Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomised, double-blind, placebo-controlled, phase 3 trial

Autor: Abdellatif Tazi, Aurélie Le Borgne-Krams, Marine Cachanado, Tabassome Simon, Sylvain Marchand-Adam, Morgane Didier, Lidwine Wemeau-Stervinou, Sandrine Hirschi, Frédéric Rivière, Arnaud Bourdin, François Lebargy, Stéphane Dominique, Aude Gibelin, Alexandre Chabrol, Tristan Dégot, Jacques Cadranel, Martine Reynaud-Gaubert, Marie-Pierre Debray, Sylvie Leroy, Frédéric Gagnadoux, Emmanuel Bergot, François-Xavier Blanc, Alexandra Rousseau, Raphael Borie, Pierre Yves Brillet, Guillaume Beltramo, Mallorie Kerjouan, Hilario Nunes, Olivia Freynet, Julie Traclet, Bruno Crestani, Anne-Sophie Gamez, Grégoire Prévot, Jean Pastré, Dominique Israel-Biet, Marie-Christine Dombret, Laurent Plantier, Cécile Chenivesse, Laurence Berard, Ana Nieves, Emmanuel Gomez, Dominique Valeyre, Stéphane Jouneau, Anne Gondouin, Elodie Blanchard, C. Launois, Nathalie Bautin, Jean-Marc Naccache, Vincent Cottin, Antoine Parrot, Philippe Bonniaud

Publikováno v: The Lancet Respiratory Medicine
The Lancet Respiratory Medicine, 2022, 10 (1), pp.26-34. ⟨10.1016/S2213-2600(21)00354-4⟩
The Lancet Respiratory Medicine, Elsevier, 2021, ⟨10.1016/S2213-2600(21)00354-4⟩

Summary Background The use of cyclophosphamide in patients with acute exacerbation of idiopathic pulmonary fibrosis (IPF) is unknown. Our study was designed to evaluate the efficacy and safety of four cyclophosphamide pulses in addition to high-dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691aabc7559d1112b47b6efd1428d864
https://doi.org/10.1016/s2213-2600(21)00354-4

RCT Abstract - Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomized, double-blind, placebo-controlled, phase 3 trial

Autor: Jean-Marc Naccache, Morgane Didier, Hilario Nunes, Julie Traclet, Olivia Freynet, Dominique Israel-Biet, Alexandre Chabrol, Arnaud Bourdin, Nathalie Bautin, Emmanuel Bergot, Grégoire Prévot, Jean Pastré, Sylvie Leroy, Philippe Bonniaud, Tristan Dégot, Frédéric Rivière, Raphael Borie, Cécile Chenivesse, Vincent Cottin, Lidwine Wemeau-Stervinou, Bruno Crestani, Martine Reynaud-Gaubert, Antoine Parrot, Dominique Valeyre, Marie-Christine Dombret, Malorie Kerjouan, Abdellatif Tazi, Anne Gondouin, Stéphane Jouneau, Elodie Blanchard, Sylvain Marchand-Adam, Sandrine Hirschi, C. Launois, Ana Nieves, Stéphane Dominique, François-Xavier Blanc, Jacques Cadranel, Marie-Pierre Debray, Anne-Sophie Gamez, Frédéric Gagnadoux, Marine Cachanado, Laurence Berard, Guillaume Beltramo, Tabassome Simon, Pierre-Yves Brillet, A. Gibelin, Emmanuel Gomez, Aurélie Le Borgne-Krams, François Lebargy, Alexandra Rousseau, Laurent Plantier

Publikováno v: Idiopathic interstitial pneumonias.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::520abdb01df82cbb27c7a0375c70154a
https://doi.org/10.1183/13993003.congress-2021.rct2903

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Clinical characteristics of and outcomes for patients with COVID-19 and comorbid lung diseases primarily hospitalized in a conventional pulmonology unit: A retrospective study

Autor: Carole Ederle, Sandrine Hirschi, Eva Chatron, Michele Porzio, Loic Kassegne, Benjamin Renaud-Picard, C. Marcot, Ronald C. Kessler, Tristan Dégot, Pierre Leyendecker, Aissam Labani, Carine Metz-Favre, F. De Blay, Matthieu Canuet, N. Khayath, Marianne Riou

Publikováno v: Respiratory Medicine and Research
Respiratory Medicine and Research, Elsevier, 2021, 79, pp.100801-. ⟨10.1016/j.resmer.2020.100801⟩
Respiratory Medicine and Research, 2021, 79, pp.100801-. ⟨10.1016/j.resmer.2020.100801⟩

International audience; Background: Scant data are currently available about a potential link between comorbid chronic lung diseases (CLD) and the risk and severity of the coronavirus disease 2019 (COVID-19) infection.Methods: To describe the clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ecefa09c50f0efe47f9b8b175d7468
https://hal.archives-ouvertes.fr/hal-03493176

The social and clinical impact of the COVID‐19 epidemic on the Strasbourg lung transplant cohort: A single‐center retrospective cohort study

Autor: Floriane Gallais, A. Schuller, Sophie Freudenberger, Tristan Dégot, Eva Chatron, Sandrine Hirschi, Michele Porzio, Marianne Riou, Romain Kessler, Julien Stauder, Benjamin Renaud-Picard

Publikováno v: Clinical Transplantation

The clinical and social impacts of the COVID‐19 epidemic on lung transplant (LTx) recipients remain poorly known. We aimed to evaluate its social, clinical, and behavioral consequences on the LTx patients followed in Strasbourg university hospital.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3f456b98b8cf54de767010d2618fbc
http://europepmc.org/articles/PMC7646014