The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.

Autor: Zhang Z; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Lyu M; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Han X; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Bandara S; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Cui M; Department of Pharmaceutical Sciences, Northeastern University School of Pharmacy, Boston, MA 02115, USA., Istvan ES; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Geng X; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Tringides ML; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Gregor WD; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Miyagi M; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Oberstaller J; Center for Global Health and Infectious Diseases, Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Suite 404, Tampa, FL 33612, USA., Adams JH; Center for Global Health and Infectious Diseases, Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Suite 404, Tampa, FL 33612, USA., Zhang Y; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Nieman MT; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., von Lintig J; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Goldberg DE; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Yu EW; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Publikováno v: Science advances [Sci Adv] 2024 Dec 20; Vol. 10 (51), pp. eadq6651. Date of Electronic Publication: 2024 Dec 18.

High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.

Autor: Zhang Z; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Tringides ML; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Morgan CE; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Miyagi M; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Mears JA; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Hoppel CL; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Yu EW; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. Electronic address: edward.w.yu@case.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2023 Dec; Vol. 22 (12), pp. 100666. Date of Electronic Publication: 2023 Oct 14.

Crystal structure of the transcriptional regulator Rv0678 of Mycobacterium tuberculosis.

Autor: Radhakrishnan A; From the Department of Chemistry and., Kumar N; From the Department of Chemistry and., Wright CC; the Department of Molecular Microbiology and Immunology, Oregon Health and Sciences University, Portland, Oregon 97239, and., Chou TH; the Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011., Tringides ML; From the Department of Chemistry and., Bolla JR; From the Department of Chemistry and., Lei HT; From the Department of Chemistry and., Rajashankar KR; the Northeastern Collaborative Access Team and Department of Chemistry and Chemical Biology, Cornell University, Argonne National Laboratory, Argonne, Illinois 60439., Su CC; the Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011., Purdy GE; the Department of Molecular Microbiology and Immunology, Oregon Health and Sciences University, Portland, Oregon 97239, and., Yu EW; From the Department of Chemistry and the Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, ewyu@iastate.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2014 Jun 06; Vol. 289 (23), pp. 16526-40. Date of Electronic Publication: 2014 Apr 15.