Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Trini Arroyo"'
Autor:
Yuanhao Li, Neeraja Idamakanti, Trini Arroyo, Steve Thorne, Tony Reid, Scott Nichols, Melinda VanRoey, Gail Colbern, Natalie Nguyen, Orlena Tam, Peter Working, De-Chao Yu
Publikováno v:
Clinical Cancer Research. 11:8845-8855
Purpose: Transcriptionally controlled oncolytic adenovirus CG5757 is engineered with two tumor-specific promoters from E2F-1 and human telomerase reverse transcriptase genes. This virus has broad anticancer spectrum and higher specificity. The object
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90c8c88630a179741a5e0e8085ffe30
https://doi.org/10.1158/1078-0432.ccr-05-1757
https://doi.org/10.1158/1078-0432.ccr-05-1757
Autor:
Yuanhao, Li, Yu, Chen, Jeanette, Dilley, Trini, Arroyo, Derek, Ko, Peter, Working, De-Chao, Yu
Publikováno v:
Molecular cancer therapeutics. 2(10)
Human carcinoembryonic antigen (CEA) is overexpressed in most colorectal cancers and has been widely used as a clinical marker for the management of colon cancer patients. The transcriptional regulatory elements (TREs) of CEA include two enhancer ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78c3bfb560b2aa84cdaf4c6ee54d5cfa
https://pubmed.ncbi.nlm.nih.gov/14578465
https://pubmed.ncbi.nlm.nih.gov/14578465
Autor:
Melinda VanRoey, Gail Colben, P. Seshidhar Reddy, De-Chao Yu, Derek Ko, Orlena Tam, Natalie Nguyen, Neeraja Idamakanti, Trini Arroyo, Yuanhao Li
Publikováno v:
Molecular Therapy. 9:S169-S170
Replication-selective oncolytic viruses hold promise for the treatment of cancer. Among this novel group of therapeutics are oncolytic adenoviruses engineered with tumor-specific transcriptional response elements (TRE) controlling essential genes. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529f040f3615b919027b7892a48a40f5
https://doi.org/10.1016/j.ymthe.2004.06.375
https://doi.org/10.1016/j.ymthe.2004.06.375
Autor:
Natalie Nguyen, Neeraja Idamakanti, Tony R. Reid, Melinda VanRoey, Trini Arroyo, Gail Colbern, De-Chao Yu, Stephen H. Thorne, Yuanhao Li
Publikováno v:
Molecular Therapy. 11:S121
Top of pageAbstract A human adenovirus serotype 5 based oncolytic virus CG5757 was designed to preferentially replicate in and kill cancer cells that have a defective retinoblastoma (Rb) pathway and overexpress telomerase. Tumor selectivity of CG5757
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb478031221ee83faa73f84d90fe7b43
https://doi.org/10.1016/j.ymthe.2005.06.314
https://doi.org/10.1016/j.ymthe.2005.06.314