Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tristano Pancani"'
Autor:
Tristano Pancani, Michelle Day, Tatiana Tkatch, David L. Wokosin, Patricia González-Rodríguez, Jyothisri Kondapalli, Zhong Xie, Yu Chen, Vahri Beaumont, D. James Surmeier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The corticostriatal dysfunction underlying Huntington’s disease remains incompletely understood. Here, the authors find increased intratelencephalic connectivity resulting from deficient cholinergic transmission in a mouse model of Huntington’s d
Externí odkaz:
https://doaj.org/article/9f3da2a974ae4bf7836154aa87353185
Autor:
Eric M Blalock, Jeremiah T Phelps, Tristano Pancani, James L Searcy, Katie L Anderson, John C Gant, Jelena Popovic, Margarita G Avdiushko, Don A Cohen, Kuey-Chu Chen, Nada M Porter, Olivier Thibault
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10405 (2010)
Thiazolidinediones (TZDs) activate peroxisome proliferator-activated receptor gamma (PPARgamma) and are used clinically to help restore peripheral insulin sensitivity in Type 2 diabetes (T2DM). Interestingly, long-term treatment of mouse models of Al
Externí odkaz:
https://doaj.org/article/a5c9cec00f114fa6a8cdca7e9c312083
Autor:
Dalton Surmeier, Tristano Pancani, Michelle Day, Tatiana Tkatch, David Wokosin, Patricia Gonzalez Rodriguez, Jyothisri Kondapalli, Yu Chen, Vahri Beaumont
Huntington’s disease (HD) is a progressive, neurodegenerative disease caused by a CAG triplet expansion in the huntingtin gene. Although corticostriatal dysfunction has long been implicated in HD, the determinants and pathway specificity of this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4164bfd87532202802cf694e21287008
https://doi.org/10.21203/rs.3.rs-1008365/v1
https://doi.org/10.21203/rs.3.rs-1008365/v1
Autor:
Sean Austin O. Lim, Asami Tanimura, Tristano Pancani, Weixing Shen, Cecilia Tubert, Dalton James Surmeier, Alexandra E. Melendez
Publikováno v:
European Journal of Neuroscience. 47:1148-1158
Giant, aspiny cholinergic interneurons (ChIs) have long been known to be key nodes in the striatal circuitry controlling goal-directed actions and habits. In recent years, new experimental approaches, like optogenetics and monosynaptic rabies virus m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53a4fc7fd276f4d5f9e88531bc9575a
https://doi.org/10.1111/ejn.13638
https://doi.org/10.1111/ejn.13638
Autor:
Tristano Pancani, Zixiu Xiang, P. Jeffrey Conn, Caroline Bolarinwa, Yoland Smith, Craig W. Lindsley
Publikováno v:
ACS Chemical Neuroscience. 5:318-324
The striatum is the main input station of the basal ganglia and is extensively involved in the modulation of motivated behavior. The information conveyed to this subcortical structure through glutamatergic projections from the cerebral cortex and tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8cc14ecfdb92d5c7c2f8ff5a1fecc4
https://doi.org/10.1021/cn500003z
https://doi.org/10.1021/cn500003z
Autor:
Tristano Pancani, Inga Kadish, Kuey-Chu Chen, Nada M. Porter, Jelena Popovic, Eric M. Blalock, James L. Searcy, Michael Paul Murphy, Katie L. Anderson, Philip W. Landfield, Olivier Thibault, Tina L. Beckett, Jeremiah T. Phelps
Publikováno v:
Journal of Alzheimer's Disease. 30:943-961
Thiazolidinediones (TZDs) are agonists at peroxisome proliferator-activated gamma-type (PPAR-γ) receptors and are used clinically for the treatment of type 2 diabetes where they have been shown to reestablish insulin sensitivity, improve lipid profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d368576f8447819fa800fbb13a5ed879
https://doi.org/10.3233/jad-2012-111661
https://doi.org/10.3233/jad-2012-111661
Autor:
Zixiu Xiang, Tristano Pancani, Nellie Byun, Jerri M. Rook, Mark S. Moehle, Colleen M. Niswender, Johnathan W. Dickerson, Daniel H. Remke, Craig W. Lindsley, Jürgen Wess, Carrie K. Jones, P. Jeffrey Conn, Samantha E. Yohn, George H. Wilson
Publikováno v:
Neuron. 96:1358-1372.e4
Summary Cholinergic regulation of dopaminergic inputs into the striatum is critical for normal basal ganglia (BG) function. This regulation of BG function is thought to be primarily mediated by acetylcholine released from cholinergic interneurons (Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b560821e823e845b02fc5f58c28736
https://doi.org/10.1016/j.neuron.2017.12.008
https://doi.org/10.1016/j.neuron.2017.12.008
Autor:
Jeremiah T. Phelps, Kuey-Chu Chen, Nada M. Porter, Michael W. Kilgore, James L. Searcy, Olivier Thibault, Tristano Pancani
Publikováno v:
Journal of Neurochemistry. 109:1800-1811
Type 2 diabetes mellitus is a metabolic disorder characterized by hyperglycemia and is especially prevalent in the elderly. Because aging is a risk factor for type 2 diabetes mellitus, and insulin resistance may contribute to the pathogenesis of Alzh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbace1761fe652dabec4a838fd30a05
https://doi.org/10.1111/j.1471-4159.2009.06107.x
https://doi.org/10.1111/j.1471-4159.2009.06107.x
Autor:
Tristano Pancani, Carrie K. Jones, Jerri M. Rook, Michael R. Wood, Zixiu Xiang, Colleen M. Niswender, Aaron B. Bowman, Mark S. Moehle, Daniel J. Foster, Emma M. Bradley, Terry Jo Bichell, Craig W. Lindsley, Thomas M. Bridges, Mike Poslusney, P. Jeffrey Conn, Rebecca Klar, J. Scott Daniels
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(45)
Significance Huntington’s disease (HD) is a devastating neurodegenerative genetic disorder characterized by progressive decline of motor control. Although the genetic mutation responsible for the syndrome associated with HD has been clearly identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5c92eb2a41e345d422c45ff6092c11
https://pubmed.ncbi.nlm.nih.gov/26508634
https://pubmed.ncbi.nlm.nih.gov/26508634
Autor:
Luna Venturi, Elena Gramigni, Andrea Cozzi, Domenico E. Pellegrini-Giampietro, Alberto Chiarugi, Raffaele De Gaudio, Alessia Tani, Chiara Adembri, Tristano Pancani
Publikováno v:
Anesthesiology. 104:80-89
Background Propofol (2,6-diisopropylphenol) has been shown to attenuate neuronal injury in a number of experimental conditions, but studies in models of cerebral ischemia have yielded conflicting results. Moreover, the mechanisms involved in its neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e1ded0215043e3bade21b9f46661a3
https://doi.org/10.1097/00000542-200601000-00014
https://doi.org/10.1097/00000542-200601000-00014