Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Trine Salomón"'
Autor:
Rikke Nielsen, Kristian M. Jacobsen, Morten Muhlig Nielsen, Jakob Skou Pedersen, Carsten Scavenius, Camilla Bak Nielsen, Thomas B. Poulsen, Peter Bross, Nikolaj L. Villadsen, Erik Ilsø Christensen, Jens Overgaard, Jan J. Enghild, Trine Salomón, Michael R. Horsman, Christian Sibbersen, Paula Fernandez Guerra, Jørgen Frøkiær, Thomas Tørring, Mogens Johannsen, Morten Busk, Michail Tsakos
Publikováno v:
Jacobsen, K M, Villadsen, N L, Tørring, T, Nielsen, C B, Salomón, T, Nielsen, M M, Tsakos, M, Sibbersen, C, Scavenius, C, Nielsen, R, Christensen, E I, Guerra, P F, Bross, P, Pedersen, J S, Enghild, J J, Johannsen, M, Frøkiær, J, Overgaard, J, Horsman, M R, Busk, M & Poulsen, T B 2018, ' APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells ', Cell Chemical Biology, vol. 25, no. 11, pp. 1337-1349.e12 . https://doi.org/10.1016/j.chembiol.2018.07.010
The natural product family of macrocyclic lipodepsipeptides containing the 4-amido-2,4-pentadienoate functionality possesses intriguing cytotoxic selectivity toward hypoxic cancer cells. These subpopulations of cancer cells display increased metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704e820d6477fd45a78aaa387061c19f
https://pubmed.ncbi.nlm.nih.gov/30445051
https://pubmed.ncbi.nlm.nih.gov/30445051
Autor:
Karl Anker Jørgensen, Ulrik B. Keiding, Thomas B. Poulsen, Rasmus Kold-Christensen, Emil F. Holmquist, Mogens Johannsen, Peter Kristensen, Trine Salomón
Publikováno v:
Holmquist, E F, B Keiding, U, Kold-Christensen, R, Salomón, T, Jørgensen, K A, Kristensen, P, Poulsen, T B & Johannsen, M 2017, ' ReactELISA : Monitoring a Carbon Nucleophilic Metabolite by ELISA-a Study of Lipid Metabolism ', Analytical Chemistry, vol. 89, no. 9, pp. 5066-5071 . https://doi.org/10.1021/acs.analchem.7b00507
We here present a conceptually novel reaction-based ELISA principle (ReactELISA) for quantitation of the carbon nucleophilic lipid metabolite acetoacetate. Key to the assay is the utilization of a highly chemoselective Friedländer reaction that capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775869467eb937a69f4b5cbeb1a30b3e
https://pubmed.ncbi.nlm.nih.gov/28376300
https://pubmed.ncbi.nlm.nih.gov/28376300
Autor:
Karl Anker Jørgensen, Mogens Johannsen, Thomas B. Poulsen, Niels Møller, Thomas Schmidt Voss, Johan Palmfeldt, Jakob Hansen, Mads Svart, Trine Salomón, Dieter Britz, Niels Gregersen, Christian Sibbersen
Publikováno v:
Salomon, T, Sibbersen, C, Hansen, J, Britz, D H, Svart, M, Voss, T S, Møller, N, Gregersen, N, Jørgensen, K A, Palmfeldt, J, Poulsen, T & Johannsen, M 2017, ' Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis ', Cell Chemical Biology, bind 24, nr. 8, s. 935-943 . https://doi.org/10.1016/j.chembiol.2017.07.012
The a-oxoaldehyde methylglyoxal is a ubiquitousand highly reactive metabolite known to be involvedin aging- and diabetes-related diseases. If notdetoxified by the endogenous glyoxalase system,it exerts its detrimental effects primarily by reactingwit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9e5c70753195fd76dcf87e670b0749
https://doi.org/10.1016/j.chembiol.2017.07.012
https://doi.org/10.1016/j.chembiol.2017.07.012