Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Trinh T B Tram"'
Autor:
Trinh T. B. Tram, Vu T. N. Ha, Do D. A. Thu, Tran D. Dinh, Hoang N. Nhung, Nguyen T. Hanh, Nguyen H. Phu, Guy E. Thwaites, Nguyen T. T. Thuong
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Macrophages play a significant role in preventing infection through antimicrobial activities, particularly acidification, and proteolysis. Mycobacterium tuberculosis (Mtb) infection can lead to diverse outcomes, from latent asymptomatic infection to
Externí odkaz:
https://doaj.org/article/57e5b6137b484b70b0f7e049f5e6ac2b
Autor:
Michelle C Sabo, Nguyen T T Thuong, Xuling Chang, Edwin Ardiansyah, Trinh T B Tram, Hoang T Hai, Ho D T Nghia, Nguyen D Bang, Sofiati Dian, A Rizal Ganiem, Shima Shaporifar, Vinod Kumar, Zheng Li, Martin Hibberd, Chiea Chuen Khor, Guy E Thwaites, Dorothee Heemskerk, Arjan van Laarhoven, Reinout van Crevel, Sarah J Dunstan, Javeed A Shah
Publikováno v:
The Journal of Infectious Diseases.
BackgroundThe purpose of this study was to assess if single nucleotide polymorphisms (SNPs) in lung mucins MUC5B and MUC5AC are associated with Mycobacterium tuberculosis outcomes.MethodsIndependent SNPs in MUC5B and MUC5AC (genotyped by Illumina Hum
Autor:
Trinh T. B. Tram, Hoang N. Nhung, Srinivasan Vijay, Hoang T. Hai, Do D. A. Thu, Vu T. N. Ha, Tran D. Dinh, Philip M. Ashton, Nguyen T. Hanh, Nguyen H. Phu, Guy E. Thwaites, Nguyen T. T. Thuong
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
It is uncertain whether differences in Mycobacterium tuberculosis (Mtb) virulence defined in vitro influence clinical tuberculosis pathogenesis, transmission, and mortality. We primarily used a macrophage lysis model to characterize the virulence of
Externí odkaz:
https://doaj.org/article/18fbb6cf8fbc415186c7c6748f21dbb1
Autor:
Srinivasan Vijay, Dao N. Vinh, Hoang T. Hai, Vu T. N. Ha, Vu T. M. Dung, Tran D. Dinh, Hoang N. Nhung, Trinh T. B. Tram, Bree B. Aldridge, Nguyen T. Hanh, Do D. A. Thu, Nguyen H. Phu, Guy E. Thwaites, Nguyen T. T. Thuong
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Mycobacterial cellular variations in growth and division increase heterogeneity in cell length, possibly contributing to cell-to-cell variation in host and antibiotic stress tolerance. This may be one of the factors influencing Mycobacterium tubercul
Externí odkaz:
https://doaj.org/article/b431c721bec8419c95325d5d98464d2d
Autor:
Trinh T. B. Tram, Riwanti Estiasari, Joseph Donovan, Julian Avila-Pacheco, Dao N. Vinh, Reinout van Crevel, Hoang T. Hai, Arjan van Laarhoven, Bachti Alisjahbana, Valerie A. C. M. Koeken, Darma Imran, Vinod Kumar, Clary B. Clish, Nguyen Thuy Thuong Thuong, Sofiati Dian, Raph L. Hamers, Mihai G. Netea, Edwin Ardiansyah, A Rizal Ganiem, Guy E. Thwaites
Publikováno v:
Tuberculosis, 128
There is a clear need to improve host-directed therapy for tuberculous meningitis (TBM), the most severe and deadly manifestation of tuberculosis. Corticosteroids represent the only host-directed therapy of proven benefit in TBM, yet their effect is
Autor:
Trinh T. B. Tram, Do Dang Anh Thu, Guy E. Thwaites, Nguyen Hoan Phu, Hoang N. Nhung, Nguyen Thi Hanh, Vu T. N. Ha, Nguyen Thuy Thuong Thuong, Tran D. Dinh
Macrophages play a significant role in preventing infection through antimicrobial activities, particularly acidification and proteolysis. Mycobacterium tuberculosis infection can lead to diverse outcomes, from latent asymptomatic infection to active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54848dda1d8532e71662a480fb3f6e52
https://doi.org/10.1101/2020.09.14.20194043
https://doi.org/10.1101/2020.09.14.20194043
Autor:
Nguyen Thi Han Ny, Nguyen Thuy Thuong Thuong, Dang Thi Hong Mui, Vu Thi Thu Van, Nguyen Thi Thu Hiep, Le Van Tan, Nguyen Ho Hong Hanh, Guy E. Thwaites, Joseph Donovan, Ho Dang Trung Nghia, Nguyen Hoan Phu, Trinh T. B. Tram
Publikováno v:
The Journal of infectious diseases. 225(9)
Background Helminth infections may modulate the inflammatory response to Mycobacterium tuberculosis and influence disease presentation and outcome. Strongyloides stercoralis is common among populations with high tuberculosis prevalence. Our aim was t
Autor:
Marisa W. Medina, Jerome I. Rotter, Stefan H. Oehlers, David M. Tobin, Elizabeth Theusch, Dennis C. Ko, Yu-Lin Kuang, Trinh T. B. Tram, Eric M. Walton, Liuyang Wang, Colleen M. McClean, Monica I. Alvarez, Sarah J. Dunstan, Nguyen Tran Chinh, Peter M Luo, Luke C. Glover
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Significance Salmonella enterica serovar Typhi ( S . Typhi) causes ∼20 million cases of typhoid fever every year. We carried out a genome-wide association study to identify genetic differences that correlate with the susceptibility of cells from hu
Autor:
Nguyen Van Vinh Chau, Nguyen Thuy Thuong Thuong, Nguyen Phu Huong Lan, Tran Thi Hong Chau, Trinh T. B. Tram, Sarah J. Dunstan, Nguyen Thi Hoang Mai, Vu T. N. Ha, Dorothee Heemskerk, Le Thi Phuong Thao, Lalita Ramakrishnan, Nguyen Duc Bang, Guy E. Thwaites, Maxine Caws, Marcel Wolbers
Publikováno v:
The Journal of Infectious Diseases
Background.: Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that the genotype of leukotriene A4 hydrolase (encoded by LTA4H), which determines inflammator
Autor:
Jeremy Farrar, Tin Aung, Amit Arjyal, Nguyen Phu Huong Lan, Kar Seng Sim, Le Thi Phuong, Trinh T. B. Tram, Phat Voong Vinh, Cameron P. Simmons, Soumya Raychaudhuri, Stephen Baker, Tran Tinh Hien, Nguyen Tran Chinh, Jia Nee Foo, Nga Tran Vu Thieu, Buddha Basnyat, Zheng Li, Nguyen Thi Hue, Abhilasha Karkey, Yukinori Okada, Katherine L. Anders, Do Nu Hon, Sarah J. Dunstan, Martin L. Hibberd, Olita Shilpakar, Christopher M. Parry, Yik Ying Teo, Ha Vinh, Paul I.W. de Bakker, Chiea Chuen Khor, Buhm Han, Mai Ngoc Lanh, Tan Do, Christiane Dolecek, Sabina Dongol, Samir Koirala
Enteric fever affects more than 25 million people annually and results from systemic infection with Salmonella enterica serovar Typhi or Paratyphi pathovars A, B or C1. We conducted a genome-wide association study of 432 individuals with blood cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a97e393a08714303da66f5672ceb1e
https://doi.org/10.1038/ng.3143
https://doi.org/10.1038/ng.3143