Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Trine Holt Edwin"'
Autor:
Anne-Brita Knapskog, Trine Holt Edwin, Per Magne Ueland, Arve Ulvik, Evandro Fei Fang, Rannveig Sakshaug Eldholm, Nathalie Bodd Halaas, Lasse M. Giil, Ingvild Saltvedt, Leiv Otto Watne, Mari Aksnes
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Sex differences in neuroinflammation could contribute to women’s increased risk of Alzheimer’s disease (AD), providing rationale for exploring sex-specific AD biomarkers. In AD, dysregulation of the kynurenine pathway (KP) con
Externí odkaz:
https://doaj.org/article/5756027d5d874a8f9b16adf7278e48c7
Autor:
Mari Aksnes, Mari Haavig Schibstad, Farrukh Abbas Chaudhry, Bjørn Erik Neerland, Gideon Caplan, Ingvild Saltvedt, Rannveig S. Eldholm, Marius Myrstad, Trine Holt Edwin, Karin Persson, Ane-Victoria Idland, Christian Thomas Pollmann, Roy Bjørkholt Olsen, Torgeir Bruun Wyller, Henrik Zetterberg, Emma Cunningham, Leiv Otto Watne
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-10 (2024)
Abstract Background The aetiology of delirium is not known, but pre-existing cognitive impairment is a predisposing factor. Here we explore the associations between delirium and cerebrospinal fluid (CSF) levels of matrix metalloproteinases (MMPs) and
Externí odkaz:
https://doaj.org/article/d7f65a539b7b480e9278bc2075d78d8f
Autor:
Karin Persson, Esten H. Leonardsen, Trine Holt Edwin, Anne-Brita Knapskog, Gro Gujord Tangen, Geir Selbæk, Thomas Wolfers, Lars T. Westlye, Knut Engedal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The aim of this study was to assess the diagnostic validity of a deep learning-based method estimating brain age based on magnetic resonance imaging (MRI) and to compare it with volumetrics obtained using NeuroQuant (NQ) in a clinical cohort
Externí odkaz:
https://doaj.org/article/5747eaade748427f92fd3ca65956baf6
Autor:
Karin Persson, Maria L. Barca, Trine Holt Edwin, Lena Cavallin‐Eklund, Gro Gujord Tangen, Hanneke F. M. Rhodius‐Meester, Geir Selbæk, Anne‐Brita Knapskog, Knut Engedal
Publikováno v:
Brain and Behavior, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background and purpose The aims were to compare the novel regional brain volumetric measures derived by the automatic software NeuroQuant (NQ) with clinically used visual rating scales of medial temporal lobe atrophy (MTA), global cortical a
Externí odkaz:
https://doaj.org/article/369f616bc1994ffa91e7d0adcf44bceb
Autor:
Heidi Vihovde Sandvig, Trine Holt Edwin, Stina Aam, Katinka N. Alme, Stian Lydersen, Tom Eirik Mollnes, Bjørn Heine Strand, Per Magne Ueland, Arve Ulvik, Torgeir Wethal, Anne-Brita Knapskog, Ingvild Saltvedt
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100315- (2024)
Introduction: We have previously shown that cytokines, the complement system, neopterin, the kynurenine pathway, and vitamin B6-indexes were associated with post-stroke cognitive impairment. In this study, we aimed to investigate whether these biomar
Externí odkaz:
https://doaj.org/article/c9ace9687a0d4ebfb818cc71d80cf41a
Autor:
Mari Aksnes, Hans Christian D. Aass, Ann Tiiman, Trine Holt Edwin, Lars Terenius, Nenad Bogdanović, Vladana Vukojević, Anne-Brita Knapskog
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-10 (2021)
Abstract Background The aggregation of amyloid β (Aβ) is central in the pathogenesis of Alzheimer’s disease (AD). Recently it has been shown that specifically, larger, Thioflavin T-binding Aβ aggregates are associated with increased neuroinflamm
Externí odkaz:
https://doaj.org/article/1249e7e2748045559a301e9f602c2499
Autor:
Mari Aksnes, Ann Tiiman, Trine Holt Edwin, Lars Terenius, Nenad Bogdanović, Vladana Vukojević, Anne-Brita Knapskog
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2021)
Accurate biomarkers of Alzheimer’s disease (AD) are essential for early diagnosis and intervention. Available biomarkers are not sufficient to permit the monitoring of AD progression over time, and additional biomarkers are required. Measures of ag
Externí odkaz:
https://doaj.org/article/41fe36e1406a4a0f8afcd14a720dca62
Autor:
Marit Mjørud, Geir Selbæk, Espen Bjertness, Trine Holt Edwin, Knut Engedal, Anne-Brita Knapskog, Bjørn Heine Strand
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243513 (2020)
ObjectivesTo estimate transition times from dementia diagnosis to nursing-home (NH) admission or death and to examine whether sex, education, marital status, level of cognitive impairment and dementia aetiology are associated with transition times.De
Externí odkaz:
https://doaj.org/article/46620b96789342fcadc9f70d7c647d7e
Autor:
Trine Holt Edwin, Kristi Henjum, Lars N.G. Nilsson, Leiv Otto Watne, Karin Persson, Rannveig Sakshaug Eldholm, Ingvild Saltvedt, Nathalie Bodd Halaas, Geir Selbæk, Knut Engedal, Bjørn Heine Strand, Anne‐Brita Knapskog
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 (sTREM2), a proxy of mi
Externí odkaz:
https://doaj.org/article/ccb8917943a6483ab04693652550c057
Autor:
Ebba Gløersen Müller, Trine Holt Edwin, Caroline Stokke, Sigrid Stensby Navelsaker, Almira Babovic, Nenad Bogdanovic, Anne Brita Knapskog, Mona Elisabeth Revheim
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221365 (2019)
BackgroundAlzheimer's disease (AD) remains a clinical diagnosis but biomarkers from cerebrospinal fluid (CSF) and more lately amyloid imaging with positron emission tomography (PET), are important to support a diagnosis of AD.ObjectiveTo compare amyl
Externí odkaz:
https://doaj.org/article/230848bd898b4f3b974897f1b97b3b57