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Autor:
James A. Thomas, Tripti Bishwas, Rachna Chandra, Zoltán Németh, Zoltán Spolarics, Stephanie Federici, Edwin A. Deitch
Publikováno v:
Inflammation. 36:1503-1512
Interleukin-1 receptor-associated kinase (IRAK1) is a key regulatory protein in TLR/IL1R-mediated cell activation during inflammatory response. Studies indicated that pending on the nature of the used inflammatory model, downregulation of IRAK1 may b