Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Trinh T. B. Tran"'
Publikováno v:
Applied Microbiology and Biotechnology. 100:9239-9253
Baculoviruses are recognized as viral workhorses of biotechnology, being used for production of vaccines, complex recombinant proteins, gene delivery vectors' and safe biological pesticides. Improving production yields and understanding the interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b68fae7731c1bae22e1b69039a973c5
https://doi.org/10.1007/s00253-016-7774-3
https://doi.org/10.1007/s00253-016-7774-3
Publikováno v:
Applied Microbiology and Biotechnology. 97:5245-5257
The cell density effect is a well-established constraint in the baculovirus-insect cell expression platform, in which cell-specific productivity declines with increasing cell density, hence limiting the maximum achievable volumetric yield of protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6cd62bbfc1fe2299f2db4038a13599
https://doi.org/10.1007/s00253-013-4835-8
https://doi.org/10.1007/s00253-013-4835-8
Autor:
Steven Reid, Trinh T. B. Tran, Hoai T. Huynh, Leslie C. L. Chan, Lars K. Nielsen, Stefanie Dietmair
Publikováno v:
Methods. 56:396-407
Metabolomics refer to the global analysis of small molecule metabolites in a biological system, and can be a powerful tool to elucidate and optimize cellular processes, particularly when integrated into a systems biology framework. Determining the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa9f36600b16ad58ca9bd7363373f1c
https://doi.org/10.1016/j.ymeth.2011.11.009
https://doi.org/10.1016/j.ymeth.2011.11.009
Publikováno v:
Archives of virology. 160(9)
The phenomenon of the reduction in the cell-specific yield with increasing infection cell density (ICD), the cell density effect, is one of the main hurdles for improving virus yields in vitro. In the current study, the reduction in cell-specific yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f226344249a311924d231ef7670311d
https://pubmed.ncbi.nlm.nih.gov/26092423
https://pubmed.ncbi.nlm.nih.gov/26092423
Publikováno v:
Applied microbiology and biotechnology. 99(4)
The phenomenon of the cell density effect is not readily explained by an obvious nutrient limitation, and a recent study has suggested that for recombinant Autographa californica multiple nucleopolyhedrovirus (rAcMNPV)-infected Sf9 cells, a drop in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0219d9f53481a3d82681ad009bcb1ad3
https://pubmed.ncbi.nlm.nih.gov/25472440
https://pubmed.ncbi.nlm.nih.gov/25472440
Publikováno v:
Biotechnology progress. 28(3)
A critical component of an in vitro production process for baculovirus biopesticides is a growth medium that is efficacious, robust, and inexpensive. An in-house low-cost serum-free medium, VPM3, has been shown to be very promising in supporting Heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9741938d55a2b7e12d1e38a6f019b8cd
https://pubmed.ncbi.nlm.nih.gov/22323401
https://pubmed.ncbi.nlm.nih.gov/22323401