Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Trine, Henriksen"'
Autor:
Anders Jorgensen, Kristin Köhler-Forsberg, Trine Henriksen, Allan Weimann, Ivan Brandslund, Christina Ellervik, Henrik E. Poulsen, Gitte Moos Knudsen, Vibe G. Frokjaer, Martin B. Jorgensen
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Previous studies have indicated that antidepressants that inhibit the serotonin transporter reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a range of age-related pathophysiological processes. Here, we st
Externí odkaz:
https://doaj.org/article/54b9a33f8eb442f8986956297ef339be
Autor:
Suvanjaa Sivalingam, Emil List Larsen, Daniel H. van Raalte, Marcel H. A. Muskiet, Mark M. Smits, Lennart Tonneijck, Jaap A. Joles, Bernt Johan von Scholten, Emilie Hein Zobel, Frederik Persson, Trine Henriksen, Lars Jorge Diaz, Tine W. Hansen, Henrik Enghusen Poulsen, Peter Rossing
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Glucagon-like peptide 1 receptor agonists have shown cardioprotective effects which have been suggested to be mediated through inhibition of oxidative stress. We investigated the effect of treatment with a glucagon-like peptide 1 receptor ag
Externí odkaz:
https://doaj.org/article/3bcc699d77684b339336dcb21eb97295
Autor:
Elin Rebecka Carlsson, Mogens Fenger, Trine Henriksen, Laura Kofoed Kjaer, Dorte Worm, Dorte Lindqvist Hansen, Sten Madsbad, Henrik Enghusen Poulsen
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243918 (2020)
Increased oxidative stress in obesity and diabetes is associated with morbidity and mortality risks. Levels of oxidative damage to DNA and RNA can be estimated through measurement of 8-oxo-7,8-dihydro-2´-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydr
Externí odkaz:
https://doaj.org/article/c6294d46765f4fab9443134a31862808
Autor:
Sanne Tofte Rasmussen, Jon Trærup Andersen, Torben Kjær Nielsen, Vanja Cejvanovic, Kasper Meidahl Petersen, Trine Henriksen, Allan Weimann, Jens Lykkesfeldt, Henrik Enghusen Poulsen
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 32-38 (2016)
Simvastatin reduces the blood concentration of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis, and thereby reduces the risk of cardiovascular disease. In addition, simvastatin t
Externí odkaz:
https://doaj.org/article/63061fb5997b4904b846c6aade416065
Autor:
Anders Jorgensen, Ivan Brandslund, Christina Ellervik, Trine Henriksen, Allan Weimann, Per Kragh Andersen, Henrik E. Poulsen
Publikováno v:
Jorgensen, A, Brandslund, I, Ellervik, C, Henriksen, T, Weimann, A, Andersen, P K & Poulsen, H E 2023, ' Specific prediction of mortality by oxidative stress-induced damage to RNA vs. DNA in humans ', Aging Cell, vol. 22, no. 6, e13839 . https://doi.org/10.1111/acel.13839
Modifications of nucleic acids (DNA and RNA) from oxidative stress is a potential driver of aging per se and of mortality in age-associated medical disorders such as type 2 diabetes (T2D). In a human cohort, we found a strong prediction of all-cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a79faa58b6bc5ff9ffa714430cafb4b
https://curis.ku.dk/ws/files/356957167/Fulltext.pdf
https://curis.ku.dk/ws/files/356957167/Fulltext.pdf
Publikováno v:
Free Radical Biology and Medicine. 172:350-357
Among markers for oxidative stress urinary excretion 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) and 8-oxo-7,8-dihydro-guanosine (8-oxoGuo) have been widely used in controlled and epidemiological studies, and are considered to represent intracell
Autor:
Kasper Broedbaek, Volkert Siersma, Trine Henriksen, Allan Weimann, Morten Petersen, Jon T. Andersen, Espen Jimenez-Solem, Lars J. Hansen, Jan Erik Henriksen, Steen J. Bonnema, Niels de Fine Olivarius, Søren Friis, Henrik E. Poulsen
Publikováno v:
Redox Biology, Vol 4, Iss C, Pp 34-39 (2015)
Aims/hypothesis: We investigated whether urinary markers of nucleic acid oxidation are associated with an increased risk of cancer in type 2 diabetes patients. Methods: Urine samples from 1381 newly diagnosed diabetes patients were assayed for the ox
Externí odkaz:
https://doaj.org/article/c40ff9737d4e4878950f45fe74be1b85
Autor:
Ben Schöttker, Emil L. Larsen, Allan Weimann, Trine Henriksen, Hermann Brenner, Henrik E. Poulsen
Publikováno v:
Free radical biologymedicine. 183
To evaluate the association of urinary oxidized guanine/guanosine (OxGuo) levels with incident type 2 diabetes (T2D) among older adults.A nested case-control design was applied with 440 cases of incident T2D and 440 controls, randomly sampled from al
Autor:
Anders Jorgensen, Kristin Köhler-Forsberg, Trine Henriksen, Allan Weimann, Ivan Brandslund, Christina Ellervik, Henrik E. Poulsen, Gitte Moos Knudsen, Vibe G. Frokjaer, Martin B. Jorgensen
Publikováno v:
Jorgensen, A, Köhler-Forsberg, K, Henriksen, T, Weimann, A, Brandslund, I, Ellervik, C, Poulsen, H E, Knudsen, G M, Frokjaer, V G & Jorgensen, M B 2022, ' Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression ', Translational Psychiatry, vol. 12, 204 . https://doi.org/10.1038/s41398-022-01969-z
Previous studies have indicated that antidepressants that inhibit the serotonin transporter reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a range of age-related pathophysiological processes. Here, we studied the
Autor:
Mark M. Smits, Emil List Larsen, Emilie H. Zobel, Daniël H. van Raalte, Bernt Johan von Scholten, Lennart Tonneijck, Suvanjaa Sivalingam, Tine W. Hansen, Marcel H. A. Muskiet, Jaap A. Joles, Frederik Persson, Lars Jorge Diaz, Henrik E. Poulsen, Trine Henriksen, Peter Rossing
Publikováno v:
Scientific Reports
Scientific Reports, 11(1):10624. Nature Publishing Group
Sivalingam, S, Larsen, E L, van Raalte, D H, Muskiet, M H A, Smits, M M, Tonneijck, L, Joles, J A, von Scholten, B J, Zobel, E H, Persson, F, Henriksen, T, Diaz, L J, Hansen, T W, Poulsen, H E & Rossing, P 2021, ' The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes ', Scientific Reports, vol. 11, no. 1, 10624 . https://doi.org/10.1038/s41598-021-90191-w
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, 11(1):10624. Nature Publishing Group
Sivalingam, S, Larsen, E L, van Raalte, D H, Muskiet, M H A, Smits, M M, Tonneijck, L, Joles, J A, von Scholten, B J, Zobel, E H, Persson, F, Henriksen, T, Diaz, L J, Hansen, T W, Poulsen, H E & Rossing, P 2021, ' The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes ', Scientific Reports, vol. 11, no. 1, 10624 . https://doi.org/10.1038/s41598-021-90191-w
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Glucagon-like peptide 1 receptor agonists have shown cardioprotective effects which have been suggested to be mediated through inhibition of oxidative stress. We investigated the effect of treatment with a glucagon-like peptide 1 receptor agonist (li