Comparison of kidney transplant outcomes in HLA compatible and incompatible transplantation: a national cohort study

Autor: Trijntje J. W. Rennie, Richard K. Battle, Angela A. Abel, Sylvia McConnell, Robert McLaren, Paul J. Phelan, Colin Geddes, Neal Padmanabhan, Marc J. Clancy, Ann‐Margaret Little, David M. Turner

Background: \ud Reports of HLA incompatible (HLAi) kidney transplant outcomes are inconclusive, especially in the context of lower level Donor Specific Antibodies (DSA).\ud \ud Methods: \ud Multi-centre national cohort study of HLAi kidney transplant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d81fe3059d745e08cdf91f7522fd77
https://eprints.gla.ac.uk/278507/1/278507.pdf

Highly sensitised patients awaiting deceased donor renal transplants are disadvantaged by the presence of denatured HLA antibody detected in routine HLA antibody testing

Autor: Richard K. Battle, Trijntje J. W. Rennie, Paul J. Phelan, Angela A. Abel, Sylvia McConnell, David M. Turner

Publikováno v: HLAREFERENCES. 100(1)

Luminex single antigen bead (SAB) assays used to detect HLA antibodies may artificially increase sensitisation in highly sensitised patients (HSP). The presence of denatured HLA (dHLA) within the assay enables antibodies specific to cryptic HLA epito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f760e56434e14cbfeb8529c3db4b477e
https://pubmed.ncbi.nlm.nih.gov/35150076

The impact of age on patient tolerance of mycophenolate following kidney transplantation

Autor: Nicola Joss, Jamie P. Traynor, Lorna Henderson, Wendy Metcalfe, Paul J. Phelan, Lorna Marson, Trijntje J. W. Rennie, Ellen Barton, Marc Clancy, Colin Geddes, Michaela Petrie, David Walbaum

Publikováno v: Rennie, T, Petrie, M, Metcalfe, W, Walbaum, D, Joss, N, Barton, E, Marson, L P, Clancy, M J, Henderson, L, Traynor, J P, Geddes, C & Phelan, P J 2020, ' The impact of age on patient tolerance of mycophenolate following kidney transplantation ', Nephrology . https://doi.org/10.1111/nep.13718

Background: In Scotland, standard maintenance immunosuppression following kidney transplantation consists of mycophenolate (MPA), tacrolimus and prednisolone irrespective of recipient age. We analysed the tolerability of this immunosuppression regime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14176ffb28b5a037be563033d57feea1
https://pubmed.ncbi.nlm.nih.gov/32323461