ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.

Autor: Rubina A; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Patel M; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Nightingale K; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Potts M; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Fielding CA; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Kollnberger S; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Lau B; Centre for Virus Research, University of Glasgow, Glasgow G12 8TA, United Kingdom., Ladell K; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Miners KL; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Nichols J; Centre for Virus Research, University of Glasgow, Glasgow G12 8TA, United Kingdom., Nobre L; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Roberts D; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Trinca TM; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Twohig JP; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Vlahava VM; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Davison AJ; Centre for Virus Research, University of Glasgow, Glasgow G12 8TA, United Kingdom., Price DA; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Tomasec P; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Wilkinson GWG; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Weekes MP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Stanton RJ; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Wang ECY; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 15; Vol. 120 (33), pp. e2303155120. Date of Electronic Publication: 2023 Aug 10.