Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Trina Slabiak"'
Autor:
Marjorie Ison-Dugenny, Yi Shao, Trina Slabiak, Michael Rowe, Edward Moler, Christie Fanton, Thomas G. Gesner, Katherine Rendahl, Susan K. De Long, Mary Lee MacKichan
Publikováno v:
SLAS Discovery. 11:792-806
Chk1 is a key regulator of the S and G2/M checkpoints and is activated following DNA damage by agents such as the topoisomerase I inhibitor camptothecin (CPT). It has been proposed that Chk1 inhibitors used in combination with such a DNA damaging age
Autor:
David B. Ring, Isa Samuels, Kirk W. Johnson, Erik J. Henriksen, Dane Goff, Allan S. Wagman, Stephen D. Harrison, Trina Slabiak, John W. Reeder, Mary Ellen Wernette Hammond, John M. Nuss, Sylvia Ma, Tyson R. Kinnick
Publikováno v:
Diabetes. 52(3)
Insulin resistance plays a central role in the development of type 2 diabetes, but the precise defects in insulin action remain to be elucidated. Glycogen synthase kinase 3 (GSK-3) can negatively regulate several aspects of insulin signaling, and ele
Publikováno v:
Nature. 336:259-261
Follicular lymphoma is the most common human B-cell malignancy in the United States and Western Europe1. Most of the tumours contain t(14;18) chromosome translocations involving the human bcl-2 gene2–5. Translocation of bcl-2 sequences from chromos