Zobrazeno 1 - 10
of 1 988
pro vyhledávání: '"Triple-Negative Breast Cancer TNBC"'
Autor:
Kasshish Mehta, Mangala Hegde, Sosmitha Girisa, Ravichandran Vishwa, Mohammed S. Alqahtani, Mohamed Abbas, Mehdi Shakibaei, Gautam Sethi, Ajaikumar B. Kunnumakkara
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-25 (2024)
Abstract The extensive heterogeneity and the limited availability of effective targeted therapies contribute to the challenging prognosis and restricted survival observed in triple-negative breast cancer (TNBC). Recent research indicates the aberrant
Externí odkaz:
https://doaj.org/article/115a9fb9250e40cba2910b5b0fb8a51c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cancer stem cells (CSCs) have the potential to self-renew and induce cancer, which may contribute to a poor prognosis by enabling metastasis, recurrence, and therapy resistance. Hence, this study was performed to identify the association bet
Externí odkaz:
https://doaj.org/article/8824695dcd1b4090affa6514bc9533fb
Autor:
Xiaorong Hou, Zhaofang Bai, Yuanyuan Chen, Wei Shi, Huijie Yang, Ruisheng Li, Xiaoyan Zhan, Youping Liu, Xu Zhao, Xiaohe Xiao
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Squama Manis is a valuable traditional Chinese medicine with a long history of medicinal use in the treatment of breast-related diseases. However, owing to the excessive exploitation and utilization of the resources, Squama Manis
Externí odkaz:
https://doaj.org/article/d44439efc9634ef1bbd8ed34823afca3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Caspase-9, a cysteine-aspartate protease traditionally associated with intrinsic apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell migration—an aspect that has received limited attention in existing
Externí odkaz:
https://doaj.org/article/d6c38addebef427a837cb03ba929581a
Autor:
Gowthami Mahendran, Ann Dharshika Shangaradas, Ricardo Romero-Moreno, Nadeeshika Wickramarachchige Dona, S. H. G. Sumudu Sarasija, Sumeth Perera, Gayathri N. Silva
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Triple-negative breast cancer (TNBC) is a highly aggressive and clinically challenging subtype of breast cancer, lacking the expression of estrogen receptor (ER), progesterone receptor (PR), and HER2/neu. The absence of these receptors limits therape
Externí odkaz:
https://doaj.org/article/1e50514d378b4bcc823e96ee5f44f297
Publikováno v:
Cancer Medicine, Vol 13, Iss 20, Pp n/a-n/a (2024)
ABSTRACT Background Emerging evidence has indicated possible efficacy benefit of platinum‐based chemotherapy as neoadjuvant treatment for invasive ductal carcinoma triple‐negative breast cancer (TNBC). However, it has not been endorsed by current
Externí odkaz:
https://doaj.org/article/6d0f6ca7fb3b4be1823b4100e98a315d
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Backgrounds Microfibril-associated protein 2 (MFAP2) is a protein presenting in the extracellular matrix that governs the activity of microfibrils through its interaction with fibrillin. While the involvement of MFAP2 in metabolic disorders
Externí odkaz:
https://doaj.org/article/9b1873c6a0364e79848fd23a686e88b8
Autor:
Zhenzhen Jiang, Guangqing Cai, Haiting Liu, Leping Liu, Rong Huang, Xinmin Nie, Rong Gui, Jian Li, Jinqi Ma, Ke Cao, Yanwei Luo
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Combination therapy involving immune checkpoint blockade (ICB) and other drugs is a potential strategy for converting immune-cold tumors into immune-hot tumors to benefit from immunotherapy. To achieve drug synergy, we developed a
Externí odkaz:
https://doaj.org/article/a85048a859814ff5baf461bad2ecc150
Autor:
Francesca Cirillo, Asia Spinelli, Marianna Talia, Domenica Scordamaglia, Maria Francesca Santolla, Fedora Grande, Bruno Rizzuti, Marcello Maggiolini, Céline Gérard, Rosamaria Lappano
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Estetrol (E4) is a natural estrogen produced by the fetal liver during pregnancy. Due to its favorable safety profile, E4 was recently approved as estrogenic component of a new combined oral contraceptive. E4 is a selective ligand
Externí odkaz:
https://doaj.org/article/095d6167bd79405e95e77b5a69c80c94
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36935- (2024)
Breast cancer emerges as one of the most prevalent malignancies in women, its incidence showing a concerning upward trend. Among the diverse array of breast cancer subtypes, triple-negative breast cancer (TNBC) assumes notable significance, due to la
Externí odkaz:
https://doaj.org/article/6afae0fbe85d4a9f8c05f8145575e1f9