Robust Porcine GFR Measurement with Radiotracers and Only Late Blood Samples

Autor: Lars Jødal, Juan Ignacio Brignone, Pui-Ki Chan Ladefoged, Lars Lund, Trine Borup Andersen

Publikováno v: Biologics, Vol 3, Iss 4, Pp 296-307 (2023)

(1) Pigs are physiologically very relevant as animal models of human physiology. Radiotracer methods for porcine GFR (glomerular filtration rate) determination exist but require full-curve blood sampling or the application of correction formulas, whi

Externí odkaz: https://doaj.org/article/bae1b7d003a84d76bcdf16674c3f9cd2

Nuclear imaging methods for the prediction of postoperative morbidity and mortality in patients undergoing localized, liver-directed treatments: a systematic review

Autor: Caroline Espersen, Lise Borgwardt, Peter Nørgaard Larsen, Trine Borup Andersen, Louise Stenholt, Lars Jelstrup Petersen

Publikováno v: EJNMMI Research, Vol 10, Iss 1, Pp 1-22 (2020)

Abstract Background Several nuclear imaging methods may predict postoperative liver function and outcome, but none has achieved recommendations in clinical guidelines. The purpose of this systematic review was to summarize the existing knowledge on t

Externí odkaz: https://doaj.org/article/7d93d044cd8b460a8e4fed10909f58ce

Efficacy and safety of colesevelam for the treatment of bile acid diarrhoea:a double-blind, randomised, placebo-controlled, phase 4 clinical trial

Autor: Christian Borup, Lars Vinter-Jensen, Søren Peter German Jørgensen, Signe Wildt, Jesper Graff, Tine Gregersen, Anna Zaremba, Trine Borup Andersen, Camilla Nøjgaard, Hans Bording Timm, Dominique Rainteau, Svend Høime Hansen, Jüri Johannes Rumessen, Lars Kristian Munck

Publikováno v: Borup, C, Vinter-Jensen, L, Jørgensen, S P G, Wildt, S, Graff, J, Gregersen, T, Zaremba, A, Borup Andersen, T, Nøjgaard, C, Timm, H B, Rainteau, D, Hansen, S H, Rumessen, J J & Munck, L K 2023, ' Efficacy and safety of colesevelam for the treatment of bile acid diarrhoea : a double-blind, randomised, placebo-controlled, phase 4 clinical trial ', The Lancet Gastroenterology & Hepatology, vol. 8, no. 4, pp. 321-331 . https://doi.org/10.1016/S2468-1253(22)00401-0
Borup, C, Vinter-Jensen, L, Jørgensen, S P G, Wildt, S, Graff, J, Gregersen, T, Zaremba, A, Borup Andersen, T, Nøjgaard, C, Timm, H B, Rainteau, D, Hansen, S H, Rumessen, J J & Munck, L K 2023, ' Efficacy and safety of colesevelam for the treatment of bile acid diarrhoea : a double-blind, randomised, placebo-controlled, phase 4 clinical trial ', The Lancet Gastroenterology and Hepatology, vol. 8, no. 4, pp. 321-331 . https://doi.org/10.1016/S2468-1253(22)00401-0

BACKGROUND: Bile acid diarrhoea is a common but overlooked cause of chronic watery diarrhoea. Plasma 7α-hydroxy-4-cholesten-3-one (C4) is an alternative to the gold standard tauroselcholic [75Se] acid (SeHCAT) test. Low-certainty evidence supports s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf41f7b32203fdb9313268e555c9edb
https://vbn.aau.dk/da/publications/c80274c8-3cd1-40e6-abf9-e3d045ae85b4

Comparison of nuclear imaging techniques and volumetric imaging for the prediction of postoperative mortality and liver failure in patients undergoing localized liver-directed treatments:a systematic review

Autor: Trine Borup Andersen, Louise Stenholt, Lise Borgwardt, Peter Nørgaard Larsen, Caroline Espersen, Lars Jelstrup Petersen

Publikováno v: Espersen, C, Borgwardt, L, Larsen, P N, Andersen, T B, Stenholt, L & Petersen, L J 2021, ' Comparison of nuclear imaging techniques and volumetric imaging for the prediction of postoperative mortality and liver failure in patients undergoing localized liver-directed treatments : a systematic review ', EJNMMI Research, vol. 11, no. 1, 80 . https://doi.org/10.1186/s13550-021-00816-4
EJNMMI Research
EJNMMI Research, Vol 11, Iss 1, Pp 1-17 (2021)

Background/aims Although volumetric imaging by computed tomography (CT) is the gold standard for preoperative assessment of the future liver remnant, nuclear imaging studies have shown promising data. This systematic review summarized the results fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5ee1eec0e3b97c5f0b865c10a47d68
https://vbn.aau.dk/da/publications/af8bbd2e-9ab5-4b69-8c92-b99893bb0890

Nuclear imaging methods for the prediction of postoperative morbidity and mortality in patients undergoing localized, liver-directed treatments:a systematic review

Autor: Louise Stenholt, Trine Borup Andersen, Peter Nørgaard Larsen, Lise Borgwardt, Caroline Espersen, Lars Jelstrup Petersen

Publikováno v: Espersen, C, Borgwardt, L, Larsen, P N, Andersen, T B, Stenholt, L & Petersen, L J 2020, ' Nuclear imaging methods for the prediction of postoperative morbidity and mortality in patients undergoing localized, liver-directed treatments : a systematic review ', EJNMMI Research, vol. 10, no. 1, 101 . https://doi.org/10.1186/s13550-020-00687-1
EJNMMI Research
EJNMMI Research, Vol 10, Iss 1, Pp 1-22 (2020)

Background Several nuclear imaging methods may predict postoperative liver function and outcome, but none has achieved recommendations in clinical guidelines. The purpose of this systematic review was to summarize the existing knowledge on this topic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a026f63d7bbf7a1098c5d62e838117
https://vbn.aau.dk/ws/files/353496778/Espersen_et_al_2020_Nuclear_imaging_methods_for_the_prediction_of_postoperative_morbidity_and_mortality_in_patients_undergoing_localized_liver_directed_treatments.pdf