Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Trina B, Allen"'
Autor:
Lawrence J. Shampine, Jason D. Kilts, Brian T. Cuffe, Charlotte E Dunn, Gillian Parke, Steven T. Szabo, Susan H. O’Loughlin, Karen D. Smith, Jennifer C. Naylor, Trina B. Allen, Emily G. Telford-Marx, Christine E. Marx, H. Ryan Wagner
Publikováno v:
JAMA Network Open. 3:e200287
Importance In response to the national opioid public health crisis, there is an urgent need to develop nonopioid solutions for effective pain management. Neurosteroids are endogenous molecules with pleotropic actions that show promise for safe and ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c3a6692163ce463f112075620d6216
https://doi.org/10.1001/jamanetworkopen.2020.0287
https://doi.org/10.1001/jamanetworkopen.2020.0287
Autor:
Joseph Kwentus, Mikhil Bamne, Annie M. Watson, Rodney T. Perry, Lambertus Klei, Trina B. Allen, Alberto B. Santos, Joseph P. McEvoy, Henry A. Nasrallah, B. Devlin, Cemil Çelik, L. DiAnne Bradford, Raquel E. Gur, Joel Wood, Hader Mansour, Robert Savage, Neil B. Edwards, Monica E. Calkins, Rodney C.P. Go, Robert H. Yolken, Vishwajit L. Nimgaonkar, Ruben C. Gur, Kodavali V. Chowdari
Publikováno v:
Schizophrenia Bulletin. 38:1149-1154
Background: Genome-wide association studies (GWAS) implicate single nucleotide polymorphisms (SNPs) on chromosome 6p21.3-22.1, the human leukocyte antigen (HLA) region, as common risk factors for schizophrenia (SZ). Other studies implicate viral and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f7a0931942e9de756f720dce8eebd
https://doi.org/10.1093/schbul/sbs087
https://doi.org/10.1093/schbul/sbs087
Autor:
Neil B. Edwards, L. D. Bradford, Bernie Devlin, Raquel E. Gur, Adrienne C. Lahti, Judith Rosemary O'Jile, Alberto B. Santos, Henry A. Nasrallah, Joseph P. McEvoy, Vishwajit L. Nimgaonkar, Monica E. Calkins, Roberta S. May, Trina B. Allen, Howard W. Wiener, Joseph Kwentus, T. Aduroja, Rodney C.P. Go, L. Montgomery-Barefield, Robert Savage
Publikováno v:
Schizophrenia Research. 139:105-109
The role of daily functioning is an integral part of the schizophrenia (SZ) phenotype and deficits in this trait appear to be present in both affected persons and some unaffected relatives; hence we have examined its heritability in our cohort of Afr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0b26dd84f4d848efb98f8d82fbd75b
https://doi.org/10.1016/j.schres.2012.04.015
https://doi.org/10.1016/j.schres.2012.04.015
Autor:
Raquel E. Gur, Vishwajit L. Nimgaonkar, Neil B. Edwards, Rodney C.P. Go, Alberto B. Santos, Robert Savage, Bernie Devlin, Trina B. Allen, Howard W. Wiener, Joseph P. McEvoy, Ruben C. Gur, Jan Richard, Joseph Kwentus, L. DiAnne Bradford, Lambertus Klei, Monica E. Calkins, Joel Wood
Publikováno v:
Schizophrenia Bulletin
Objective: Various measures of neurocognitive function show mean differences among individuals with schizophrenia (SZ), their relatives, and population controls. We use eigenvector transformations that maximize heritability of multiple neurocognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11e67dba913541daa8660f2d810be93
https://doi.org/10.1093/schbul/sbr161
https://doi.org/10.1093/schbul/sbr161
Autor:
Robert M. Hamer, Jason D. Kilts, Christine E. Marx, Jeffrey A. Lieberman, Trina B. Allen, Jennifer C. Naylor, Daniel W. Bradford, Jennifer L. Strauss
Publikováno v:
Neuroscience. 191:78-90
Emerging preclinical and clinical evidence suggests that pregnenolone may be a promising novel therapeutic candidate in schizophrenia. Pregnenolone is a neurosteroid with pleiotropic actions in rodents that include the enhancement of learning and mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe58dce8d85252e29329fefb6c96d54
https://doi.org/10.1016/j.neuroscience.2011.06.076
https://doi.org/10.1016/j.neuroscience.2011.06.076
Autor:
