Chong KM; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Hahn KN; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Zhong C; Chemistry, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Mulvihill KM; CMC, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Nguyen H; CMC, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Monroy MF; Molecular and Cellular Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Qiao Q; Molecular and Cellular Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Sosa B; Molecular and Cellular Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Mostafavi S; Molecular and Cellular Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Smukste I; DMPK, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Lee D; DMPK, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Cappellucci L; Screening Biology, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Konopka EH; Screening Biology, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Nowakowski P; Screening Biology, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Stawski L; Fibrosis, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Senices M; Fibrosis, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Nguyen MH; Fibrosis, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Kapoor PS; Fibrosis, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Luus L; Translational Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Sullivan A; Translational Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Bortolato A; Computational Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Svensson M; Computational Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Hickey ER; Medicinal Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Konze KD; Medicinal Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Day T; Computational Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Kim B; Computational Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Negri A; Computational Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Gerasyuto AI; Medicinal Chemistry, Therapeutics Group, Schrödinger, New York, New York 10036, United States., Moy TI; Screening Biology, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Lu M; Fibrosis, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Ray AS; Biology and Translational Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Wang L; Biology and Translational Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Cui D; DMPK, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Lin FY; Molecular and Cellular Sciences, Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Lippa B; Morphic Therapeutic, Waltham, Massachusetts 02451, United States., Rogers BN; Morphic Therapeutic, Waltham, Massachusetts 02451, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Oct 24. Date of Electronic Publication: 2024 Oct 24.
Autor:
Buskes MJ; Atavistik Bio 75 Sidney Street, Cambridge, Massachusetts 02139, United States., Coffin A; Atavistik Bio 75 Sidney Street, Cambridge, Massachusetts 02139, United States., Troast DM; Atavistik Bio 75 Sidney Street, Cambridge, Massachusetts 02139, United States., Stein R; Atavistik Bio 75 Sidney Street, Cambridge, Massachusetts 02139, United States., Blanco MJ; Atavistik Bio 75 Sidney Street, Cambridge, Massachusetts 02139, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Mar 08; Vol. 14 (4), pp. 376-385. Date of Electronic Publication: 2023 Mar 08 (Print Publication: 2023).
Autor:
Ryan MD; X-Biotix Therapeutics, 465 Waverly Oaks Road, Waltham, Massachusetts 02452, United States., Parkes AL; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Corbett D; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Dickie AP; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Southey M; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Andersen OA; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Stein DB; Evotec SE, Manfred Eigen Campus, Essener Bogen 7, 22419 Hamburg, Germany., Barbeau OR; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Sanzone A; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Thommes P; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Barker J; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Cain R; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Compper C; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Dejob M; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Dorali A; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Etheridge D; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Evans S; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Faulkner A; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Gadouleau E; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Gorman T; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Haase D; Evotec SE, Manfred Eigen Campus, Essener Bogen 7, 22419 Hamburg, Germany., Holbrow-Wilshaw M; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Krulle T; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Li X; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Lumley C; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Mertins B; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Napier S; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Odedra R; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Papadopoulos K; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Roumpelakis V; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Spear K; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Trimby E; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Williams J; Evotec UK, Anti-infectives, Block 23F, Alderley Park, Cheshire SK10 4TG, U.K., Zahn M; Evotec, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Keefe AD; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Soutter HT; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Centrella PA; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Clark MA; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Cuozzo JW; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Dumelin CE; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Deng B; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Hunt A; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Sigel EA; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., Troast DM; X-Chem, 100 Beaver Street, Waltham, Massachusetts 02453, United States., DeJonge BLM; X-Biotix Therapeutics, 465 Waverly Oaks Road, Waltham, Massachusetts 02452, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Oct 14; Vol. 64 (19), pp. 14377-14425. Date of Electronic Publication: 2021 Sep 27.
