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Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

Autor: Zhao, W., Rasheed, A., Tikkanen, E., Lee, J.J., Butterworth, A.S., Howson, J.M.M., Assimes, T.L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J.C., Chen, P., Sapkota, B.R., Shah, N., Jabeen, S., Surendran, P., Lu, Y.C., Zhang, W.H., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N.H., Yaqoob, Z., Saghir, T., Rizvi, S.N.H., Memon, A., Rasheed, S.Z., Memon, F.U.R., Mehmood, K., Ahmed, N., Qureshi, I.H., Tanveer-us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J.Z., Sheu, W.H.H., Guo, X.Q., Hsiung, C.A., Juang, J.M.J., Taylor, K.D., Hung, Y.J., Lee, W.J., Quertermous, T., Lee, I.T., Hsu, C.C., Bottinger, E.P., Ralhan, S., Teo, Y.Y., Wang, T.D., Alam, D.S., Angelantonio, E. di, Epstein, S., Nielsen, S.F., Nordestgaard, B.G., Tybjaerg-Hansen, A., Young, R., Benn, M., Frikke-Schmidt, R., Kamstrup, P.R., Biobank, M., Jukema, J.W., Sattar, N., Smit, R., Chung, R.H., Liang, K.W., Anand, S., Sanghera, D.K., Ripatti, S., Loos, R.J.F., Kooner, J.S., Tai, E.S., Rotter, J.I., Chen, Y.D.I., Frossard, P., Maeda, S., Kadowaki, T., Reilly, M., Pare, G., Melander, O., Salomaa, V., Rader, D.J., Danesh, J., Voight, B.F., Saleheen, D., CHD Exome Consortium, EPIC-CVD Consortium, EPIC-Interact Consortium

Publikováno v: Nature Genetics, 49(10), 1450
Nature genetics
Nature genetics, vol 49, iss 10

Danish Saleheen, Benjamin Voight and colleagues perform genome-wide analysis of multi-ancestry cohorts to identify genetic associations with type 2 diabetes (T2D) and coronary heart disease (CHD). They find novel loci and show that 24% of T2D loci ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3caa34b8b3ba5e80982419c873b247
http://hdl.handle.net/1887/114868

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