Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tristen V. Tellman"'
Autor:
Perla C. Reyes Fernandez, Christian S. Wright, Adrianna N. Masterson, Xin Yi, Tristen V. Tellman, Andrei Bonteanu, Katie Rust, Megan L. Noonan, Kenneth E. White, Karl J. Lewis, Uma Sankar, Julia M. Hum, Gregory Bix, Danielle Wu, Alexander G. Robling, Rajesh Sardar, Mary C. Farach-Carson, William R. Thompson
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1857 (2022)
Our understanding of how osteocytes, the principal mechanosensors within bone, sense and perceive force remains unclear. Previous work identified “tethering elements” (TEs) spanning the pericellular space of osteocytes and transmitting mechanical
Externí odkaz:
https://doaj.org/article/a1392b417754406fb1656b6685dd4912
Publikováno v:
Biology, Vol 11, Iss 9, p 1271 (2022)
The bone marrow tumor microenvironment (BMTE) is a complex network of cells, extracellular matrix, and sequestered signaling factors that initially act as a hostile environment for disseminating tumor cells (DTCs) from the cancerous prostate. Three-d
Externí odkaz:
https://doaj.org/article/8f08e99e35e44d2bba9b8c1b76909c0b
Autor:
Brian J. Grindel, Jerahme R. Martinez, Tristen V. Tellman, Daniel A. Harrington, Hamim Zafar, Luay Nakhleh, Leland W. Chung, Mary C. Farach-Carson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Interrupting the interplay between cancer cells and extracellular matrix (ECM) is a strategy to halt tumor progression and stromal invasion. Perlecan/heparan sulfate proteoglycan 2 (HSPG2) is an extracellular proteoglycan that orchestrates t
Externí odkaz:
https://doaj.org/article/8935ec92739f447caf240d440556ed12
Autor:
Dominik Awad, Thomas L. Pulliam, Meredith Spradlin, Pham Hong-Anh Cao, Elavarasan Subramani, Tristen V. Tellman, Caroline F. Ribeiro, Hubert Pakula, Jeffrey J. Ackroyd, Mollianne M. Murray, Jenny J. Han, Badrajee Piyarathna, Justin M. Drake, Michael M. Ittmann, Cristian Coarfa, Mary C. Farach-Carson, Massimo Loda, Livia S. Eberlin, Daniel E. Frigo
SummaryLipid metabolism plays a central role in prostate cancer. To date, the major focus on prostate cancer lipid metabolism has centered onde novolipogenesis and lipid uptake with little consideration for how cancer cells access these lipids once t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e86730db8380faa6251dbcc590f0e44
https://doi.org/10.1101/2022.11.02.514910
https://doi.org/10.1101/2022.11.02.514910
Autor:
Tristen V. Tellman, Merve Dede, Vikram A. Aggarwal, Duncan Salmon, Alexandra Naba, Mary C. Farach-Carson
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 111
The extracellular matrix (ECM) is a highly dynamic, well-organized acellular network of tissue-specific biomolecules, that can be divided into structural or core ECM proteins and ECM-associated proteins. The ECM serves as a blueprint for organ develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34999c6877e04e4f2289d7fbb6888741
https://pubmed.ncbi.nlm.nih.gov/35714875
https://pubmed.ncbi.nlm.nih.gov/35714875
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 3218, p 3218 (2021)
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 3218, p 3218 (2021)
The Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex at the cell surface of prostate cancer (PCa) cells influences cell–cell cohesion and dyscohesion. We investigated matrix metalloproteinase-7/matrilysin (MMP-7)’s ability to digest c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace88ecd2225c69de5063651e916e492
https://pubmed.ncbi.nlm.nih.gov/33809984
https://pubmed.ncbi.nlm.nih.gov/33809984
Flipping the Molecular Switch: Influence of Perlecan and Its Modifiers in the Tumor Microenvironment
Publikováno v:
Advances in experimental medicine and biology. 1245
The tumor microenvironment (TME) is rich in matrix components, growth factors, cytokines, and enzymatic modifiers that respond to changing conditions, to alter the fundamental properties of the tumor bed. Perlecan/HSPG2, a large, multi-domain heparan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9590bb6018aa51cd8b475283507931d6
https://pubmed.ncbi.nlm.nih.gov/32266656
https://pubmed.ncbi.nlm.nih.gov/32266656
Flipping the Molecular Switch: Influence of Perlecan and Its Modifiers in the Tumor Microenvironment
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030401450
The tumor microenvironment (TME) is rich in matrix components, growth factors, cytokines, and enzymatic modifiers that respond to changing conditions, to alter the fundamental properties of the tumor bed. Perlecan/HSPG2, a large, multi-domain heparan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33b9c5b93a26fd2a6feedcca7b936465
https://doi.org/10.1007/978-3-030-40146-7_6
https://doi.org/10.1007/978-3-030-40146-7_6
Autor:
Mary C. Farach-Carson, Tristen V. Tellman, Daniel D. Carson, Oleg A. Igoshin, Lissette A. Cruz
Publikováno v:
Cancer Research. 81:3120-3120
Background: Polarized epithelium is stabilized by lateral cell-cell interactions via cell adhesion molecules (CAMs) and by cell-matrix interactions with basement membrane including with perlecan/HSPG2 (pln). Prostate cancer (PCa) patients with bone m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21daea4e692299d20cf50f975f7450a9
https://doi.org/10.1158/1538-7445.am2021-3120
https://doi.org/10.1158/1538-7445.am2021-3120
Autor:
Mary C. Farach-Carson, Tristen V. Tellman, Lindsey K. Sablatura, Leland W.K. Chung, Brian J. Grindel, Lissette A. Cruz
Publikováno v:
Cancer Research. 80:2650-2650
Introduction: For prostate cancer (PCa), the major site of metastasis is the bone, where disseminated PCa cells can remain dormant for years after colonization. The events that end dormancy and trigger recurrence in the skeletal system, leading to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44eed58d8c08c91f208831ca78ca262
https://doi.org/10.1158/1538-7445.am2020-2650
https://doi.org/10.1158/1538-7445.am2020-2650