Autor:
Miller EB; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Murphy RB; Schrödinger, Inc., 10201 Wateridge Circle, San Diego, California 92121, United States., Sindhikara D; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Borrelli KW; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Grisewood MJ; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Ranalli F; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Dixon SL; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Jerome S; Schrödinger, Inc., 10201 Wateridge Circle, San Diego, California 92121, United States., Boyles NA; Schrödinger, Inc., 101 SW Main Street, Portland, Oregon 97204, United States., Day T; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Ghanakota P; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Mondal S; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Rafi SB; Schrödinger, Inc., 101 SW Main Street, Portland, Oregon 97204, United States., Troast DM; Morphic Therapeutic, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Abel R; Schrödinger, Inc., 120 West 45th Street, New York, New York 10036, United States., Friesner RA; Department of Chemistry, Columbia University, 3000 Broadway, MC 3110, New York, New York 10036, United States.
Publikováno v:
Journal of chemical theory and computation [J Chem Theory Comput] 2021 Apr 13; Vol. 17 (4), pp. 2630-2639. Date of Electronic Publication: 2021 Mar 29.
Autor:
Brown DG; 1 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Waltham, MA, USA., Brown GA; 2 Heptares Therapeutics Ltd., Welwyn Garden City, Hertfordshire, UK., Centrella P; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Certel K; 3 X-Chem Pharmaceuticals, Waltham, MA, USA.; 5 Novartis Institute for BioMedical Research, Cambridge, MA, USA., Cooke RM; 2 Heptares Therapeutics Ltd., Welwyn Garden City, Hertfordshire, UK., Cuozzo JW; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Dekker N; 4 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Mölndal, Sweden., Dumelin CE; 3 X-Chem Pharmaceuticals, Waltham, MA, USA.; 6 Novartis Institute for BioMedical Research, Basel, Switzerland., Ferguson A; 1 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Waltham, MA, USA.; 7 X-Chem, Inc., Waltham, MA, USA., Fiez-Vandal C; 2 Heptares Therapeutics Ltd., Welwyn Garden City, Hertfordshire, UK., Geschwindner S; 4 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Mölndal, Sweden., Guié MA; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Habeshian S; 3 X-Chem Pharmaceuticals, Waltham, MA, USA.; 8 École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Keefe AD; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Schlenker O; 2 Heptares Therapeutics Ltd., Welwyn Garden City, Hertfordshire, UK., Sigel EA; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Snijder A; 4 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Mölndal, Sweden., Soutter HT; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Sundström L; 4 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Mölndal, Sweden., Troast DM; 3 X-Chem Pharmaceuticals, Waltham, MA, USA.; 9 Morphic Therapeutic, Waltham, MA., Wiggin G; 2 Heptares Therapeutics Ltd., Welwyn Garden City, Hertfordshire, UK., Zhang J; 1 Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Waltham, MA, USA.; 10 Entasis Therapeutics, Waltham, MA., Zhang Y; 3 X-Chem Pharmaceuticals, Waltham, MA, USA., Clark MA; 3 X-Chem Pharmaceuticals, Waltham, MA, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2018 Jun; Vol. 23 (5), pp. 429-436. Date of Electronic Publication: 2018 Jan 09.
Autor:
Fernández-Montalván AE; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Berger M; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Kuropka B; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Koo SJ; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Badock V; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Weiske J; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Puetter V; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Holton SJ; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Stöckigt D; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Ter Laak A; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Centrella PA; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Clark MA; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Dumelin CE; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Sigel EA; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Soutter HH; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Troast DM; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Zhang Y; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Cuozzo JW; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Keefe AD; X-Chem Pharmaceuticals , Waltham, Massachusetts United States., Roche D; Edelris , Lyon, France., Rodeschini V; Edelris , Lyon, France., Chaikuad A; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom., Díaz-Sáez L; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom., Bennett JM; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom., Fedorov O; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom., Huber KVM; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford , Oxford, United Kingdom., Hübner J; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Weinmann H; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Hartung IV; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany., Gorjánácz M; Bayer AG , Pharmaceuticals, Drug Discovery, Berlin, Germany.
Publikováno v:
ACS chemical biology [ACS Chem Biol] 2017 Nov 17; Vol. 12 (11), pp. 2730-2736. Date of Electronic Publication: 2017 Oct 24.