Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Trilby E. Williams"'
Autor:
R D Robinson, Trilby E. Williams, Richard A. Ferraina, W. Steven Head, George Foulds, Denis M. O'Day
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 10:633-641
Azithromycin was orally administered to Dutch-belted rabbits following extracapsular lens extraction in one eye. At various times the animals were sacrificed, and serum and ocular tissues were obtained for drug level determination by HPLC-EC. Followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b8caef9e545b4ad26e9ed140ad7fca
https://doi.org/10.1089/jop.1994.10.633
https://doi.org/10.1089/jop.1994.10.633
Publikováno v:
Cornea. 10:411-417
The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f014d2480bb917a0955158e4b23351
https://doi.org/10.1097/00003226-199109000-00010
https://doi.org/10.1097/00003226-199109000-00010
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 228:538-540
Measuring precise antifungal levels in the cornea with broth-dilution bioassays is difficult, as standard techniques involving visual determination of endpoints are hindered by corneal debris. To increase the precision of the measurement, we modified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcb47f4cdc56d1b8951ad4532721d88
https://doi.org/10.1007/bf00918487
https://doi.org/10.1007/bf00918487
Publikováno v:
Cornea. 12(6)
Dutch-belted rabbits with corneal epithelium either intact or debrided were injected subconjunctivally with 300 microliters of one of six antifungal agents: 10 mg/ml miconazole, 5 mg/ml fluconazole, 5 mg/ml ketoconazole, 2.5 mg/ml itraconazole, and 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a737d0c406be2e48fc05afe6ecda552a
https://pubmed.ncbi.nlm.nih.gov/8261783
https://pubmed.ncbi.nlm.nih.gov/8261783
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 110(4)
The ocular pharmacokinetics of saperconazole, an experimental lipophilic triazole with activity against filamentous fungi, including Aspergillus and Candida species, were evaluated in rabbits by radioassay. The drug was administered by topical, subco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc39419e7702f676326ec7ade0d6f97e
https://pubmed.ncbi.nlm.nih.gov/1562266
https://pubmed.ncbi.nlm.nih.gov/1562266
Publikováno v:
Current eye research. 11(1)
Two different measures of response to therapy were evaluated in a model of keratitis caused by Aspergillus fumigatus in Dutch-belted rabbits. Combined pre and post-inoculation treatment with oral fluconazole 37.5 mg/kg bid or itraconazole 40 mg/kg bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff69aadb707068c3128ccac7c0e30f9
https://pubmed.ncbi.nlm.nih.gov/1313750
https://pubmed.ncbi.nlm.nih.gov/1313750
Publikováno v:
American journal of ophthalmology. 112(5)
After intrastromal injection of a standardized inoculum of Candida albicans blastoconidia in Dutch-belted rabbits, the efficacy of subconjunctival therapy with amphotericin B and miconazole was evaluated using a quantitative isolate recovery techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8500a34a74e97bd6387c5a5c20e56477
https://pubmed.ncbi.nlm.nih.gov/1951595
https://pubmed.ncbi.nlm.nih.gov/1951595
Publikováno v:
Journal of ocular pharmacology. 7(4)
The effect of the intrastromal injection of a mixture of amphotericin B, miconazole, natamycin, and nystatin and the component agents alone was studied in Dutch-belted rabbits by standard bioassay. Twenty-four hours following injection, the inhibitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63209a7f5a8ef3b8a4ebdda4b4146614
https://pubmed.ncbi.nlm.nih.gov/1809791
https://pubmed.ncbi.nlm.nih.gov/1809791
Publikováno v:
Archives of Ophthalmology. 109:1601
To assess the effect of corticosteroid on the establishment of experimentally induced keratomycoses, rabbits were injected subconjunctivally with triamcinolone acetonide on two successive days before inoculation with Candida albicans, Aspergillus fum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b06cfd695d2ccb54382b11b09bbd7d3
https://doi.org/10.1001/archopht.1991.01080110139051
https://doi.org/10.1001/archopht.1991.01080110139051
Examination of the Contact Lens with Light Microscopy: An Aid in Diagnosis of Acanthamoeba Keratitis
Publikováno v:
Clinical Infectious Diseases. 13:S425-S425
The demonstration of amebic cysts on the surface of a patient's hydrophilic contact lens by direct examination with light microscopy can provide rapid confirmation of the diagnosis of acanthamoeba keratitis. This technique is a simple, quick, and non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40247678642056200ae9b65655971c25
https://doi.org/10.1093/clind/13.supplement_5.s425
https://doi.org/10.1093/clind/13.supplement_5.s425