Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tristan P. Wallis"'
Autor:
Anmin Jiang, Kye Kudo, Rachel S. Gormal, Sevannah Ellis, Sikao Guo, Tristan P. Wallis, Shanley F. Longfield, Phillip J. Robinson, Margaret E. Johnson, Merja Joensuu, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Endocytosis requires a coordinated framework of molecular interactions that ultimately lead to the fission of nascent endocytic structures. How cytosolic proteins such as dynamin concentrate at discrete sites that are sparsely distributed ac
Externí odkaz:
https://doaj.org/article/417850cc6c004c93857d76a6f63cbd31
Autor:
Belal Shohayeb, Kai Sempert, Tristan P. Wallis, Frédéric A. Meunier, Nela Durisic, Elizabeth A. O'Brien, Cecilia Flores, Helen M. Cooper
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110621- (2024)
Summary: Synaptic structural plasticity, the expansion of dendritic spines in response to synaptic stimulation, is essential for experience-dependent plasticity and is driven by branched actin polymerization. The WAVE regulatory complex (WRC) is conf
Externí odkaz:
https://doaj.org/article/a704eb31b95c4426b58aa8f4f74e4da0
Autor:
Shanley F. Longfield, Rachel S. Gormal, Matis Feller, Pierre Parutto, Jürgen Reingruber, Tristan P. Wallis, Merja Joensuu, George J. Augustine, Ramón Martínez-Mármol, David Holcman, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Neurotransmitter release relies on the regulated fusion of synaptic vesicles (SVs) that are tightly packed within the presynaptic bouton of neurons. The mechanism by which SVs are clustered at the presynapse, while preserving their ability t
Externí odkaz:
https://doaj.org/article/340ae843e8934ea2a097d76a195d9de7
Autor:
Shanley F. Longfield, Mahdie Mollazade, Tristan P. Wallis, Rachel S. Gormal, Merja Joensuu, Jesse R. Wark, Ashley J. van Waardenberg, Christopher Small, Mark E. Graham, Frédéric A. Meunier, Ramón Martínez-Mármol
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Neuronal communication relies on the release of neurotransmitters from various populations of synaptic vesicles. Despite displaying vastly different release probabilities and mobilities, the reserve and recycling pool of vesicles co-exist wi
Externí odkaz:
https://doaj.org/article/dbd5f05e852046bd8c652292e771cdb7
Autor:
Tristan P. Wallis, Anmin Jiang, Kyle Young, Huiyi Hou, Kye Kudo, Alex J. McCann, Nela Durisic, Merja Joensuu, Dietmar Oelz, Hien Nguyen, Rachel S. Gormal, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Single-molecule localization microscopy techniques are emerging as vital tools to unravel the nanoscale world of living cells by understanding the spatiotemporal organization of protein clusters at the nanometer scale. Current analyses defin
Externí odkaz:
https://doaj.org/article/f36f1f2833e14480b10a8a1fee2c2af3
Autor:
Yash Chhabra, Pernille Seiffert, Rachel S. Gormal, Manon Vullings, Christine Mei Mei Lee, Tristan P. Wallis, Farhad Dehkhoda, Sowmya Indrakumar, Nina L. Jacobsen, Kresten Lindorff-Larsen, Nela Durisic, Michael J. Waters, Frédéric A. Meunier, Birthe B. Kragelund, Andrew J. Brooks
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112490- (2023)
Summary: Growth hormone (GH) acts via JAK2 and LYN to regulate growth, metabolism, and neural function. However, the relationship between these tyrosine kinases remains enigmatic. Through an interdisciplinary approach combining cell biology, structur
Externí odkaz:
https://doaj.org/article/f0578a76c2ca4997a9b58592d72fb7fd
Autor:
Tristan P. Wallis, Anmin Jiang, Kyle Young, Huiyi Hou, Kye Kudo, Alex J. McCann, Nela Durisic, Merja Joensuu, Dietmar Oelz, Hien Nguyen, Rachel S. Gormal, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2638d17156644140a64163e6ffb4a2a5
Autor:
Tristan P. Wallis, Bharat G. Venkatesh, Vinod K. Narayana, David Kvaskoff, Alan Ho, Robert K. Sullivan, François Windels, Pankaj Sah, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Changes in poly-unsaturated free fatty acids (FFAs) have been associated with LTP. Here, using lipidomics analysis the authors characterise FFA changes in the rat brain associated with fear conditioning, and demonstrate that increases in saturated FF
Externí odkaz:
https://doaj.org/article/d002f587a77a4023996e7828b8202d54
Autor:
Thu H.M. Nguyen, Patricia E. Carreira, Francisco J. Sanchez-Luque, Stephanie N. Schauer, Allister C. Fagg, Sandra R. Richardson, Claire M. Davies, J. Samuel Jesuadian, Marie-Jeanne H.C. Kempen, Robin-Lee Troskie, Cini James, Elizabeth A. Beaven, Tristan P. Wallis, Jermaine I.G. Coward, Naven P. Chetty, Alexander J. Crandon, Deon J. Venter, Jane E. Armes, Lewis C. Perrin, John D. Hooper, Adam D. Ewing, Kyle R. Upton, Geoffrey J. Faulkner
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3730-3740 (2018)
Summary: LINE-1 (L1) retrotransposons are a source of insertional mutagenesis in tumor cells. However, the clinical significance of L1 mobilization during tumorigenesis remains unclear. Here, we applied retrotransposon capture sequencing (RC-seq) to
Externí odkaz:
https://doaj.org/article/02b2c6ba831b4bec8988f6149861dbe1
Autor:
Ramón Martínez-Mármol, Christopher Small, Anmin Jiang, Tishila Palliyaguru, Tristan P. Wallis, Rachel S. Gormal, Jean-Baptiste Sibarita, Jürgen Götz, Frédéric A. Meunier
Publikováno v:
Molecular Psychiatry. 28:946-962
Fyn is a Src kinase that controls critical signalling cascades and has been implicated in learning and memory. Postsynaptic enrichment of Fyn underpins synaptotoxicity in dementias such as Alzheimer’s disease and frontotemporal lobar degeneration w