Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tristan J Hayeck"'
Autor:
Chin Hur, Tristan J Hayeck, Jennifer M Yeh, Ethan M Richards, Stuart J Spechler, G Scott Gazelle, Chung Yin Kong
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9483 (2010)
The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. The aim of the study was to begin the investigation of this rapid rise by developing, calibrating, and validating a mathematical disease simulation mode
Externí odkaz:
https://doaj.org/article/dbc807415c6f4988ad9d7c79fed55bd6
Autor:
David J. Margolis, Jamie L. Duke, Nandita Mitra, Ronald A. Berna, Ole J. Hoffstad, Jenna R. Wasserman, Amalia Dinou, Georgios Damianos, Ioanna Kotsopoulou, Nikolaos Tairis, Deborah A. Ferriola, Timothy L. Mosbruger, Tristan J. Hayeck, Albert C. Yan, Dimitri S. Monos
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Components of the immune response have previously been associated with the pathophysiology of atopic dermatitis (AD), specifically the Human Leukocyte Antigen (HLA) Class II region via genome-wide association studies, however the exact
Externí odkaz:
https://doaj.org/article/daca908e2e89473c9add552149a5579e
Autor:
Evin M. Padhi, Tristan J. Hayeck, Zhang Cheng, Sumantra Chatterjee, Brandon J. Mannion, Marta Byrska-Bishop, Marjolaine Willems, Lucile Pinson, Sylvia Redon, Caroline Benech, Kevin Uguen, Séverine Audebert-Bellanger, Cédric Le Marechal, Claude Férec, Stephanie Efthymiou, Fatima Rahman, Shazia Maqbool, Reza Maroofian, Henry Houlden, Rajeeva Musunuri, Giuseppe Narzisi, Avinash Abhyankar, Riana D. Hunter, Jennifer Akiyama, Lauren E. Fries, Jeffrey K. Ng, Elvisa Mehinovic, Nick Stong, Andrew S. Allen, Diane E. Dickel, Raphael A. Bernier, David U. Gorkin, Len A. Pennacchio, Michael C. Zody, Tychele N. Turner
Publikováno v:
Human Genomics, Vol 15, Iss 1, Pp 1-15 (2021)
Abstract Background Previous research in autism and other neurodevelopmental disorders (NDDs) has indicated an important contribution of protein-coding (coding) de novo variants (DNVs) within specific genes. The role of de novo noncoding variation ha
Externí odkaz:
https://doaj.org/article/a0957b4159c64ec8b85c8227ab117a02
Autor:
Tristan J Hayeck, George B Busby, Sung Chun, Anna C F Lewis, Megan C Roberts, Bjarni J Vilhjálmsson
Publikováno v:
Hayeck, T J, Busby, G B, Chun, S, Lewis, A C F, Roberts, M C & Vilhjálmsson, B J 2023, ' Polygenic Risk Scores : Genomes to Risk Prediction ', Clinical Chemistry . https://doi.org/10.1093/clinchem/hvad049
Autor:
Tristan J Hayeck, Nicholas Stong, Evan Baugh, Ryan Dhindsa, Tychele N Turner, Ayan Malakar, Timothy L Mosbruger, Grace Tzun-Wen Shaw, Yuncheng Duan, Iuliana Ionita-Laza, David Goldstein, Andrew S Allen
Publikováno v:
Genetics
Genomic regions subject to purifying selection are more likely to carry disease-causing mutations than regions not under selection. Cross species conservation is often used to identify such regions but with limited resolution to detect selection on s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164dbc60536265bce33451a5269af281
https://europepmc.org/articles/PMC9157129/
https://europepmc.org/articles/PMC9157129/
Autor:
Adam Gleason, Mahdi Sarmady, Timothy Mosbruger, Laura K. Conlin, Georgios Damianos, Dimitrios Monos, Tristan J. Hayeck, Jonathan P. Bradfield, Jamie L. Duke, Tychele N. Turner
Balancing selection occurs when different evolutionary pressures impact the fitness of multiple alleles, resulting in increased allelic diversity in the population. A new statistical method was developed to test for selection, improving inference by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d68517d9e36dc1d363e95630fca05a64
https://doi.org/10.1101/2021.09.28.462165
https://doi.org/10.1101/2021.09.28.462165
Autor:
Jamie L. Duke, Taishan Hu, Mengkai Shieh, Carolina Kneib, Deborah Ferriola, Ryan Morlen, Nilesh Chitnis, Dimitri S. Monos, Timothy Mosbruger, Anh Dinh, Tristan J. Hayeck, Yanping Huang
Publikováno v:
Transplantation
Background HLA molecular mismatch (MM) is a risk factor for de novo donor-specific antibody (dnDSA) development in solid organ transplantation. HLA expression differences have also been associated with adverse outcomes in hematopoietic cell transplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b427916e6891c7cf9ed968cb3848fd1
https://europepmc.org/articles/PMC8628253/
https://europepmc.org/articles/PMC8628253/
Autor:
Rajeeva Musunuri, Evin M Padhi, Tristan J. Hayeck, Diane E. Dickel, Sumantra Chatterjee, Brandon J. Mannion, Jennifer A. Akiyama, Avinash Abhyankar, Tychele N. Turner, Zhang Cheng, David U. Gorkin, Michael C. Zody, Len A. Pennacchio, Nick Stong, Jeffrey K. Ng, Giuseppe Narzisi, Lauren E. Fries, Raphael Bernier, Marta Byrska-Bishop, Riana D. Hunter, Andrew S. Allen
Author(s): Padhi, Evin M; Hayeck, Tristan J; Mannion, Brandon; Chatterjee, Sumantra; Byrska-Bishop, Marta; Musunuri, Rajeeva; Narzisi, Giuseppe; Abhyankar, Avinash; Cheng, Zhang; Hunter, Riana D; Akiyama, Jennifer; Fries, Lauren E; Ng, Jeffrey; Stong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ce5e385530c322e8a97f3800633d4b5
https://doi.org/10.1101/2020.08.28.270751
https://doi.org/10.1101/2020.08.28.270751
Autor:
Tristan J. Hayeck, Nicholas Stong, Evan Baugh, Ryan Dhindsa, Tychele N. Turner, Ayan Malakar, Timothy L. Mosbruger, Yuncheng Duan, Iuliana Ionita-Laza, David Goldstein, Andrew S. Allen
Genomic regions subject to purifying selection are of greater importance to the health and survival of an organism than regions not under such selection and therefore more likely to carry disease causing mutations in humans. Methods for identifying s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a608294a4dcd500c70e3b4a94715eb
Autor:
Tristan J. Hayeck, Yanping Huang, Dimitri S. Monos, Taishan Hu, Jamie L. Duke, Ryan Morlen, Timothy Mosbruger, Deborah Ferriola, Carolina Kneib, Anh Dinh, Nilesh Chitnis, Mengkai Shieh
BackgroundHLA molecular mismatch (MM) has been shown to be a risk factor for de novo donor-specific antibody (dnDSA) development in solid organ transplantation (SOT). HLA expression differences have also been associated with adverse outcomes in hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9415a714e2dd6757bb29d81ba7377e1
https://doi.org/10.1101/2020.01.06.20016709
https://doi.org/10.1101/2020.01.06.20016709