Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection.

Autor: Zec K; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom., Thiebes S; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Bottek J; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Siemes D; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Spangenberg P; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Trieu DV; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Kirstein N; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Subramaniam N; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Christ R; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Klein D; Institute for Cell Biology (Cancer Research), University Hospital Essen, Essen, Germany., Jendrossek V; Institute for Cell Biology (Cancer Research), University Hospital Essen, Essen, Germany., Loose M; Clinic for Urology, Paediatric Urology and Andrology, Justus-Liebig University of Giessen, Giessen, Germany., Wagenlehner F; Clinic for Urology, Paediatric Urology and Andrology, Justus-Liebig University of Giessen, Giessen, Germany., Jablonska J; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Bracht T; Medical Faculty, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany.; Clinic for Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Knappschafts-krankenhaus Bochum, Bochum, Germany., Sitek B; Medical Faculty, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany.; Clinic for Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Knappschafts-krankenhaus Bochum, Bochum, Germany., Budeus B; Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen, Essen, Germany., Klein-Hitpass L; Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen, Essen, Germany., Theegarten D; Institute of Pathology, University Hospital Essen, Essen, Germany., Shevchuk O; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany., Engel DR; Institute for Experimental Immunology and Imaging, Department of Immunodynamics, University Hospital Essen, Essen, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Sep 18; Vol. 14, pp. 1227191. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023).