Jennifer L. Strauss, John F. Ervin, David C. Steffens, Jason D. Kilts, Christine E. Marx, Christine M. Hulette, Trina B. Allen, Nagy A. Youssef, Mark W. Massing, Victoria M. Payne, Lawrence J. Shampine, Dan G. Blazer, Jennifer C. Naylor
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1801:951-959
The neurosteroid allopregnanolone has pronounced neuroprotective actions, increases myelination, and enhances neurogenesis. Evidence suggests that allopregnanolone dysregulation may play a role in the pathophysiology of Alzheimer's disease (AD) and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ae02c4b486c0d2b57587b08c5204a6
https://doi.org/10.1016/j.bbalip.2010.05.006
https://doi.org/10.1016/j.bbalip.2010.05.006
Autor:
Joseph Kwentus, Raquel E. Gur, Trina B. Allen, L. DiAnne Bradford, Howard W. Wiener, J. Daniel Ragland, Judith Rosemary O'Jile, Bernie Devlin, Lambertus Klei, Alberto B. Santos, Ping Tepper, Vishwajit L. Nimgaonkar, Paul D. Lyons, Rodney C.P. Go, Monica E. Calkins, Neil B. Edwards, Robert Savage, Muktar H. Aliyu, Jan Richard, Ruben C. Gur
Publikováno v:
American Journal of Psychiatry. 167:459-472
Neurocognitive impairments in schizophrenia are well replicated and widely regarded as candidate endophenotypes that may facilitate understanding of schizophrenia genetics and pathophysiology. The Project Among African-Americans to Explore Risks for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::face767c7a689551443d31c084f44327
https://doi.org/10.1176/appi.ajp.2009.08091351
https://doi.org/10.1176/appi.ajp.2009.08091351
Autor:
Michael John Owen, L. Di Anne Bradford, Rodney C.P. Go, Neil B. Edwards, Lora McClain, Bernie Devlin, Raquel E. Gur, Ruben C. Gur, Robert Savage, Monica E. Calkins, Joseph P. McEvoy, Michael Conlon O'Donovan, Judith Rosemary O'Jile, Michael E. Talkowski, Draga Toncheva, Hader Mansour, Gerard Vockley, Lyudmila Georgieva, Trina B. Allen, Paul D. Lyons, Kodavali V. Chowdari, Alberto B. Santos, Joseph Kwentus, George Kirov, Joel Wood, Vishwajit L. Nimgaonkar
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :560-569
Recessive mutations in the phenylalanine hydroxylase (PAH) gene predispose to phenylketonuria (PKU) in conjunction with dietary exposure to phenylalanine. Previous studies have suggested PAH variations could confer risk for schizophrenia, but compreh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d973f48fefc670457901e22357ee05b
https://doi.org/10.1002/ajmg.b.30862
https://doi.org/10.1002/ajmg.b.30862
Autor:
Muktar H, Aliyu, Monica E, Calkins, Charlie L, Swanson, Paul D, Lyons, Robert M, Savage, Roberta, May, Howard, Wiener, Stephen, McLeod-Bryant, Bernie, Devlin, Vishwajit L, Nimgaonkar, J Daniel, Ragland, Raquel E, Gur, Ruben C, Gur, L Dianne, Bradford, Neil, Edwards, Joseph, Kwentus, Joseph P, McEvoy, Alberto B, Santos, Stephen, McCleod-Bryant, Clifton, Tennison, Rodney C P, Go, Trina B, Allen
Publikováno v:
Schizophrenia Research. 87:32-44
The Project among African-Americans to Explore Risks for Schizophrenia (PAARTNERS) is a multi-site, NIMH-funded study that seeks to identify genetic polymorphisms that confer susceptibility to schizophrenia among African-Americans by linkage mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1c75d1c581febaf924a0b99212df74
https://doi.org/10.1016/j.schres.2006.06.027
https://doi.org/10.1016/j.schres.2006.06.027
Autor:
Trina B. Allen, Joseph P. McEvoy
Publikováno v:
Current Drug Target -CNS & Neurological Disorders. 1:433-442
As the prevalence of tobacco use has decreased, it has become clear that individuals with mental illness comprise a substantial portion of the remaining smokers. Seventy to eighty percent of patients with schizophrenia smoke and their smoking is esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a33c414d5a648da2feaf7302143e1d
https://doi.org/10.2174/1568007023339210
https://doi.org/10.2174/1568007023339210