Development of a digital platform to improve community response to overdose and prevention among harm reduction organizations

Autor: Kasey Claborn, Suzannah Creech, Fiona N. Conway, Nina M. Clinton, Katlyn T. Brinkley, Elizabeth Lippard, Tristan Ramos, Jake Samora, Aaron Miri, Justin Benzer

Publikováno v: Harm Reduction Journal, Vol 19, Iss 1, Pp 1-11 (2022)

Abstract The overdose crisis in the USA remains a growing and urgent public health concern. Over 108,000 people died due to overdose during 2021. Fatal and non-fatal overdoses are under-reported in the USA due to current surveillance methods. Systemi

Externí odkaz: https://doaj.org/article/eb8b48207902445fb26bbc15d22260ec

sRNA/L1 retrotransposition : using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay

Autor: Tristan-Ramos, Pablo, Morell, Santiago, Sanchez, Laura, Toledo, Belen, Garcia-Perez, Jose L., Heras, Sara R.

Publikováno v: Philosophical Transactions: Biological Sciences, 2020 Mar . 375(1795), 1-12.

Externí odkaz: https://www.jstor.org/stable/27014537

The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

Autor: Suyapa Amador-Cubero, Sebastien Viollet, Laura Sánchez, Alejandro Rubio-Roldan, Pablo Tristan-Ramos, Sara R. Heras, Gaël Cristofari, Guillermo Peris

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5712. ⟨10.1038/s41467-020-19430-4⟩
Repositori Universitat Jaume I
Universitat Jaume I
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5712. ⟨10.1038/s41467-020-19430-4⟩
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname

Nearly half of the human genome is made of transposable elements (TEs) whose activity continues to impact its structure and function. Among them, Long INterspersed Element class 1 (LINE-1 or L1) elements are the only autonomously active TEs in humans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a799ef5b76da6b6658f2cff13a6154
https://doaj.org/article/92f12109ce524c348a62859af39c4dc9

Supplementary Material from sRNA/L1-retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay

Autor: Tristan-Ramos, Pablo, Morell, Santiago, Sanchez, Laura, Belen Toledo, Garcia-Perez, Jose L., Heras, Sara R.

The file contains two Tables and three Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e410b46d927784e3e474c784445300

Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons

Autor: Valentin Sanchez-Carnerero, Carmen Salvador-Palomeque, Juan A. Tamayo, Pablo Tristan-Ramos, Laura Sánchez, Guillermo Banuelos-Sanchez, Jose L. Garcia-Perez, Maria Benitez-Guijarro, Santiago Morell, Jose L. Garcia-Puche, Francisco Franco-Montalban, Sara R. Heras, Meriem Benkaddour-Boumzaouad

Publikováno v: Cell Chemical Biology. 26:1095-1109.e14

Retrotransposons are a type of transposable element (TE) that have amplified to astonishing numbers in mammalian genomes, comprising more than a third of the human and mouse genomes. Long interspersed element class 1 (LINE-1 or L1) retrotransposons a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa94304568032681ea3ddcab670aad
https://doi.org/10.1016/j.chembiol.2019.04.010