Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Trine Celius"'
Publikováno v:
Toxicological Sciences. 138:89-103
In this study, we used zinc finger nuclease-mediated knockout of the aryl hydrocarbon receptor (AHR) or AHR nuclear translocator (ARNT) in MCF7 and AHR knockout in MDA-MB-231 human breast cancer cells to investigate cross talk among AHR, ARNT, and es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6512bcb277f0891a41dbc22984355b7
https://doi.org/10.1093/toxsci/kft274
https://doi.org/10.1093/toxsci/kft274
Autor:
Agnes L. Forgacs, Jason Matthews, Trine Celius, Patricia A. Harper, Raymond Lo, Timothy R. Zacharewski, Laura MacPherson, Edward Dere
Publikováno v:
Toxicology and Applied Pharmacology. 257:38-47
Genome-wide, promoter-focused ChIP-chip analysis of hepatic aryl hydrocarbon receptor (AHR) binding sites was conducted in 8-week old female C57BL/6 treated with 30 μg/kg/body weight 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) for 2 h and 24 h. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f151cee37169740388ab113796e7ea
https://doi.org/10.1016/j.taap.2011.08.016
https://doi.org/10.1016/j.taap.2011.08.016
Publikováno v:
Biochemical and Biophysical Research Communications. 410:859-865
The aryl hydrocarbon receptor (AHR) mediates the toxic effects of halogenated aromatic hydrocarbons (HAHs), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD), 2,3,4,7,8-pentachlorodibenzofuran (2,3,4,7,8-PeCDF) and 2,3,7,8-tetrachlorodibenzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f49188e653cc9729c9c2e751b0bfe
https://doi.org/10.1016/j.bbrc.2011.06.079
https://doi.org/10.1016/j.bbrc.2011.06.079
Autor:
Allan B. Okey, Andrea Pansoy, Jason Matthews, Sharon K. Krueger, David E. Williams, Trine Celius, Marilyn C. Henderson
Publikováno v:
Toxicology and Applied Pharmacology. 247:60-69
Flavin-containing monooxygenases often are thought not to be inducible but we recently demonstrated aryl hydrocarbon receptor (AHR)-dependent induction of FMO mRNAs in mouse liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (Celius et al., Drug Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361d76459794ed06ac76146978249d0d
https://doi.org/10.1016/j.taap.2010.05.018
https://doi.org/10.1016/j.taap.2010.05.018
Publikováno v:
Environmental Toxicology and Pharmacology. 19:57-70
Perfluorooctane sulfonic acid (PFOS) is widely distributed in the environment including in the tissues of wildlife and humans, however, its mechanism of action remains unclear. Here, the Affymetrix rat genome U34A genechip was used to identify altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4f266fec0d1bc49ef2a46312db0c2c
https://doi.org/10.1016/j.etap.2004.04.008
https://doi.org/10.1016/j.etap.2004.04.008
Autor:
Cora J. Fong, Yue-Wern Huang, Timothy R. Zacharewski, Kirsten C. Fertuck, Jason Matthews, Trine Celius
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 82:181-194
The ability of 14 structurally diverse estrogenic compounds to induce reporter gene expression mediated by estrogen receptors (ERs) from different species was examined. MCF-7 cells were transiently transfected with a Gal4-regulated luciferase reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa39668ed9525139a1c45f39efa8a70
https://doi.org/10.1016/s0960-0760(02)00159-0
https://doi.org/10.1016/s0960-0760(02)00159-0
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 74:223-234
The study investigated the ability of 34 natural and synthetic chemicals to compete with [3H]17beta-estradiol (E2) for binding to bacterially expressed glutathione-S-transferase (GST)-estrogen receptors (ER) fusion proteins from five different specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869c952123d0b465a74b44ba76406e37
https://doi.org/10.1016/s0960-0760(00)00126-6
https://doi.org/10.1016/s0960-0760(00)00126-6
Publikováno v:
Aquatic Toxicology. 49:159-170
Zonagenesis (zona radiata protein synthesis) and vitellogenesis (yolk protein synthesis) are two reproductive responses that are integral aspects of fish oogenesis. This study examines the responses of eggshell zona radiata proteins (Zrp) and vitello
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b077ed0873d54ba92809a24ac873513
https://doi.org/10.1016/s0166-445x(99)00083-1
https://doi.org/10.1016/s0166-445x(99)00083-1
Publikováno v:
Environmental Health Perspectives
Mounting evidence confirms that hepatic biosynthetic processes are essential for female sexual maturation in fish, which is directly controlled by estrogens. These oogenetic events (zonagenesis and vitellogenesis) are induced in both sexes by estroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7c46de311b4a5b452d2b7e650bc922
https://doi.org/10.1289/ehp.9910763
https://doi.org/10.1289/ehp.9910763
Autor:
Trine Celius, Bernt T. Walther
Publikováno v:
The Journal of Experimental Zoology. 281:346-353
In Atlantic salmon (Salmo salar L) female sexual maturation entails both zonagenesis and vitellogenesis, both of which are controlled by increasing levels of estradiol-17 beta (E2). Antibodies against salmon zona radiata proteins (eggshell zr-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7481c0f3bcaff254bdfc8488ea0b04fa
https://doi.org/10.1002/(sici)1097-010x(19980701)281:4<346::aid-jez9>3.0.co
https://doi.org/10.1002/(sici)1097-010x(19980701)281:4<346::aid-jez9>3.0.co