Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Trimazosin"'
Autor:
Catherine D. E. Wilder, Ellice Caldwell-Dunn, Michael J. Curtis, Antonella Ranieri, Tutku Dursun, Hannah R. Lewis, Paul Gyimah, Nikoleta Pavlaki
Publikováno v:
British Journal of Pharmacology. 175:1669-1690
BACKGROUND & PURPOSE: Antiarrhythmic β-blockers are used in patients at risk of myocardial ischaemia, but the survival benefit and mechanisms are unclear. We hypothesised that β-blockers do not prevent ventricular fibrillation (VF), but instead inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d583c478ffe7ee4872f65e8b276af605
https://doi.org/10.1111/bph.14176
https://doi.org/10.1111/bph.14176
Autor:
Aapo Lehtonen
Publikováno v:
Acta Medica Scandinavica. 218:213-216
The effects on plasma lipids, blood glucose and serum insulin levels of oral administration of trimazosin and pindolol over a 6-month period were studied in 11 patients with essential hypertension. Total plasma cholesterol and LDL cholesterol concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c9a1d93085de78cd3665501a3fb75a
https://doi.org/10.1111/j.0954-6820.1985.tb08849.x
https://doi.org/10.1111/j.0954-6820.1985.tb08849.x
Publikováno v:
British Journal of Pharmacology. 135:807-815
Ventricular fibrillation (VF) in conscious rats with coronary artery ligation occurs in two phases, before (phase 1) and after (phase 2) 90 min of ischaemia respectively. The mechanisms of phase 2 VF are not established. Interestingly, phase 2 VF is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f8dfad66b18ddb83d3ec6891c3d9e01
https://doi.org/10.1038/sj.bjp.0704509
https://doi.org/10.1038/sj.bjp.0704509
Autor:
P. Lund-Johansen, P. Omvik
Publikováno v:
European journal of clinical pharmacology. 40(2)
The long-term haemodynamic effect of sustained-release trimazosin (mean daily dose 418 mg) at rest and during exercise has been examined in 14 male patients (age 30-61 y) with previously untreated mild or moderate essential hypertension. Cardiac outp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5feec7d67e8b271081bff17f2b54280
https://pubmed.ncbi.nlm.nih.gov/2065694
https://pubmed.ncbi.nlm.nih.gov/2065694
Autor:
S.Martin Shreeve
Publikováno v:
European journal of pharmacology. 188(1)
[3H]Prazosin bound to a single class of high-affinity sites in both bovine aortic and rat hepatic membranes. The absolute affinity values of displacing ligands (prazosin greater than doxazosin much greater than trimazosin greater than yohimbine) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133b095b80b6c046759536b507405606
https://pubmed.ncbi.nlm.nih.gov/2155124
https://pubmed.ncbi.nlm.nih.gov/2155124
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Publikováno v:
American Heart Journal. 108:124-131
The efficacy of acute beta blockade in essential hypertension is limited by reflex vasoconstriction. The aim of this study was to determine whether the latter response was modified by prior selective alpha-1-adrenoceptor blockade. A single-blind, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d3b573aefa93b0479359f6fc509a8c
https://doi.org/10.1016/0002-8703(84)90554-4
https://doi.org/10.1016/0002-8703(84)90554-4
Autor:
Joseph A. Franciosa, Jay N. Cohn
Publikováno v:
Clinical Pharmacology & Therapeutics. 23:11-18
Trimazosin is a new quinazoline derivative vasodilator previously thought to act primarily on resistance vessels. Vasodilators characteristically improve hemodynamics in patients with left ventricular failure. Trimazosin in single oral doses of 100 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be3512ecc81cd782a0a11f7298eeaa
https://doi.org/10.1002/cpt197823111
https://doi.org/10.1002/cpt197823111
Publikováno v:
American Heart Journal. 106:1228-1234
Pharmacokinetics and bioavailability of a trimazosin sustained-release tablet (SRT) formulation (300 mg) were studied in healthy volunteers. In the first study of 12 subjects, the bioequivalence of trimazosin, 100 mg, in a standard tablet (ST) and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dc4c31473f65ba0aeacc4b9e5c09a0
https://doi.org/10.1016/0002-8703(83)90180-1
https://doi.org/10.1016/0002-8703(83)90180-1
Publikováno v:
Journal of Cardiovascular Pharmacology. 7:913-918
The relationships between the effects on blood pressure and vascular responsiveness, and the whole blood concentration of the antihypertensive drug trimazosin and its major metabolite were investigated in six normotensive male volunteers following 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d324c39ca34c25946d7347d87f146a
https://doi.org/10.1097/00005344-198509000-00015
https://doi.org/10.1097/00005344-198509000-00015