Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis.

Autor: Faust HJ; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Cheng TY; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Korsunsky I; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Watts GFM; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Gal-Oz ST; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Trim WV; Department of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Kongthong S; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Jonsson AH; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Simmons DP; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Zhang F; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Rheumatology and the Center for Health Artificial Intelligence, University of Colorado School of Medicine, Aurora, CO, USA., Padera R; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Chubinskaya S; Department of Pediatrics, Rush Medical College, Chicago, IL, USA., Wei K; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Raychaudhuri S; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Lynch L; Department of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Moody DB; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Brenner MB; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. mbrenner@bwh.harvard.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 14; Vol. 15 (1), pp. 9859. Date of Electronic Publication: 2024 Nov 14.

The impact of physical inactivity on glucose homeostasis when diet is adjusted to maintain energy balance in healthy, young males.

Autor: Trim WV; University of Bath, Centre for Nutrition, Exercise and Metabolism (CNEM), Department for Health, United Kingdom., Walhin JP; University of Bath, Centre for Nutrition, Exercise and Metabolism (CNEM), Department for Health, United Kingdom., Koumanov F; University of Bath, Centre for Nutrition, Exercise and Metabolism (CNEM), Department for Health, United Kingdom., Turner JE; University of Bath, Centre for Nutrition, Exercise and Metabolism (CNEM), Department for Health, United Kingdom., Shur NF; Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom; National Institute for Health and Care Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom., Simpson EJ; National Institute for Health and Care Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom; MRC/Versus Arthritis Centre for Musculoskeletal Ageing Research, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, United Kingdom., Macdonald IA; National Institute for Health and Care Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom; MRC/Versus Arthritis Centre for Musculoskeletal Ageing Research, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, United Kingdom., Greenhaff PL; Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom; National Institute for Health and Care Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom; MRC/Versus Arthritis Centre for Musculoskeletal Ageing Research, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, United Kingdom., Thompson D; University of Bath, Centre for Nutrition, Exercise and Metabolism (CNEM), Department for Health, United Kingdom. Electronic address: D.Thompson@bath.ac.uk.

Publikováno v: Clinical nutrition (Edinburgh, Scotland) [Clin Nutr] 2023 Apr; Vol. 42 (4), pp. 532-540. Date of Electronic Publication: 2023 Feb 16.

Divergent immunometabolic changes in adipose tissue and skeletal muscle with ageing in healthy humans.

Autor: Trim WV; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Walhin JP; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Koumanov F; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Bouloumié A; INSERM UMR1048, Université Paul Sabatier, I2MC, Toulouse, France., Lindsay MA; Department of Pharmacy and Pharmacology, University of Bath, Bath, Somerset, UK., Chen YC; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Travers RL; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Turner JE; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK., Thompson D; Department for Health, Centre for Nutrition, Exercise, and Metabolism, University of Bath, Bath, Somerset, UK.

Publikováno v: The Journal of physiology [J Physiol] 2022 Feb; Vol. 600 (4), pp. 921-947. Date of Electronic Publication: 2021 Jun 01.

The effect of hydration status on plasma FGF21 concentrations in humans: A subanalysis of a randomised crossover trial.

Autor: Carroll HA; Department for Health, University of Bath, Bath, United Kingdom.; Cardiovascular Research-Hypertension, Clinical Research Centre, Lund University, Malmö, Sweden., Chen YC; Department of Physical Education, National Taiwan Normal University, Taipei, Taiwan.; Institute for Research Excellence in Learning Science, National Taiwan Normal University, Taipei, Taiwan., Templeman I; Department for Health, University of Bath, Bath, United Kingdom., James LJ; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom., Betts JA; Department for Health, University of Bath, Bath, United Kingdom., Trim WV; Department for Health, University of Bath, Bath, United Kingdom.

Publikováno v: PloS one [PLoS One] 2020 Aug 05; Vol. 15 (8), pp. e0235557. Date of Electronic Publication: 2020 Aug 05 (Print Publication: 2020).