Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Trinath, Jamma"'
Autor:
Ashna Fathima, Trinath Jamma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Long-standing chronic inflammation of the digestive tract leads to Inflammatory Bowel Diseases (IBD), comprising Crohn’s Disease (CD) and Ulcerative colitis (UC). The persistent prevalence of these conditions in the gut is a predisposing f
Externí odkaz:
https://doaj.org/article/e76c2fb8d7c04efab19f63a4f53ce3aa
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Withanolides are a group of naturally occurring plant-based small molecules known for their wide range of host cellular functions. The anticancer potential of withanolides has been explored in varying cancer cell lines in vitro. Based on our prior st
Externí odkaz:
https://doaj.org/article/f31299d2c3444217993c49f779e8efb7
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The intestinal tract encompasses one of the largest mucosal surfaces with a well-structured layer of intestinal epithelial cells supported by a network of underlying lamina propria immune cells maintaining barrier integrity. The commensal microflora
Externí odkaz:
https://doaj.org/article/c3a77462630a4d54bca172d3c0ab2c56
Autor:
Purbali Chakraborty, Syeda Lubna, Shouvik Bhuin, Deepika K., Manab Chakravarty, Trinath Jamma, Perumal Yogeeswari
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The pursuit of small molecule inhibitors targeting hexokinase 2 (HK2) has significantly captivated the field of cancer drug discovery. Nevertheless, the creation of selective inhibitors aimed at specific isoforms of hexokinase (HK) remains a formidab
Externí odkaz:
https://doaj.org/article/794a70d147954a7fa5aa5e05cc2fa07e
Autor:
Khetmalis, Yogesh Mahadu, Shree, Bakhya, Kumar, Boddupalli Venkata Siva, Schweipert, Markus, Debarnot, Cécile, Ashna, Fathima, Sankaranarayanan, Murugesan, Trinath, Jamma, Sharma, Vivek, Meyer-Almes, Franz-Josef, Sekhar, Kondapalli Venkata Gowri Chandra
Publikováno v:
In Journal of Molecular Structure 15 April 2023 1278
Publikováno v:
Cell Stress & Chaperones, 2018 May 01. 23(3), 441-454.
Externí odkaz:
https://www.jstor.org/stable/44851644
Autor:
Sonal Saxena, Pranay Amruth Maroju, Sumana Choudhury, Vidhya Chitta Voina, Poonam Naik, Kavitha Gowdhaman, Poornima Kkani, Kiranmai Chennoju, S. Ganesh Kumar, C. Ramasubramanian, G. Prasad Rao, Trinath Jamma, Kumar Pranav Narayan, K. Naga Mohan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://doaj.org/article/28798b94df534441895eee949185e1f1
Autor:
Sekhar, Yogesh Mahadu Khetmalis, Ashna Fathima, Markus Schweipert, Cécile Debarnot, Naga Venkata Madhusudhan Rao Bandaru, Sankaranarayanan Murugesan, Trinath Jamma, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 11044
A series of novel quinazoline-4-(3H)-one derivatives were designed and synthesized as histone deacetylase 6 (HDAC6) inhibitors based on novel quinazoline-4-(3H)-one as the cap group and benzhydroxamic acid as the linker and metal-binding group. A tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::afcdc1716c651814e326e2e6bf2d72e8
Publikováno v:
Future Medicinal Chemistry. 14:463-478
Background: Epidermal growth factor receptor-tyrosine kinase (EGFR-TK) is a well-known hallmark of oral and oropharyngeal cancers, as its overexpression leads to poor prognosis and malignancy. The activating EGFR mutations (particularly T790M and L85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f65cfaeee4086be67f76ccfe45e4ab0
https://doi.org/10.4155/fmc-2021-0205
https://doi.org/10.4155/fmc-2021-0205
Publikováno v:
Advanced Therapeutics. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6e1c87699e79501ce9c26d8b8e0bf1
https://doi.org/10.1002/adtp.202300015
https://doi.org/10.1002/adtp.202300015